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EWG’s 2019 Guide to Sunscreens was researched and written by David Andrews, senior scientist; Carla Burns, research & database analyst; Sean Gray, director of consumer database architecture; Nneka Leiba, director of healthy living science; Kali Rauhe, associate database analyst; and Sydney Swanson, associate database analyst.
EWG’s 13th annual analysis of sunscreens includes hazard and efficacy ratings for more than 750 sunscreens, 450 SPF-labeled moisturizers and more than 120 lip products. The ratings are based on an in-house compilation of standard industry, government and academic data sources; models we constructed over the past 13 years; and a thorough review of the technical literature on sunscreens. The sunscreen ratings from this investigation have been incorporated into EWG’s Skin Deep® cosmetics database, an online consumer tool available at www.ewg.org/skindeep.
We based the analysis on sunscreen ingredient listings obtained primarily from our data partner, Label Insight; direct company submissions; and online and brick-and-mortar retailers.
Products are rated on five factors encompassing overall ingredient hazard and product efficacy in providing sun protection:
The overall rating for each product was calculated on the basis of a formula reflecting a combination of the product’s health hazard and efficacy ratings. Efficacy accounts for two-thirds of the score for products with lower health hazard concerns and for one-half the score in products with high health hazard scores.
We also gave additional weight in the calculated scores if products included a banned FDA sunscreen marketing claim on the label, such as sunblock.
The methods and content of the analysis were based on EWG’s review of the technical literature, including hundreds of industry and peer-reviewed studies. Results of the analysis appear in EWG’s online, interactive sunscreen guide. Details of the methodology are described below.
Health hazard scores were based on the ingredient health hazard scoring system of EWG’s Skin Deep database (www.ewg.org/skindeep). This core database of chemical hazards, regulatory status and study availability pools data from nearly 60 databases and from government agencies, industry panels, academic institutions or and credible bodies. The information in Skin Deep is used to create hazard ratings and data gap ratings for both personal care products and individual ingredients.
In addition, the hazard scores for mineral ingredients were adjusted to account for exposure potential calculated from evidence regarding skin penetration or absorption, as described in greater detail on the Skin Deep “About” page.
We gave additional weight in the calculated hazard scores to properties of particular concern for sunscreens, including products that contain oxybenzone or vitamin A, products in a spray or powder form that may pose a risk when inhaled, and products listing SPF values exceeding SPF 50+. For sunscreens with a single significant concern, we assigned a rating no lower than 3 (moderate hazard), and for sunscreens with two or more significant concerns, we assigned a rating no lower than 7 to reflect a higher level of concern.
Hazard scores in the sunscreen evaluations reflect hazards specific to sunscreens, as well as beneficial or potentially harmful effects of specific active ingredient combinations. We assessed hazards identified by government, industry and academic sources but did not evaluate specific claims made by individual manufacturers.
This report includes a closer look at the 16 chemicals permitted by the U.S. Food and Drug Administration for use as active ingredients in sunscreens – including the various particle sizes of the inorganic sunscreen ingredients zinc oxide and titanium dioxide. We compiled relevant information from sources that included the peer-reviewed literature and risk assessments from the European Union, Japan and Australia, and other countries with robust sunscreen regulations.
Sunscreens sold in the U.S. are considered over-the-counter drugs. They contain active ingredients that must undergo safety and effectiveness testing, and inactive ingredients that – as with virtually all other personal care products – do not require safety tests. We used different approaches to evaluate active and inactive ingredients.
Active ingredients, as well as specific active ingredient combinations, were evaluated based on an extensive review of the scientific literature. The review included peer-reviewed literature, filed and approved patents, and reviews by government and industry panels, as well as cross-checks with EWG’s Skin Deep database.
We conducted inactive ingredient assessments using the existing Skin Deep system we cited above (EWG 2019). Skin Deep identifies chemicals that pose health hazards, including known and probable carcinogens; reproductive and developmental toxicants; neurotoxic chemicals; skin irritants and allergens; chemicals flagged for persistence, bioaccumulation and toxicity in the environment; as well as chemicals banned or restricted in other countries. Skin Deep assessments also highlight the extensive data gaps that exist for the majority of ingredients used in cosmetics and personal care products.
Briefly, EWG’s hazard ratings are a synthesis of known and suspected hazards associated with ingredients and products. Skin Deep’s hazard ratings are categorized as raising low, moderate or higher concern, with numeric rankings that range from 0, or low concern, to 10, or high concern. Data gap ratings describe the extent to which ingredients or products have been definitively assessed for hazards.
