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BUTYL ALCOHOL
Score:
Data: Fair
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Use restrictions (moderate), Non-reproductive organ system toxicity (moderate), Irritation (skin, eyes, or lungs) (moderate), and Occupational hazards (high)
Cancer 
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
| nail polish | 138 products |
| nail treatment | 1 products |
| eye shadow | 1 products |
Irritation (skin, eyes, or lungs)
| Concern | Reference |
|---|---|
| Classified as lung and skin irritant | CPS&Q - Classification & Labelling |
| Human any irritant - strong evidence | IJT 27(S2): 53-69, 2008; JACT 6(3):403-25, 1987 (Original Report) |
Organ system toxicity (non-reproductive)
| Concern | Reference |
|---|---|
| Known human lung and skin toxicant | CPS&Q - Classification & Labelling |
| Classified as expected to be toxic or harmful | Environment Canada Domestic Substance List |
| Limited evidence of sense organ toxicity | Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria)., National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation. |
| One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) | EPA Toxic Release Inventory PBTs |
Occupational hazards
| Concern | Reference |
|---|---|
| Allowed workplace exposures restricted to low doses | CPS&Q - Classification & Labelling |
Use restrictions
| Concern | Reference |
|---|---|
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | IJT 27(S2): 53-69, 2008; JACT 6(3):403-25, 1987 (Original Report) |
Data gaps
| Concern | Reference |
|---|---|
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | IJT 27(S2): 53-69, 2008; JACT 6(3):403-25, 1987 (Original Report) |
| Insufficient data to determine safety | EPA (US Environmental Protection Agency). Integrated Risk Information System (IRIS). Evidence for human carcinogenicity based on 1986 guidelines. |
| 8745 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Miscellaneous
| Concern | Reference |
|---|---|
| Occupational hazards related to handling | CPS&Q - Classification & Labelling |
Cancer
| Concern | Reference |
|---|---|
| Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gaps | EPA (US Environmental Protection Agency). Integrated Risk Information System (IRIS). Evidence for human carcinogenicity based on 1986 guidelines. |
Multiple, additive exposure sources
| Concern | Reference |
|---|---|
| Designated as safe for general or specific, limited use in food | FDA Food Additive Status |
| Designated as safe for general or specific, limited use in food | IJT 27(S2): 53-69, 2008; JACT 6(3):403-25, 1987 (Original Report) |
| Designated as safe for general or specific, limited use in food | FDA Everything Added to Food |
Informational
| Concern | Reference |
|---|---|
| Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - any | IJT 27(S2): 53-69, 2008; JACT 6(3):403-25, 1987 (Original Report) |
Neurotoxicity
| Concern | Reference |
|---|---|
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | National Library of Medicine HazMap |
Data Sources
- CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
- IJT 27(S2): 53-69, 2008; JACT 6(3):403-25, 1987 (Original Report)
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria)., National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation.
- EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
- EPA (US Environmental Protection Agency). Integrated Risk Information System (IRIS). Evidence for human carcinogenicity based on 1986 guidelines.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
- FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
- NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
- This ingredient’s score is higher if used in products that are inhalable (e.g., sprays, powders) because of respiratory concerns.
- This ingredient’s score is higher if used in products intended for use around the eyes due to increased risk of absorption.
- Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data.
ABOUT THE SKIN DEEP® RATINGS
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
ABOUT EWG VERIFIED™
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer
