Other ConcernsPersistence and bioaccumulation (moderate) and Non-reproductive organ system toxicity (moderate)
Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation
Poloxamer 124 is a polyoxyethylene, polyoxypropylene block polymer.
See how this product scores for common concerns.
LOWAllergies & Immunotoxicity
LOWDevelopmental and Reproductive Toxicity
- DATA SOURCES
Products with this Ingredient
Persistence and bioaccumulation
|Persistent or bioaccumulative and moderate to high toxicity concern in humans||Environment Canada Domestic Substance List|
|Not suspected to be bioaccumulative||Environment Canada Domestic Substance List|
Organ system toxicity (non-reproductive)
|Classified as expected to be toxic or harmful||Environment Canada Domestic Substance List|
|Classified as medium human health priority||Environment Canada Domestic Substance List|
|Suspected to be an environmental toxin||Environment Canada Domestic Substance List|
|Missing safety data noted by cosmetic industry review||Cosmetic Ingredient Review Assessments|
|Safety assessment was based on related chemical||Cosmetic Ingredient Review Assessments|
|524 studies in PubMed science library may include information on the toxicity of this chemical||NLM PubMed|
Multiple, additive exposure sources
|Designated as safe for general or specific, limited use in food||FDA Everything Added to Food|
|Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - any||Cosmetic Ingredient Review Assessments|
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.
Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.HOW WE DETERMINE SCORES
The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.
The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.