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ACID YELLOW 73 (UNCERTIFIED D&C YELLOW NO. 7 OR 8)

 

Unacceptable: EWG VERIFIED products cannot contain this ingredient.

Asthma/Respiratory
 
No Data, Some Concern
 
Skin Allergies &
Irritation
 
No Data, Some Concern
 
Developmental &
Reproductive Toxicity
 
Some Concern
 
Cancer
 
No Data, Some Concern
 
Environment
 
No Data, Some Concern
 
Top scoring factors: Evidence of developmental/endocrine/reproductive effects; damage to DNA; damage to vision
Acid Yellow 73 (Uncertified D&C Yellow No. 7 or 8) can be found in 3 products.
Print
 

Evidence

Health issue
 
Level of Concern
 
Source
A review article concludes this substance may be a develomental toxin based on evidence in humans and animals.
 
some
 
Raphael Alford, Haley M. Simpson, Josh Duberman, G. Craig Hill, Mikako Ogawa, Celeste Regino, Hisataka Kobayashi & Peter L. Choyke. 2009. Toxicity of organic fluorophores used in molecular imaging: literature review. Molecular imaging 8(6), 341-54.
NTP Toxcast scored 2.5-3.5
 
some
 
National Toxicology Program (NTP): EWG Toxcast Analysis
A study by the National Toxicology Program reports this substance was genotoxic in vitro.
 
some
 
B. C. Myhr & W. J. Caspary. 1991. Chemical mutagenesis at the thymidine kinase locus in L5178Y mouse lymphoma cells: results for 31 coded compounds in the National Toxicology Program. Environmental and molecular mutagenesis 18(1), 51-83.
A review article reports that adverse reactions to this substance have been reported in humans.
 
some
 
Ilyse S. Kornblau & Jaafar F. El-Annan. 1900. Adverse reactions to fluorescein angiography: A comprehensive review of the literature. Survey of ophthalmology 64(5), 679-693.
causes serious eye irritation
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
A peer-reviewed article reports that people with a history of drug allergy may have adverse reactions to this substance.
 
some
 
Zhaoan Su, Panpan Ye, Yan Teng, Lixia Zhang & Xiaohong Shu. 2012. Adverse reaction in patients with drug allergy history after simultaneous intravenous fundus fluorescein angiography and indocyanine green angiography. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 28(4), 410-3.
A peer-reviewed article reports that allergic reactions to this substance are observed in humans.
 
some
 
Dimitrios C. Kalogeromitros, Michael P. Makris, Xenophon S. Aggelides, Anagnostis I. Mellios, Fani C. Giannoula, Kyriaki A. Sideri, Alexander A. Rouvas & Panagiotis G. Theodossiadis. 2011. Allergy skin testing in predicting adverse reactions to fluorescein: a prospective clinical study. Acta ophthalmologica 89(5), 480-3.
Low acute oral toxicty.
 
low
 
Raphael Alford, Haley M. Simpson, Josh Duberman, G. Craig Hill, Mikako Ogawa, Celeste Regino, Hisataka Kobayashi & Peter L. Choyke. 2009. Toxicity of organic fluorophores used in molecular imaging: literature review. Molecular imaging 8(6), 341-54.

Impurities

Health issue
 
Level of Concern
 
Source
Impurity: LEAD
Very toxic to aquatic life
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: ARSENIC
Very toxic to aquatic life
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: ARSENIC
Very toxic to aquatic life with long lasting effects
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: MERCURY
Very toxic to aquatic life
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: MERCURY
Very toxic to aquatic life with long lasting effects
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: MERCURY
May damage the unborn child.
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: ARSENIC
Toxic if swallowed
Only in: Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: ARSENIC
Toxic if inhaled
Only in: Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: MERCURY
peripheral nervous system impairment
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: MERCURY
kidney damage
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: MERCURY
central nervous system impairment
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: LEAD
Harmful if swallowed
Only in: Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: LEAD
may cause cancer
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: ARSENIC
may cause cancer
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: RESORCINOL
Very toxic to aquatic life
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: RESORCINOL
Clear evidence of endocrine disruption in at least one animal study
 
some
 
EU Endocrine: EU Endocrine Disrupters
Impurity: LEAD
Known to cause reproductive toxicity (to females)
 
some
 
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
Impurity: LEAD
Known to cause reproductive toxicity (to males)
 
some
 
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
Impurity: LEAD
Known to cause reproductive toxicity
 
some
 
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
Impurity: LEAD
Very toxic to aquatic life with long lasting effects
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: LEAD
May damage the unborn child.
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: LEAD
Suspected of damaging fertility.
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: ARSENIC
Carcinogenic to humans
 
some
 
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Impurity: ARSENIC
Carcinogenic to humans
 
some
 
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer
Impurity: ARSENIC
Known To Be Human Carcinogen
 
some
 
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
Impurity: ARSENIC
The Agency for Toxic Substances and Disease Registry reports this substance damages the cardiovascular system.
 