Further details concerning this methodology may be found on the Skin Deep website (www.ewg.org/skindeep).
In the analysis of product effectiveness, we weighed four contributing factors:
We assigned a score for each factor based on an evaluation of the labeled SPF, EWG-modeled UV protection and the technical literature on sunscreen stability.
We derived an overall rating for product effectiveness as the sum of these four factors, weighted by their relative importance. In this calculation we assigned a weight of 0.28 each to UVA protection, UVB protection and UVA/UVB balanced protection, and a weight of 0.16 to stability. The procedures are described in greater detail below.
UVB protection is based on each product’s SPF, or sun protection factor, rating as labeled on the product.
We scored UVB protection from sunscreens with SPF values between 15 and 110 as effective for sunburn protection, with a score of zero. This is based on the assumption that consumers would pick a product with the appropriate SPF based on their skin tone, solar intensity and time outdoors. Sunscreens with SPF values lower than 15 are not evaluated in our database.
When EWG modeled SPF value for a given product that was less than half of the labeled value, we added three points to the product’s overall score because of concerns about the efficacy of the product and the likely use of inactive ingredients to boost the SPF value. EWG is concerned that SPF boosters are increasingly common in U.S. sunscreens. Many such boosters inhibit sunburn but do not appear to change the absorbance spectrum of sunscreen (Kobo 2015), meaning that they do not prevent UV rays from striking skin. There are serious, unanswered questions about whether these ingredients protect skin from other types of UV damage.
To score products on UVA protection (Section 2) and the balance of UVA to UVB protection (Section 3), we modeled the effectiveness of the sunscreen on the basis of the active ingredients. Modeling the efficacy of sunscreen products based on the active ingredients is standard industry practice (BASF 2013). Modeling requires the absorbance spectrum for the active ingredient and the percent of the active ingredient used in the product.
Absorbance spectra are determined through experiments in which researchers measure the amount and type of UV light filtered out by an ingredient or ingredient combination at every wavelength along the UVA and UVB spectrum. With absorbance spectra, researchers determine the theoretical effectiveness of sunscreen ingredients and sunscreen products in preventing UV radiation from reaching the skin.
Figure 1: Example of modeled absorption spectrum of avobenzone
|4-Methylbenzylidine Camphor (4-MBC)||(Vanquerp 1999)|
|Avobenzone (Parsol 1789 | Butyl Methoxydibenzoylmethane)||(Bonda 2005, BASF 2010)|
|Ensulizole (Phenylbenzimidazole Sulfonic Acid)||(Inbaraj 2002)|
|Homosalate||(Sánchez and Cuesta 2005)|
|Menthyl Anthranilate (Beeby and Jones 2000)||(Beeby 2000)|
|Mexoryl SX||(Herzog 2005b)|
|Sunscreen Grade Titanium Dioxide||(Schlossman 2005)1|
|Sunscreen Grade Zinc Oxide||(Schlossman 2005, EWG 2010, BASF 2009, Nanox 2009)1|
|Octinoxate (Octyl Methoxycinnamate)||(Bonda 2005)|
|Octisalate (Octyl Salicylate)||(Krishnan 2004)|
|Oxybenzone (Benzophenone-3)||(Vanquerp 1999)|
|Padimate O (Octyl Dimethyl PABA | PABA Ester)||(Krishnan 2004)|
|Sulisobenzone (Benzophenone-4) (CIR 2006)||(Sánchez 2005)|
|Tinosorb M (MBBT)||(Herzog 2005b)|
|Tinosorb S||(Herzog 2005b)|
Both SPF and monochromatic protection factor, or MPF, are unitless factors that provide a measure of the UV radiation blocked by sunscreen. SPF is a single value, whereas MPF varies according to wavelength. In the U.S., SPF is derived from sunburn experiments on human volunteers, and MPF is derived from lab measurements of UV transmission (Herzog 2005). SPF can also be computed by combining the MPF spectrum with the effective action spectrum for sunburn, a measure of how much damage a particular wavelength of light will cause (McKinlay 1987).
The MPF is a measure of the amount of UV radiation blocked (i.e., absorbed or scattered) at a particular wavelength and is a key component in EWG’s evaluation of sunscreen effectiveness. We developed UV transmission spectra for individual active ingredients and for all combinations of active ingredients in the products assessed. Our report uses the MPF transmission spectrum to graphically represent the effectiveness of sunscreen products and ingredients across the UV spectrum and to calculate the effectiveness of products in the UVA range. In the UVB range, we use SPF instead of MPF as the measure of product effectiveness.
