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HC RED 3

Score:

Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (high) and Contamination concerns (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is HIGH

Products with this Ingredient

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Contamination concerns

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Chemical
NITROSAMINES

Allergies/immunotoxicity

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Concern Reference
HC Red 3 is an extreme contact sensitizer.Scientific Committee on Consumer Safety (SCCS), OPINION ON HC Red n° 3, COLIPA n° B50 September 2012. http://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_107.pdf
Human skin toxicant or allergen - strong evidenceFinal Report 3/04 Available from CIR
Human skin toxicant or allergen - strong evidenceEWG Assessment of Open Scientific Literature

Use restrictions

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Concern Reference
Banned in Canadian cosmetics used around the eyes.Health Canada 2011. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2011.
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panelCosmetic Ingredient Review Assessments
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review Assessments
Determined safe for use in cosmetics, subject to concentration or use limitations - anyCTFA International Cosmetic Ingredient Dictionary and Handbook

Cancer

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Concern Reference
Cancer - limited evidenceEWG Assessment of Open Scientific Literature
Cancer - limited evidenceCTFA International Cosmetic Ingredient Dictionary and Handbook
Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gapsWorld Health Organization, International Agency for Research on Cancer IARC Monographs Programme on the Evaluation of Carcinogenic Risks to Humans. Lists of Group 1, 2a, and 2b substances can be obtained. http://monographs.iarc.fr/ENG/Classification/index.php; Vol 57;1993

Data gaps

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Concern Reference
Insufficient data to determine safetyFinal Report 3/04 Available from CIR
4 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • Scientific Committee on Consumer Safety (SCCS), OPINION ON HC Red n° 3, COLIPA n° B50 September 2012. http://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_107.pdf
  • Final Report 3/04 Available from CIR
  • EWG Assessment of Open Scientific Literature
  • Health Canada 2011. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2011.
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
  • World Health Organization, International Agency for Research on Cancer IARC Monographs Programme on the Evaluation of Carcinogenic Risks to Humans. Lists of Group 1, 2a, and 2b substances can be obtained. http://monographs.iarc.fr/ENG/Classification/index.php; Vol 57;1993
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.

About this Ingredient's Score Range

  • Products with the EWG VERIFIED mark have met the program’s impurity restrictions based on EWG review of company data.

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