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Data: Limited

Guaiazulene

  • This ingredient’s score is higher if used in products intended for use around the eyes due to increased risk of absorption.
  • This ingredient’s score is higher if used in products intended for use on lips due to increased risk of ingestion and absorption.

IMAGE SOURCE: PubChem

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Other Concerns

Use restrictions (high), Non-reproductive organ system toxicity (moderate), and Ecotoxicology (low)

SYNONYMS

1,4-DIMETHYL-7-(1-METHYLETHYL)- AZULENE, 1,4-DIMETHYL-7-(1-METHYLETHYL)AZULENE, 1,4-DIMETHYL-7-ISOPROPYL-AZULENE, 7-ISOPROPYL-1,4-DIMETHYLAZULENE, AZULENE, 1,4-DIMETHYL-7-(1-METHYLETHYL)-, AZULENE, 1,4DIMETHYL7(1METHYLETHYL), and GUAIAZULENE

Guaiazulene is a color additive.

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reingredientive Toxicity
  • HIGH
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

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facial moisturizer/treatment3 products
facial cleanser3 products
mask2 products
around-eye cream1 products
toners/astringents1 products
antiperspirant/deodorant (men's)1 products

Use restrictions

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CONCERN REFERENCE
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive not approved by FDA for cosmetics used around eyesFDA Color Additive Status
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - anyOpen scientific literature

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List

Ecotoxicology

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CONCERN REFERENCE
Suspected to be an environmental toxin and be persistent or bioaccumulativeEnvironment Canada Domestic Substance List
Suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data gaps

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CONCERN REFERENCE
93 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Informational

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CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color additive approved by FDA for use in cosmeticsFDA Color Additive Status
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives - Exempt from Batch Certification by the U.S. Food and Drug AdministrationCTFA International Cosmetic Ingredient Dictionary and Handbook

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be persistentEnvironment Canada Domestic Substance List
  • FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
  • Open scientific/peer reviewed literature
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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