We computed the MPF transmission spectra following the method detailed by Herzog and implemented by the BASF sunscreen simulator, formerly known as the Ciba sunscreen simulator (Herzog 2002, Herzog 2006, BASF 2011). This model accounts for the effect of uneven skin surfaces – skin is not a smooth surface, but a series of ridges and valleys. The model represents sunscreen on the skin as an unevenly distributed thin film. The sunscreen thickness is modeled using a continuous height distribution that matches a gamma distribution function (Ferrero 2003). The gamma method provides a significant improvement in the calculated correlation with measured SPF over the previously used two-step model (O’Neill 1984).
MPF is given by:
where T is the percent transmission of light; ε(λ) is the average molecular absorption coefficient (as defined by Herzog); c is the average molar concentration of the active ingredients in moles/liter; d is the path length (20 micrometers is the assumed thickness of sunscreen based upon the recommended applied dose of 2 mg/cm2); and g and f are parameters fitted by Herzog (Herzog 2002, Herzog 2006) to match experimental data on European sunscreens equaling 0.269 and 0.935, respectively. Once the transmission spectrum is obtained, it can be transformed into an absorbance spectrum and MPF.
We used the Herzog method (Herzog 2002, Herzog 2006) described above to compute the UV transmission spectra both for individual ingredients and for all variations of active ingredients in the products assessed. The method requires entering the concentrations of active ingredients. In computations of MPF spectra for individual ingredients, we used the average concentration of that ingredient found in the products assessed. In computations of MPF spectra, we used the concentrations of active ingredients specified on the product label. For some products, the concentrations of active ingredients were not available. In those cases, we used the following hierarchy to establish assumed concentrations of active ingredients used in the MPF analysis:
We evaluated sunscreen effectiveness in part on the basis of our computation of the transmission spectrum for a product’s combination of active ingredients. We integrated the combined effective absorbance spectrum as described by Herzog (Herzog 2002, Herzog 2006) over 1 nm wavelength intervals to obtain overall sunscreen product spectra based on the individual ingredient spectra described above. The spectral information is presented in this report over 10 nm wavelength intervals.
A sunscreen must generally contain multiple active ingredients to achieve a high SPF rating due to FDA-imposed concentration limits and constraints on product formulation (Chatelain 2001).
In evaluating overall UVA effectiveness, we calculated the percentage of UVA light blocked or absorbed from our modeled spectrum of the product. This calculation provides a numeric measure of the degree of UVA protection. This value was calculated by integrating the MPF between 320 to 400 nm.
Using this method, a score was assigned to each product:
Table 1: UVA score and percent of UVA light blocked
|Percent UVA blocked or absorbed||UVA protection score|
Government agencies, sunscreen researchers and the American Association of Dermatology recognize the need for sunscreens to offer proportionate protection from UVA and UVB radiation.
In 2009 we shifted from the spectral uniformity index for measuring sunscreen balance to a method based on the ratio of our modeled UVA protection factor, or UVAPF, to the labeled SPF. This method better accounts for imbalance, particularly in the high-SPF range, and relies directly on manufacturers’ measured SPF values rather than modeled values.
We calculated a balance factor for each sunscreen as the ratio of the UVA-PF for persistent pigment darkening to the SPF value listed on product labels.
Using this method, a UVA/UVB balance score was assigned to each product:
Table 2: UVA/UVB balance score
|Ratio of UVA-PF/SPF||UVA/UVB Balance Score|
The European standard for UVA protection in sunscreens set by Cosmetics Europe requires them to have both a critical wavelength of 370 nm and a ratio of UVAPF to SPF greater than one to three. The UVA protection factor is calculated by weighting the absorbance spectrum between 320 and 400 nm with the persistent pigment-darkening action spectra (Cosmetics Europe 2011).
Beginning in 2012, sunscreens sold and labeled as providing broad-spectrum protection have been required to have a critical wavelength of 370 nm (FDA 2011). The FDA standards do little to differentiate mediocre from excellent products. The standards have been criticized for providing no incentive for improvement (Diffey 2012).
