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ACETYL HEXAMETHYL INDAN

Score:

Data: Good

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (high), Endocrine disruption (moderate), Persistence and bioaccumulation (moderate), and Irritation (skin, eyes, or lungs) (moderate)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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hair spray3 products

Use restrictions

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Concern Reference
Restricted in European cosmeticsEU Cosmetics Directive 2015. CosIng. Appears as: listid: COSING-31580; Chemical_Name: ACETYL HEXAMETHYL INDAN; ; CAS: 15323-35-0
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - anyCosIng
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn)IFRA_Standard_3html

Persistence and bioaccumulation

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Concern Reference
Persistent, bioaccumulative in wildlifeEmerging PBTs from peer-reviewed literature
Not suspected to be persistentEnvironment Canada Domestic Substance List

Endocrine disruption

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Concern Reference
The California Biomonitoring Program reports synthetic polycyclic musks as possible endocrine disruptorsCalifornia Environmental Contaminant Biomonitoring Program 2013. Synthetic Polycyclic Musks Materials for November 14, 2013 Meeting of Scientific Guidance Panel (SGP) Biomonitoring California.

Irritation (skin, eyes, or lungs)

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Concern Reference
Restriction recommended due to evidence of photoirrition in animals.International Fragrance Association (IFRA) 2015. IFRA Codes & Standards. Appears as: listid: IFRA-008; Chemical_Name: 5-Acetyl-1,1,2,3,3,6-hexamethyl indan (AHMI); Synonyms: Acetyl hexamethyl indan; 6-Acetyl-1,1,2,3,3,5-hexamethylindane; 1-(2,3-Dihydro-1,1,2,3,3,6-hexamethyl-1h-inden-5-yl)ethanone; Ethanone,1-(2,3-dihydro-1,1,2,3,3,6-hexamethyl-1H-inden-5-yl)-; 1,1,2,3,3,6-Hexamethylindan-5-yl Methylketone; Phantolid; CAS: 15323-35-0; Classification: Restricted

Ecotoxicology

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Concern Reference
The California Biomonitoring Program reports synthetic polycyclic musks as having environmental toxicity. California Environmental Contaminant Biomonitoring Program 2013. Synthetic Polycyclic Musks Materials for November 14, 2013 Meeting of Scientific Guidance Panel (SGP) Biomonitoring California.
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
10829 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Data Sources

  • EU Cosmetics Directive 2015. CosIng. Appears as: listid: COSING-31580; Chemical_Name: ACETYL HEXAMETHYL INDAN; ; CAS: 15323-35-0
  • European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
  • IFRA_Standard_3html
  • Emerging PBTs from peer-reviewed literature
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • California Environmental Contaminant Biomonitoring Program 2013. Synthetic Polycyclic Musks Materials for November 14, 2013 Meeting of Scientific Guidance Panel (SGP) Biomonitoring California.
  • International Fragrance Association (IFRA) 2015. IFRA Codes & Standards. Appears as: listid: IFRA-008; Chemical_Name: 5-Acetyl-1,1,2,3,3,6-hexamethyl indan (AHMI); Synonyms: Acetyl hexamethyl indan; 6-Acetyl-1,1,2,3,3,5-hexamethylindane; 1-(2,3-Dihydro-1,1,2,3,3,6-hexamethyl-1h-inden-5-yl)ethanone; Ethanone,1-(2,3-dihydro-1,1,2,3,3,6-hexamethyl-1H-inden-5-yl)-; 1,1,2,3,3,6-Hexamethylindan-5-yl Methylketone; Phantolid; CAS: 15323-35-0; Classification: Restricted
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

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