some
 
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 2007. Toxicological Profile for Arsenic.
Impurity: ARSENIC
The Agency for Toxic Substances and Disease Registry reports this substance damages the immune system.
 
some
 
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 2007. Toxicological Profile for Arsenic.
Impurity: ARSENIC
The Agency for Toxic Substances and Disease Registry reports this substance causes damage to the skin.
 
some
 
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 2007. Toxicological Profile for Arsenic.
Impurity: ARSENIC
The Agency for Toxic Substances and Disease Registry reports this substance can damage the kidneys.
 
some
 
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 2007. Toxicological Profile for Arsenic.
Impurity: MERCURY
Causes damage to organs through prolonged or repeated exposure
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: MERCURY
Fatal if inhaled
Only in: Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: LEAD
Probably carcinogenic to humans
 
some
 
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer
Impurity: LEAD
Reasonably Anticipated To Be Human Carcinogen
 
some
 
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
Impurity: ARSENIC
Toxic if swallowed
Only in: Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: ARSENIC
Toxic if inhaled
Only in: Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: LEAD
peripheral nervous system impairment
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: LEAD
hematologic effects
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: ARSENIC
confirmed human carcinogen
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: ARSENIC
cancer
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: ARSENIC
lung cancer
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: MERCURY
kidney damage
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: MERCURY
central nervous system impairment
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: MERCURY
EPA's review of industry submitted toxicity data and the potential for human exposure concludes that this substance poses a high risk for human health.
 
some
 
Environmental Protection Agency (EPA): EPA Hazard-Based Prioritizations - Risks
Impurity: LEAD
Harmful if swallowed
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: LEAD
harmful in inhaled
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: RESORCINOL
Harmful if swallowed
Only in: Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: LEAD
Possibly carcinogenic to humans
 
some
 
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Impurity: LEAD
May cause damage to organs through prolonged or repeated exposure
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: LEAD
Harmful if inhaled
Only in: Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: ARSENIC
The Agency for Toxic Substances and Disease Registry reports this substance shows some evidence of damage to the developing fetus.
 
some
 
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 2007. Toxicological Profile for Arsenic.
Impurity: RESORCINOL
causes damage to organs
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: LEAD
may cause cancer
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: LEAD
may cause harm to breast-fed children
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: LEAD
may damage fertility or the unborn child
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: LEAD
causes damage to organs through prolonged or repeated exposure
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: MERCURY
Fatal if swallowed
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: MERCURY
fatal if inhaled
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: LEAD
confirmed animal carcinogen with unknown relevance to humans
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: PHTHALIC ACID
Causes skin irritation
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: ARSENIC
Causes serious eye damage
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: ARSENIC
Causes skin irritation
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: RESORCINOL
Causes skin irritation
Only in: Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: RESORCINOL
may cause damage to organs
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: PHTHALIC ACID
Harmful if swallowed
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: LEAD
harmful in inhaled
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: LEAD
may cause damage to organs through prolonged or repeated exposure
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: ARSENIC
may cause drowsiness or dizziness
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: RESORCINOL
skin irritation
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: PHTHALIC ACID
causes serious eye irritation
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: ARSENIC
causes serious eye irritation
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: RESORCINOL
May cause an allergic skin reaction
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: PHTHALIC ACID
may cause respiratory irritation
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: RESORCINOL
Causes serious eye irritation
Only in: Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: RESORCINOL
NTP Toxcast scored 1.5-2.5
 
some
 
National Toxicology Program (NTP): EWG Toxcast Analysis
Impurity: RESORCINOL
Causes serious eye damage
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: PHTHALIC ACID
Causes skin irritation
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: RESORCINOL
Not classifiable as to its carcinogenicity to humans
 
low
 
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Impurity: RESORCINOL
not classifiable as a human carcinogen
 
low
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: MERCURY
Not classifiable as to its carcinogenicity to humans
 
low
 
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Impurity: MERCURY
Not classifiable as to human carcinogenicity
 
low
 
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer
Impurity: MERCURY
not classifiable as a human carcinogen
 
low
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: RESORCINOL
This substance is Generally Recognized as Safe (GRAS) as a food additive by the US Food and Drug Administration
Only in: Household Cleaners
 
low
 
U.S. Food and Drug Administration (FDA): FDA - Priority based Assessment of Food Additive (PAFA)
 
 
About the ratings About the ratings
EWG provides information on cleaning product ingredients from the published scientific... continue reading →
EWG provides information on cleaning product ingredients from published scientific literature, to supplement incomplete data available from companies and the government. The ratings indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors that determine actual health risks, if any. (Hide)
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