VITAMIN E SUCCINATE
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
|facial moisturizer/treatment||10 products|
|serums & essences||7 products|
|facial cleanser||5 products|
|facial powder||5 products|
|around-eye cream||3 products|
|lip balm||1 products|
|moisturizer with SPF||1 products|
|hand cream||1 products|
|sunless tanning||1 products|
|Subcutaneously injection of Vitamin E induced formation of fast growing fibrosarcomata at the site of the injection||Constantinides P, Harkey M 1985. Initiation of a transplantable fibrosarcoma by the synergism of two non-initiators, alpha-tocopherol and soya oil. Virchows Arch A Pathol Anat Histopathol 405(3): 285-97.|
|Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product||Cosmetic Ingredient Review Assessments|
|369 studies in PubMed science library may include information on the toxicity of this chemical||NLM PubMed|
|Uncertain environmental toxin and uncertain persistent or bioaccumulative||Environment Canada Domestic Substance List|
Multiple, additive exposure sources
|Designated as safe for general or specific, limited use in food||FDA Everything Added to Food|
|Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - any||Cosmetic Ingredient Review Assessments|
Organ system toxicity (non-reproductive)
|Classified as not expected to be potentially toxic or harmful||Environment Canada Domestic Substance List|
Persistence and bioaccumulation
|Not suspected to be persistent||Environment Canada Domestic Substance List|
|Not suspected to be bioaccumulative||Environment Canada Domestic Substance List|
- Constantinides P, Harkey M 1985. Initiation of a transplantable fibrosarcoma by the synergism of two non-initiators, alpha-tocopherol and soya oil. Virchows Arch A Pathol Anat Histopathol 405(3): 285-97.
- CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
ABOUT THE SKIN DEEP® RATINGS
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
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