Absorption of UV light causes many sunscreen active ingredients to go through chemical reactions or structural changes on the skin. In most cases, these ingredients quickly return to their original form to absorb more energy. However, ingredients can also degrade and in some cases even lose their UV protectiveness. One study found that seven of 14 common sunscreens in Europe photodegraded significantly after exposure to UV radiation, specifically UVA radiation (Shaath 1990).
In certain cases, degradation may produce other chemicals that are toxic to skin and body cells, especially if the sunscreen has been absorbed into the skin (Gasparro 1997), or the reactions can speed up – or catalyze – degradation of other ingredients in the sunscreen mixture (Bonda 2005).
EWG would like to have laboratory results of photodegradation for every active ingredient in every sunscreen product. However, since this information is not publicly available and such tests are not required of manufacturers, we analyzed a large number of studies from various sources. In quantifying these studies, it is difficult to compare results because of differences in the experimental conditions, such as solvent versus sunscreen formulation, measurement of light energy and sample preparation. Additionally, the degradation rate of an ingredient in a dilute laboratory solvent such as water or ethanol may or may not be representative of a consumer’s use. Even results in one sunscreen formulation may not be representative of the results in another because of variations in how active ingredients behave in different environments.
EWG performed linear regression analyses of percent degradation versus minimal erythemal dose, or MED – the minimal amount of UV radiation that will produce skin redness or sunburn, exposures in solvent and sunscreen formulations. The regression equations for solvent and sunscreen systems were then weighted equally and classified into three categories:
Table 3: Scoring ingredient stability
|Stability classification||Extent of Photo-degradation after 2 hours of peak intensity sun exposure (10 MEDs)|
|Major photodegradation||Over 25% breakdown|
|Minor photodegradation||5% to 25% breakdown|
|No photodegradation (Photo-stable)||Less than 5% breakdown|
We weighted solvent and formulation results equally because of the wide variation in test conditions and the possibility that a single sunscreen formulation may not be representative of other formulations.
There is insufficient information in the literature on the subject of photostability to reliably guide a sunscreen formulator reliably, let alone the consumer. Our classifications are presented here:
Table 4: Degradation of active ingredients
|Active ingredient||Classification percent||Degradation with exposure to 10 MEDs|
|4-Methylbenzylidine Camphor (4-MBC) (Deflandre 1988; Vanquerp 1999)||None||Less than 1|
|Avobenzone (Parsol 1789 | Butyl Methoxydibenzoylmethane) (Deflandre 1988; Shaath 1990; Roscher 1994; Schwack 1995)||Major||42.1|
|Ensulizole (Phenylbenzimidazole Sulfonic Acid) (Deflandre 1988, Serpone 2002) — Deflandre found insignificant degradation in a sunscreen formulation, Serpone measured fast degradation in various solvents.||Major||46.6|
|Homosalate (Berset 1996, Herzog 2002)||Minor||6.7 – 60|
|Menthyl Anthranilate (Beeby 2000)||None||No degradation|
|Mexoryl SX (TDSA) (Deflandre 1988, Cantrell 1999, Herzog 2005)||Minor||21.2|
|Micronized Titanium Dioxide (Schlossman and Shao 2005)||None||No degradation|
|Micronized Zinc Oxide (Schlossman and Shao 2005)||None||No degradation|
|Octinoxate (Octyl Methoxycinnamate) (Deflandre 1988, Shaath 1990, Berset 1996, Chatelain 2001, Serpone 2002)||Minor||24.8|
|Octisalate (Octyl Salicylate) (Shaath 1990, Bonda 2005)||None||3.3|
|Octocrylene (Shaath 1990, Bonda 2005)||None||1.6|
|Oxybenzone (Benzophenone-3) (Deflandre 1988, Shaath 1990, Roscher 1994, Berset 1996, Chatelain 2001, Serpone 2002)||Minor||21.9|
|Padimate O (Octyl Dimethyl PABA | PABA Ester) (Deflandre 1988, Serpone 2002)||Major||44.7|
|Sulisobenzone (Benzophenone-4) (CIR 2006)||None||No degradation expected|
|Tinosorb M (MBBT) (Herzo, 2002, Herzog 2005)||None||1|
|Tinosorb S (BEMT) (Chatelain 2001, Bonda 2005, Damiani 2007)||None||1|
In order to account for a situation where an individual ingredient may photodegrade but the sunscreen itself continues to provide significant protection due to the presence of other active ingredients, we assumed that the UV-blocking effectiveness of an active ingredient experiencing major degradation is reduced by 50 percent, and the UV-blocking effectiveness of an active ingredient with minor degradation is reduced by 25 percent.
