Other Concerns
Enhanced skin absorption, Non-reproductive organ system toxicity (moderate), Irritation (skin, eyes, or lungs) (high), and Occupational hazards (moderate)SYNONYMS
This ingredient is not currently on EWG's Skin Deep Restricted or Unacceptable Lists.
Isopropyl alcohol is a common solvent.
Common concerns
See how this product scores for common concerns.
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LOWCancer
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LOWAllergies & Immunotoxicity
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LOWDevelopmental and Reproductive Toxicity
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LOWUse Restrictions
Ingredient concerns
- CONCERNS
- DATA SOURCES
Products with this Ingredient
| nail polish | 716 products |
| conditioner | 368 products |
| hair color and bleaching | 161 products |
| hair treatment/serum | 128 products |
| hand sanitizer | 82 products |
| shampoo | 66 products |
| mask | 42 products |
| hair styling aide | 37 products |
| nail treatment | 35 products |
| lip gloss | 29 products |
| mascara | 25 products |
| moisturizer | 17 products |
| styling gel/lotion | 15 products |
| hair spray | 13 products |
| exfoliant/scrub | 12 products |
| body wash/cleanser | 9 products |
| facial cleanser | 9 products |
| serums & essences | 7 products |
| detangler | 7 products |
| body firming lotion | 6 products |
| polish remover | 6 products |
| nail glue | 5 products |
| after sun product | 5 products |
| body oil | 5 products |
| facial moisturizer/treatment | 5 products |
| toners/astringents | 5 products |
| foot moisturizer | 5 products |
| BB cream | 4 products |
| 4 products | |
| after shave | 4 products |
| foot cleansing | 3 products |
| styling mousse/foam | 3 products |
| hand cream | 3 products |
| makeup primer | 3 products |
| bath oil/salts/soak | 3 products |
| bar soap | 2 products |
| around-eye cream | 2 products |
| hair-loss treatment | 2 products |
| eye liner | 2 products |
| beard cleanser | 2 products |
| foundation | 2 products |
| liquid hand soap | 2 products |
| lipstick | 1 products |
| daily use with SPF | 1 products |
| CC cream | 1 products |
| beard care | 1 products |
| brow liner | 1 products |
| makeup remover | 1 products |
| shaving cream (men's) | 1 products |
| setting powder/spray | 1 products |
| concealer | 1 products |
| antiperspirant/deodorant | 1 products |
| toothpaste | 1 products |
| anti-aging | 1 products |
| eyelash glue | 1 products |
| eye makeup remover | 1 products |
Enhanced skin absorption
| CONCERN | REFERENCE |
|---|---|
| Penetration enhancer | Open scientific literature |
Irritation (skin, eyes, or lungs)
| CONCERN | REFERENCE |
|---|---|
| Classified as any irritant | Open scientific literature |
Occupational hazards
| CONCERN | REFERENCE |
|---|---|
| Moderate evidence of occupational hazards | Open scientific literature |
| Limited evidence of occupational hazards | Open scientific literature |
Organ system toxicity (non-reproductive)
| CONCERN | REFERENCE |
|---|---|
| Classified as medium human health priority | Environment Canada Domestic Substance List |
| Classified as expected to be toxic or harmful | Environment Canada Domestic Substance List |
| Classified as toxic or harmful. | Open scientific literature |
| One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) | EPA Toxic Release Inventory PBTs |
| Associated with any toxicity | Open scientific literature |
Allergies/immunotoxicity
| CONCERN | REFERENCE |
|---|---|
| Limited evidence of any toxicity or allergies | Open scientific literature |
Data gaps
| CONCERN | REFERENCE |
|---|---|
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | Cosmetic Ingredient Review Assessments |
| 112675 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Miscellaneous
| CONCERN | REFERENCE |
|---|---|
| Occupational hazards related to handling | CPS&Q - Classification & Labelling |
Informational
| CONCERN | REFERENCE |
|---|---|
| Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - any | Cosmetic Ingredient Review Assessments |
Multiple, additive exposure sources
| CONCERN | REFERENCE |
|---|---|
| Designated as safe for general or specific, limited use in food | FDA Everything Added to Food |
Cancer
| CONCERN | REFERENCE |
|---|---|
| Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gaps | Int'l Agency for Research on Cancer (IARC) - Carcinogens |
Ecotoxicology
| CONCERN | REFERENCE |
|---|---|
| Not suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Neurotoxicity
| CONCERN | REFERENCE |
|---|---|
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | National Library of Medicine HazMap |
Persistence and bioaccumulation
| CONCERN | REFERENCE |
|---|---|
| Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
- Open scientific/peer reviewed literature
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
- CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
- FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
- IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
- NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
Understanding scores
Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.
Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.
HOW WE DETERMINE SCORESHazard score
The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.
Data availability
The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.