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CHLORHEXIDINE DIHYDROCHLORIDE
Score:
Data: Fair
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Use restrictions (moderate) and Irritation (skin, eyes, or lungs) (low)
Cancer 
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
| conditioner | 22 products |
| hair color and bleaching | 14 products |
| detangler | 5 products |
| shampoo | 4 products |
| hair treatment/serum | 3 products |
| hair relaxer | 3 products |
| hair styling aide | 2 products |
Allergies/immunotoxicity
| Concern | Reference |
|---|---|
| Human immune and respiratory toxicant or allergen - strong evidence | Association of Occupational and Environmental Clinics |
| Asthmagen sensitizer [Asthmagen, sensitizer induced according to Review by the Association of Occupational and Environmental Clinics (AOEC)] | AOEC (Association of Occupational and Environmental Clinics) 2012. Asthmagen compilation - AEOC exposures codes. |
| Limited evidence of immune system toxicity or allergies | National Library of Medicine HazMap |
Use restrictions
| Concern | Reference |
|---|---|
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | Canada - Prohibited and Restricted Cosmetics Ingredients |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit) | Japan's Standards for Cosmetics |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | JACT 12(3):201-23, 1993 IJT 18(2):69, 1999 (Note) |
Irritation (skin, eyes, or lungs)
| Concern | Reference |
|---|---|
| Limited evidence of skin irritation | National Library of Medicine HazMap |
Data gaps
| Concern | Reference |
|---|---|
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | JACT 12(3):201-23, 1993 IJT 18(2):69, 1999 (Note) |
| 6264 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Multiple, additive exposure sources
| Concern | Reference |
|---|---|
| Designated as safe for general or specific, limited use in food | FDA Food Additive Status |
Data Sources
- AOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
- AOEC (Association of Occupational and Environmental Clinics) 2012. Asthmagen compilation - AEOC exposures codes.
- NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
- Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
- Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau.
- JACT 12(3):201-23, 1993 IJT 18(2):69, 1999 (Note)
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
ABOUT THE SKIN DEEP® RATINGS
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
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