We then reintegrated over the entire spectrum and compared the degraded spectrum to the original. UVA and UVB protection were weighted equally. Based on the relative amount of degradation, the following scores were applied separately to the UVA and UVB portions:
Table 5: Stability scoring
|% blocking remaining after 10 MED (approximately 2 hours of sun exposure)||Score|
|% Area >90%||0|
|80 < % Area< 90%||1|
|70% < % Area< 80%||2|
|60% < % Area< 70%||3|
|% Area <60%||4|
Menthyl Anthranilate and Padimate O fluoresce when exposed to sunlight, meaning they absorb energy in the UVB range and re-emit it in the UVA range. If an active ingredient fluoresces, we increased the stability score by one point.
The scores for UVA, UVB and fluorescence were added together to determine the overall stability score, which ranged from 0 to 9, and were then scaled to a range of 0 to 10.
Several inactive ingredients help prevent sun damage through mechanisms other than blocking UV rays. For example, a variety of antioxidants scavenge free radicals in cells (Klein 2005). In some cases, claims made for these ingredients are unregulated (Klein 2005), whereas in others, the SPF itself can no longer be predicted by the sun-blocking ability of the active ingredients alone (Stanfield 2005). In the latter case, consumers are misled into believing they are receiving more protection than they actually are. For these ingredients, we attenuate the UVA and UVB scores as follows:
Table 6: Antioxidant scoring adjustments
|Raw score||Score category||Description|
|Attenuating score (improves UVB score by 10%)||Additional protection against UVB-induced damage||Anti-oxidants protect against UVB induced radiation damage|
|Attenuating score (improves UVA score by 10%)||Additional protection against UVA induced damage||anti-oxidants protect against UVA induced radiation damage|
The absorbance spectra for titanium dioxide and zinc oxide vary according to the size of the particle. Companies are not required to provide particle size information on package labels, leaving EWG with little information to use in determining the size and properties of the specific mineral ingredients used (FOE 2009, FDA 2007). EWG based the absorbance spectra on an average of the most likely particle sizes found in products containing titanium dioxide and zinc oxide. The information was based on our review of particle size and surface coatings for zinc oxide and titanium dioxide found on the company websites of sunscreen manufacturers and formulators.
When the shortest dimension of the primary particles of titanium dioxide is 15 nm, it appears transparent on skin, but at 35 to 60 nm it becomes opaque (Schlossman 2005). All information we have amassed from about 10 different titanium dioxide suppliers indicated primary particle sizes of 10 to 35 nm. Without clear regulatory guidelines, manufacturers and product formulators can claim they are using or not using nanoparticles without providing information to back up those claims. We assume that all UV attenuation-grade titanium dioxide sunscreens that appear clear on the skin use titanium dioxide with a mean primary particle size of 15 to 35 nm in the shortest dimension.
Table 7: Characteristics of sunscreen-grade titanium dioxide
|Titanium Dioxide Suppliers and Products|
|Supplier||Product||Crystal form||Primary particle size||Surface coating||Source|
|BASF||T-Lite SF-S||Rutile||30 nm*60 nm*10 nm, may aggregate into larger particles||Methicone||Gamer 2006|
|BASF||T-LITE SF||Rutile||30 nm*60 nm*10 nm, may aggregate into larger particles||Silica, Methicone||Gamer 2006|
|BASF||Uvinul TiO2||75% anatase/25% rutile||21 nm, agglomerate to 100 nm||trimethoxyoctysilyl||BASF 2006|
|Degussa||P-25||Anatase||21 nm||None, trimethyloctylsilane||Mavon 2007|
