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SULISOBENZONE

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Enhanced skin absorption, Endocrine disruption (low), Non-reproductive organ system toxicity (low), and Irritation (skin, eyes, or lungs) (moderate)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

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liquid hand soap106 products
shampoo75 products
body wash/cleanser55 products
conditioner46 products
hair styling aide36 products
styling gel/lotion27 products
moisturizer26 products
hand sanitizer25 products
facial cleanser22 products
after sun product19 products
hair treatment/serum18 products
hair spray14 products
mask14 products
body spray12 products
bath oil/salts/soak11 products
toners/astringents10 products
bubble bath10 products
styling mousse/foam10 products
facial moisturizer/treatment9 products
hand cream8 products
makeup primer7 products
exfoliant/scrub6 products
makeup remover5 products
body firming lotion4 products
serums & essences3 products
hair color and bleaching3 products
hair-loss treatment3 products
detangler2 products
fragrance for women2 products
eye makeup remover2 products
baby shampoo2 products
baby soap2 products
setting powder/spray1 products
1 products
shaving cream (men's)1 products
fragrance for men1 products
bar soap1 products
nail treatment1 products
damaged skin treatment1 products
around-eye cream1 products

Enhanced skin absorption

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Concern Reference
Penetration enhancerOpen scientific literature
Absorbs into the skinOpen scientific literature

Allergies/immunotoxicity

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Concern Reference
Human skin toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments
Human skin toxicant or allergen - strong evidenceEWG Assessment of Open Scientific Literature
One or more human case studies show possible photoallergic or allergenic effectsOpen scientific literature
One or more human case studies show equivocal photoallergic or allergenic effectsOpen scientific literature

Irritation (skin, eyes, or lungs)

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Concern Reference
Human any irritant - strong evidenceCosmetic Ingredient Review Assessments
Not likely to be a skin irritant in humansOpen scientific literature

Organ system toxicity (non-reproductive)

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Concern Reference
One or more animal studies show sense effects at moderate doses (low dose studies may be unavailable for this ingredient)Open scientific literature
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)Open scientific literature
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Endocrine disruption

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Concern Reference
Associated with endocrine disruptionOpen scientific literature

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
13180 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Persistence and bioaccumulation

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Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List
Not suspected to be persistentEnvironment Canada Domestic Substance List

Cancer

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Concern Reference
Not likely to be mutagenic in humansOpen scientific literature

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Data Sources

  • Open scientific/peer reviewed literature
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • EWG Assessment of Open Scientific Literature
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

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