EWG Skin Deep® | What is MANGANESE

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Data: Good

Manganese

IMAGE SOURCE: PubChem

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Other Concerns

Neurotoxicity (high), Persistence and bioaccumulation (high), and Non-reproductive organ system toxicity (high)

SYNONYMS

MANGANESE, MANGANESE (TOTAL), MANGANESE, DISSOLVED, MANGANESE; MANGANESE METAL ALLOY, and MN

Unacceptable

Unacceptable: EWG VERIFIED products cannot contain this ingredient

Common concerns

See how this product scores for common concerns.

LOW

Cancer
LOW

Allergies & Immunotoxicity
MODERATE

Developmental and Reproductive Toxicity
LOW

Use Restrictions

Ingredient concerns

CONCERNS
DATA SOURCES

Products with this Ingredient

around-eye cream

1 products

Organ system toxicity (non-reproductive)

CONCERN	REFERENCE
Known human respiratory toxicant	EPA Hazardous Air Pollutants
Classified as medium human health priority	Environment Canada Domestic Substance List
Classified as expected to be toxic or harmful	Environment Canada Domestic Substance List
Limited evidence of respiratory toxicity	Scorecard.org Toxicity Information
Limited evidence of respiratory toxicity	National Library of Medicine HazMap
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)	EPA Toxic Release Inventory PBTs
reproductive - weight of evidence unknown/unassessed/unreview: published lit review or major tox study	National Library of Medicine HazMap

Neurotoxicity

CONCERN	REFERENCE
Known human nervous system toxicant	Open scientific literature
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study	National Library of Medicine HazMap

Persistence and bioaccumulation

CONCERN	REFERENCE
Persistent, bioaccumulative in wildlife and humans	National Library of Medicine HazMap
Persistent, bioaccumulative in wildlife	National Library of Medicine HazMap
Not suspected to be bioaccumulative	Environment Canada Domestic Substance List

Developmental/reproductive toxicity

CONCERN	REFERENCE
Limited evidence of reproductive toxicity	National Library of Medicine HazMap
Limited evidence of reproductive toxicity	Scorecard.org Toxicity Information

Data gaps

CONCERN	REFERENCE
Insufficient data to determine safety	EPA Integrated Risk Information System (IRIS)
61205 studies in PubMed science library may include information on the toxicity of this chemical	NLM PubMed

Ecotoxicology

CONCERN	REFERENCE
Not suspected to be an environmental toxin	Environment Canada Domestic Substance List

Cancer

CONCERN	REFERENCE
Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gaps	EPA Integrated Risk Information System (IRIS)

EPA (U.S. Environmental Protection Agency). 2005. Office of Air. The 112(b)1 Hazardous Air Pollutants List (as modified). Last modified: 12 Dec 2005.
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
ED (Environmental Defense). 2006. Scorecard _ The Pollution Information Site. http://www.scorecard.org.
NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
Open scientific/peer reviewed literature
EPA (U.S. Environmental Protection Agency). 2008. Integrated Risk Information System (IRIS). Evidence for human carcinogenicity based on 1986-2005 guidelines.
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST

Low Availability

Moderate Availability

High Availability