Menu Close Menu

Menu

GLUTARAL

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (low), Non-reproductive organ system toxicity (low), Ecotoxicology (low), and Occupational hazards (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

Expand content Collapse content
facial cleanser1 products
conditioner1 products

Use restrictions

Expand content Collapse content
Concern Reference
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR)Cosmetic Ingredient Review Assessments
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review Assessments

Occupational hazards

Expand content Collapse content
Concern Reference
Allowed workplace exposures restricted to low dosesCPS&Q - Classification & Labelling
Single case study detailing occupational hazardsNational Library of Medicine HazMap
Single case study detailing occupational hazardsFrazier , L and M. L. Hage (eds.). Reproductive Hazards of the Workplace, Wiley Europe, 1998. Table 10 (Partial List of Reproductive Toxicants) available at http://www.pharmacy.ohio-state.edu/homepage/safety/chemhygiene_table_repro.pdf.

Allergies/immunotoxicity

Expand content Collapse content
Concern Reference
Human immune and respiratory toxicant or allergen - strong evidenceAssociation of Occupational and Environmental Clinics
Human skin toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments
Human skin toxicant or allergen - strong evidenceEWG Assessment of Open Scientific Literature
Limited evidence of immune system toxicity or allergiesCPS&Q - Classification & Labelling

Organ system toxicity (non-reproductive)

Expand content Collapse content
Concern Reference
Classified as toxic or harmfulCPS&Q - Classification & Labelling
Limited evidence of respiratory toxicityA Relational Database of Hazardous Chemicals and Occupational Diseases Browse Haz-Map by Adverse Effects http://hazmap.nlm.nih.gov/hazmapadv.html, California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document 'Determination of Noncancer Chronic Reference Exposure Levels'. Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (http://www.oehha.ca.gov/air/chronic_rels/AllChrels.html, plus draft CRELS proposed through March 2004 (http://www.oehha.ca.gov/air/chronic_rels/index.html., National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation.
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Ecotoxicology

Expand content Collapse content
Concern Reference
Wildlife and environmental toxicityCPS&Q - Classification & Labelling
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Miscellaneous

Expand content Collapse content
Concern Reference
Occupational hazards related to handlingCPS&Q - Classification & Labelling

Data gaps

Expand content Collapse content
Concern Reference
Safety unknown for products left on skinCosmetic Ingredient Review Assessments
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
6227 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Multiple, additive exposure sources

Expand content Collapse content
Concern Reference
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

Expand content Collapse content
Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR)Cosmetic Ingredient Review Assessments

Persistence and bioaccumulation

Expand content Collapse content
Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
  • NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
  • Frazier , L and M. L. Hage (eds.). Reproductive Hazards of the Workplace, Wiley Europe, 1998. Table 10 (Partial List of Reproductive Toxicants) available at http://www.pharmacy.ohio-state.edu/homepage/safety/chemhygiene_table_repro.pdf.
  • AOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
  • EWG Assessment of Open Scientific Literature
  • A Relational Database of Hazardous Chemicals and Occupational Diseases Browse Haz-Map by Adverse Effects http://hazmap.nlm.nih.gov/hazmapadv.html, California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document 'Determination of Noncancer Chronic Reference Exposure Levels'. Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (http://www.oehha.ca.gov/air/chronic_rels/AllChrels.html, plus draft CRELS proposed through March 2004 (http://www.oehha.ca.gov/air/chronic_rels/index.html., National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

About this Ingredient's Score Range

  • This ingredient’s score is higher if used in products that will not be immediately rinsed off due to increased risk of absorption.
  • This ingredient’s score is higher if used in products that are inhalable (e.g., sprays, powders) because of respiratory concerns.
  • This ingredient’s score is higher if used in products intended for use around mouth due to increased risk of ingestion and absorption.
  • This ingredient’s score is higher if used in products intended for use on lips due to increased risk of ingestion and absorption.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

ABOUT EWG VERIFIED™

Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer