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Data: Good

Octoxynol 9

IMAGE SOURCE: PubChem

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Other Concerns

Use restrictions (low), Endocrine disruption (low), Non-reproductive organ system toxicity (moderate), Multiple, additive exposure sources (low), Irritation (skin, eyes, or lungs) (moderate), and Contamination concerns (high)

SYNONYMS

26-( 4-OCTYLPHENOXY)-3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, 26-(4-OCTYLPHENOXY)- 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, 26-(OCTYLPHENOXY)- 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, 26-(OCTYLPHENOXY)-3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, 26-(4-OCTYLPHENOXY)-, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, 26-(OCTYLPHENOXY)-, NONAETHYLENE GLYCOL OCTYLPHENYL ETHER, OCTOXYNOL-9, PEG-9 OCTYL PHENYL ETHER, POLY(OXY-1,2-ETHANEDIYL), .ALPHA.-[4-(1,1,3,3-TETRAMETHYLBUTYL)PHENYL]-.OMEGA.-HYDROXY-, POLY(OXY1,2ETHANEDIYL), α[4(1,1,3,3TETRAMETHYLBUTYL)PHENYL]ωHYDROXY, POLYETHYLENE GLYCOL 450 OCTYL PHENYL ETHER, POLYOXYETHYLENE (9) OCTYL PHENYL ETHER, and POLYOXYETHYLENE OCTYL PHENYL ETHER; P-(1,1,3,3-TETRAMETHYLBUTYL)PHENOL ETHOXYLATE

Unacceptable

Unacceptable: EWG VERIFIED products cannot contain this ingredient


Octoxynol-9 is an ethoxylated alkyl phenol.

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • MODERATE
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • LOW
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

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daily use with SPF1 products
conditioner1 products
hair treatment/serum1 products
styling gel/lotion1 products

Contamination concerns

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Allergies/immunotoxicity

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CONCERN REFERENCE
Human skin toxicant or allergen - strong evidenceEWG Assessment of Open Scientific Literature
Human skin toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments

Irritation (skin, eyes, or lungs)

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CONCERN REFERENCE
Human any irritant - strong evidenceCosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Classified as medium human health priorityEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

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CONCERN REFERENCE
Used in food or as an additive with limited or no toxicity information availableFDA Everything Added to Food

Cancer

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CONCERN REFERENCE
One or more human case studies show possible cancer findingsOpen scientific literature

Endocrine disruption

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CONCERN REFERENCE
Limited evidence of endocrine disruptionScorecard.org Toxicity Information
any - weight of evidence unknown/unassessed/unreview: published lit review or major tox studyOpen scientific literature

Use restrictions

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CONCERN REFERENCE
Determined safe for use in cosmetics, subject to concentration or use limitations - Restrictions on impurities recommended by industry safety panelCosmetic Ingredient Review Assessments

Ecotoxicology

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CONCERN REFERENCE
Suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data gaps

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CONCERN REFERENCE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
Safety assessment was based on related chemicalCosmetic Ingredient Review Assessments
16535 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List
Not suspected to be persistentEnvironment Canada Domestic Substance List

Informational

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CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments
  • EWG Assessment of Open Scientific Literature
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • Open scientific/peer reviewed literature
  • ED (Environmental Defense). 2006. Scorecard _ The Pollution Information Site. http://www.scorecard.org.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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