|EMD, Rona/Merck||Eusolex T-2000||Anatase||10 to 20 * 100 nm (possibly due to agglomeration)||Alumina, Dimethicone||NanoDerm 2007, SCCNFP 2000|
|EMD, Rona/Merck||Eusolex T-45D||Anatase||10-15 nm||Alumina/simethicone, oil dispersion||Sayre 2000|
|EMD, Rona/Merck||Eusolex T-AQUA||Anatase||10-15 nm||Alumina, water dispersion||Sayre 2000|
|ISK||TTO S-4||Rutile||15 nm||AHSA||Schlossman 2005|
|ISK||TTO S-3||Rutile||15 nm||Alumina||Schlossman 2005|
|ISK||TTO V-3||Rutile||10 nm||Alumina||Schlossman 2005|
|Kemira||UV Titan M170||Rutile||14 nm||Alumina, Methicone||Schlossman 2005|
|Kemira||UV Titan M262||Rutile||20 nm||Alumina, Dimethicone||SCCNFP 2000|
|Kobo Products||TEL-100||At least one dimension >100 nm, particles >100 when dispersed in ester||Aluminum hydroxide and silica||Kobo 2009|
|Kobo Products||MPT-154-NJE8||At least one dimension >100 nm||Alumina and jojoba esters||Kobo 2009|
|Kobo Products||TTO-NJE8||At least one dimension >100 nm||Alumina and jojoba esters||Kobo 2009|
|Sachtleben||Hombitec L5||Anatase||est. 15 nm (80-160 m2/g)||Silica, Silicone||Schlossman 2005|
|Showa Denka||Maxlight TS-04||35 nm||Silica||Schlossman 2005|
|Tayca||MT-100T||Rutile||15 nm||AS/AH||SCCNFP 2000|
|Tayca||MT-500B||Rutile||35 nm||Alumina||Schlossman 2005|
|Tayca||MT-100Z||Rutile||15 nm||AS/AH||Schlossman 2005|
|Titan Kogyo||Stt 65C-S||Anatase||est. 20 nm (64 m2/g)||None||Schlossman 2005|
Scientists estimate zinc oxide provides maximum UVB protection with particles size 20 to 30 nm, and the typical sizes of zinc particles in sunscreen are 30 to 200 nm (BASF 2011, Cross 2007, Nohynek 2007, Stamatakis 1990). Compared to larger particles, smaller particles provide greater UVB protection but less UVA protection (Schlossman 2005). Particles larger than about 200 to 300 nm tint the skin white and are unacceptable to most consumers (BASF 2000).
By default, EWG has assumed that zinc oxide used as an active ingredient in sunscreens has a 140 nm mean primary particle size. This applies when manufacturers indicate they use Z-Cote, a form of microfine zinc oxide, or non-nano minerals.
Table 8: Characteristics of sunscreen-grade zinc oxide
|Zinc Oxide Suppliers and Products|
|Supplier||Product||Primary particle size||Surface coating||Source|
|Antria/Dow||Zinclear-IM 50AB||2740nm||C12-15 Alkyl Benzoate (and) Isostearic Acid (and) Polyhydroxystearic Acid||Antaria 2010, Dow 2011|
|Antria/Dow||Zinclear-IM 50CCT||2740nm||Caprylic/Capric Triglyceride (and) Glyceryl Isostearate (and) Polyhydroxystearic Acid||Antaria 2010, Dow 2011|
|Antria/Dow||Zinclear-IM 50JJ||2740nm||Simmondsia Chinensis (Jojoba) Seed Oil (and) Glyceryl Isostearate (and) Polyhydroxystearic||Acid Antaria 2010, Dow 2011|
|Antria/Dow||Zinclear-IM 55L7||2740nm||Neopentyl Glycol Diheptanoate (and) Glyceryl Isostearate (and) Polyhydroxystearic Acid (and) Cetyl PEG-PPG-10/1 Dimethicone||Antaria 2010, Dow 2011|
|BASF||Z-Cote||80 nm (30 to 200 nm)||uncoated or dimethicone||BASF 2010|
|Elementis||Nanox 200||60 nm (17 m2/g)||None||Schlossman 2005|
|Kobo Products||ZnO-C-12||At least one dimension >100 nm||Isopropyl Titanium Triisostearate||Kobo 2009|
|Kobo Products||ZnO-C-11S4||At least one dimension >100 nm||Triethoxycaprylysilane||Kobo 2009|
|Kobo Products||ZnO-C-NJE3||At least one dimension >100 nm||Jojoba esters||Kobo 2009|
|Kobo Products||ZnO-C-DMC2||At least one dimension >100 nm||Diemethicone/Methicone Copolymer||Kobo 2009|
|Sakai||Finex, SF-20||60 nm (20 m2/g)||None||Schlossman 2005|
|Showa Denka||ZS-032||31 nm||Silica||Schlossman 2005|
|Sumitomo Cement||ZnO-350||35 nm||None||Schlossman 2005|
|Tayca||MZ-700||10-20 nm||None||Schlossman 2005|
|Tayca||MZ-500||20-30 nm||None||Schlossman 2005|
|Tayca||MZ-300||30-40 nm||None||Schlossman 2005|
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