Find products and ingredients Learn how Skin Deep® works Meet our experts Discover EWG VERIFIED™

Data: Limited

Poloxamer 338

IMAGE SOURCE: PubChem

SEARCH PRODUCTS

Other Concerns

Persistence and bioaccumulation (moderate) and Non-reproductive organ system toxicity (moderate)

SYNONYMS

POLOXAMER 338

Poloxamer 338 is a polyoxyethylene, polyoxypropylene block polymer.

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • LOW
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

Expand content Collapse content
foundation90 products
mouthwash7 products
moisturizer7 products
blush7 products
hair color and bleaching6 products
serums & essences5 products
around-eye cream4 products
anti-aging3 products
toothpaste2 products
facial moisturizer/treatment2 products
facial powder1 products
setting powder/spray1 products
makeup primer1 products
tooth whitening1 products

Persistence and bioaccumulation

Expand content Collapse content
CONCERN REFERENCE
Persistent or bioaccumulative and moderate to high toxicity concern in humansEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

Expand content Collapse content
CONCERN REFERENCE
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Classified as medium human health priorityEnvironment Canada Domestic Substance List

Ecotoxicology

Expand content Collapse content
CONCERN REFERENCE
Suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data gaps

Expand content Collapse content
CONCERN REFERENCE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
Missing safety data noted by cosmetic industry reviewCosmetic Ingredient Review Assessments
Safety assessment was based on related chemicalCosmetic Ingredient Review Assessments
532 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Informational

Expand content Collapse content
CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Multiple, additive exposure sources

Expand content Collapse content
CONCERN REFERENCE
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

Can’t find your product?

Enter the ingredients in EWG’s Build Your Own Report tool to get an approximate score for that product.

BUILD YOUR OWN REPORT

EWG research
on the go

Find personal care, cleaning, and food products on the EWG Healthy Living app.

DOWNLOAD THE APP