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SOYTRIMONIUM CHLORIDE

Score:

Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (low) and Irritation (skin, eyes, or lungs) (moderate)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is HIGH

Products with this Ingredient

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hair color and bleaching11 products

Allergies/immunotoxicity

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Concern Reference
A similar compound is a known human toxicant or allergenAOEC (Association of Occupational and Environmental Clinics) 2012. Asthmagen compilation - AEOC exposures codes.
Asthmagen sensitizer [Asthmagen, sensitizer induced according to Review by the Association of Occupational and Environmental Clinics (AOEC)] AOEC (Association of Occupational and Environmental Clinics) 2012. Asthmagen compilation - AEOC exposures codes.

Irritation (skin, eyes, or lungs)

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Concern Reference
Limited evidence of skin irritationOpen scientific literature

Developmental/reproductive toxicity

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Concern Reference
A peer-reviewed publication reports quaternary ammonium compounds cause reproductive toxicity in animals.Vanessa E Melin, Haritha Potineni, Patricia Hunt, Jodi Griswold, Bill Siems, Stephen R. Werre & Terry C. Hrubec. 2014. Exposure to common quaternary ammonium disinfectants decreases fertility in mice. Reproductive toxicology (Elmsford, N.Y.) 50, 163-70

Use restrictions

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Concern Reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsIJT 16(S3):195-220,1997 Tentative Amended Report 06/10

Ecotoxicology

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Concern Reference
Suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
EU currently assessing safety of use in hair dyes.Scientific Committee on Consumer Safety (SCCS) 2012. Opinion on Soytrimonium chloride, SCCS/1464/12. March 2012.
0 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • AOEC (Association of Occupational and Environmental Clinics) 2012. Asthmagen compilation - AEOC exposures codes.
  • Open scientific/peer reviewed literature
  • Vanessa E Melin, Haritha Potineni, Patricia Hunt, Jodi Griswold, Bill Siems, Stephen R. Werre & Terry C. Hrubec. 2014. Exposure to common quaternary ammonium disinfectants decreases fertility in mice. Reproductive toxicology (Elmsford, N.Y.) 50, 163-70
  • IJT 16(S3):195-220,1997 Tentative Amended Report 06/10
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • Scientific Committee on Consumer Safety (SCCS) 2012. Opinion on Soytrimonium chloride, SCCS/1464/12. March 2012.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About this Ingredient's Score Range

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