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TITANIUM DIOXIDE

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COMMONLY FOUND IN


SYNONYMS

TITANIUM(IV) OXIDE, RUTILE, &#60;110&#62;, SINGLE CRYSTAL SUBSTRATE, 99.99% TRACE METALS BASIS, L X W X THICKNESS 10 MM X 10 MM X 0.5 MM, TITANIUM DIOXIDE, UNITED STATES PHARMACOPEIA (USP) REFERENCE STANDARD, TITANIUM(IV) OXIDE, PELLETS, DIAM. X THICKNESS 12.5 MM X 5.5 MM, TITANIUM OXIDE DISPERSION (ANATASE, 20 WT%, 5-30 NM) NANO IN WATER, TITANIUM(IV) OXIDE, ANATASE, NANOPOWDER, <25 NM PARTICLE SIZE, 99.7% TRACE METALS BASIS, TITANIUM(IV) OXIDE, NATURALLY OCCURRING MINERAL, GRAINS, APPROXIMATELY 0.06-0.19IN, TITANIUM(IV) OXIDE, RUTILE, NANOPOWDER, <100 NM PARTICLE SIZE, 99.5% TRACE METALS BASIS, TITANIUM(IV) OXIDE, CONTAINS 1% MN AS DOPANT, NANOPOWDER, <100 NM PARTICLE SIZE (BET), >=97%, TITANIUM(IV) OXIDE, MIXTURE OF RUTILE AND ANATASE, NANOPARTICLE, <250 NM PARTICLE SIZE (DLS), PASTE, 53-57 WT. % IN DIETHYLENE GLYCOL MONOBUTYL ETHER/ETHYLENE GLYCOL, 99.9% TRACE METALS BASIS, TITANIUM(IV) OXIDE, RUTILE, POWDER, <5 MUM, >=99.9% TRACE METALS BASIS


RESTRICTED

EWG VERIFIED products cannot contain this ingredient without adequate substantiation.

Common Concerns

See how this product scores for common concerns.

  • SOME
    Asthma / Respiratory
  • No Data
    Skin Allergies & Irritation
  • No Data
    Developmental & Reproductive Toxicity
  • SOME
    Cancer
  • No Data
    Environment


Top Scoring Factors

Evidence of cancer; respiratory effects; kidney and urinary effects


Ingredient concerns

  • CONCERNS
Health Issue Level of Concern Source
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Possibly carcinogenic to humans

moderate

International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)

A National Toxicology Program (NTP) study reports that this substance causes fibrosis of the heart in animals at high doses.

Only in: Food Scores®

moderate

1979. Bioassay of titanium dioxide for possible carcinogenicity. National Cancer Institute carcinogenesis technical report series 97, 1-123.

A National Toxicology Program (NTP) study reports that this substance causes male reproductive effects in animals at high doses.

Only in: Food Scores®

moderate

1979. Bioassay of titanium dioxide for possible carcinogenicity. National Cancer Institute carcinogenesis technical report series 97, 1-123.

The European Food Safety Authority concluded this substance had the potential to damage DNA.

Only in: Food Scores®

some

EFSA. 2021. Safety assessment of titanium dioxide (E171) as a food additive. EFSA Journal.

lower respiratory tract irritation

some

American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis

A peer-reviewed study reports that nanoparticles of this substance accumulate in and may damage the liver in animals at high doses.

Only in: Food Scores®

some

Jiangxue Wang, Guoqiang Zhou, Chunying Chen, Hongwei Yu, Tiancheng Wang, Yongmei Ma, Guang Jia, Yuxi Gao, Bai Li, Jin Sun, Yufeng Li, Fang Jiao, Yuliang Zhao & Zhifang Chai. 2007. Acute toxicity and biodistribution of different sized titanium dioxide particles in mice after oral administration. Toxicology letters 168(2), 176-85.

A peer-reviewed study reports that nanoparticles of this substance accumulate in and may damage the kidneys in animals at high doses.

Only in: Food Scores®

some

Jiangxue Wang, Guoqiang Zhou, Chunying Chen, Hongwei Yu, Tiancheng Wang, Yongmei Ma, Guang Jia, Yuxi Gao, Bai Li, Jin Sun, Yufeng Li, Fang Jiao, Yuliang Zhao & Zhifang Chai. 2007. Acute toxicity and biodistribution of different sized titanium dioxide particles in mice after oral administration. Toxicology letters 168(2), 176-85.

not classifiable as a human carcinogen

low

American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis



Understanding scores

EWG provides information on cleaning product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any.

HOW WE DETERMINE SCORES

Hazard score

The Healthy Cleaning ingredient hazard score, from A to F, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend


4

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