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HOW WE DETERMINE SCORES Learn more About EWG VERIFIED™

Data: Fair

Cetrimonium Methosulfate

IMAGE SOURCE: PubChem

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Other Concerns

Use restrictions (low), Neurotoxicity (low), Endocrine disruption (low), Non-reproductive organ system toxicity (moderate), and Irritation (skin, eyes, or lungs) (low)

SYNONYMS

1-HEXADECANAMINIUM, N,N,N-TRIMETHYL-, METHYL SULFATE, 1HEXADECANAMINIUM, N,N,NTRIMETHYL, METHYL SULFATE, AMMONIUM, HEXADECYLTRIMETHYL, METHYL SULFATE, CETRIMONIUM METHOSULFATE, CETYLTRIMETHYLAMMONIUM METHYL SULFATE, HEXADECYLTRIMETHYLAMMONIUM METHOSULFATE, HEXADECYLTRIMETHYLAMMONIUM METHYL SULPHATE, METHYL SULFATE 1-HEXADECANAMINIUM, N,N,N-TRIMETHYL-, N,N,N-TRIMETHYL- METHYL SULFATE 1-HEXADECANAMINIUM, and N,N,N-TRIMETHYL-1-HEXADECANAMINIUM METHYL SULFATE

Unacceptable

Unacceptable: EWG VERIFIED products cannot contain this ingredient

Cetrimonium Methosulfate is a quaternary ammonium salt.

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • HIGH
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • LOW
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

Expand content Collapse content
conditioner21 products
hair treatment/serum19 products
mask6 products
hair styling aide5 products
exfoliant/scrub2 products
1 products
facial moisturizer/treatment1 products

Allergies/immunotoxicity

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CONCERN REFERENCE
Known human any toxicant or allergenOpen scientific literature
Possible human any toxicant or allergenOpen scientific literature

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Possible human any toxicantOpen scientific literature
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Neurotoxicity

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CONCERN REFERENCE
One or more in vitro tests on mammalian cells demonstrate neurotoxicityOpen scientific literature

Developmental/reproductive toxicity

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CONCERN REFERENCE
One or more animal studies show any effects at moderate dosesOpen scientific literature

Irritation (skin, eyes, or lungs)

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CONCERN REFERENCE
any irritation - weight of evidence unknown/unassessedOpen scientific literature

Use restrictions

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CONCERN REFERENCE
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review Assessments

Endocrine disruption

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CONCERN REFERENCE
Associated with endocrine disruptionOpen scientific literature

Ecotoxicology

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CONCERN REFERENCE
Suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data gaps

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CONCERN REFERENCE
1423 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed
  • Open scientific/peer reviewed literature
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend
WEIGHT-OF-EVIDENCE APPROACH

A product’s hazard score is not an average of the ingredients’ hazard scores. It is calculated using a weight-of-evidence approach that factors in all of the hazards or health impacts associated with the ingredients.

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability
NONE

Ingredients have not been assessed.

LIMITED-FAIR

There is only a modest volume of research.

GOOD-ROBUST

Ingredients have been studied extensively.

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