EFSA notes there is equivocal evidence of genotoxiciy.
|
some
|
European Food Safety Authority (EFSA). 2009. Scientific Opinion on the re‐evaluation of Quinoline Yellow (E 104) as a food additive. EFSA Journal 7(11), 1329.
|
EFSA concludes there is limited evidence that Yellow 10 in a mixture with other synthetic colours and sodium benzoate has a "small and statistically significant effect on activity and attention in children selected from the general population".
|
some
|
European Food Safety Authority (EFSA). 2009. Scientific Opinion on the re‐evaluation of Quinoline Yellow (E 104) as a food additive. EFSA Journal 7(11), 1329.
|
EFSA finds that developmental effects have been observed in animal tests.
|
some
|
European Food Safety Authority (EFSA). 2009. Scientific Opinion on the re‐evaluation of Quinoline Yellow (E 104) as a food additive. EFSA Journal 7(11), 1329.
|
Very toxic to aquatic life
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Very toxic to aquatic life
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Very toxic to aquatic life with long lasting effects
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Very toxic to aquatic life
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Very toxic to aquatic life with long lasting effects
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Causes damage to organs through prolonged or repeated exposure
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Very toxic to aquatic life
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Very toxic to aquatic life with long lasting effects
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
May damage the unborn child.
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Suspected of causing genetic defects
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Suspected of causing cancer
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Causes damage to organs through prolonged or repeated exposure
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Known to cause cancer
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
Suspected of causing genetic defects
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
May cause cancer
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Causes damage to organs through prolonged or repeated exposure
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Very toxic to aquatic life
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Very toxic to aquatic life with long lasting effects
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Fatal if inhaled
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Suspected of damaging fertility.
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Suspected of damaging the unborn child.
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Carcinogenic to humans
|
some
|
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
|
Known To Be Human Carcinogen
|
some
|
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
|
Probably carcinogenic to humans
|
some
|
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer
|
Probably carcinogenic to humans
|
some
|
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
|
Probably carcinogenic to humans
|
some
|
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer
|
A review article reports equivocal evidence of genotoxicity, including in human cell assays.
|
some
|
Peer Reviewed Literature: Amchova, P., H. Kotolova & J. Ruda-Kucerova. 2015. Health safety issues of synthetic food colorants. Regulatory toxicology and pharmacology : RTP 73(3), 914-22.
|
Toxic if swallowed
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Toxic if inhaled
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Toxic if swallowed
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Toxic in contact with skin
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Toxic if inhaled
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
peripheral nervous system impairment
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
kidney damage
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
central nervous system impairment
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
kidney damage
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
suspected human carcinogen
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
A peer-reviewed study reports endocrine activity in cellular assays.
|
some
|
Patrick Tarnow, Catrin Zordick, Alex Bottke, Berit Fischer, Friederike Kühne, Tewes Tralau & Andreas Luch. 2020. Characterization of Quinoline Yellow Dyes As Transient Aryl Hydrocarbon Receptor Agonists. Chemical research in toxicology 33(3), 742-750.
|
may cause cancer
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
causes damage to organs through prolonged or repeated exposure
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
may cause cancer
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Suspected of damaging fertility or the unborn child
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
suspected of causing genetics defects
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
EFSA notes that Yellow 10 intolerance/sensitivity have been reported.
|
some
|
European Food Safety Authority (EFSA). 2009. Scientific Opinion on the re‐evaluation of Quinoline Yellow (E 104) as a food additive. EFSA Journal 7(11), 1329.
|
confirmed animal carcinogen with unknown relevance to humans
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
Known to cause reproductive toxicity (to females)
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
Known to cause reproductive toxicity (to males)
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
Known to cause reproductive toxicity
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
Very toxic to aquatic life
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Very toxic to aquatic life with long lasting effects
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
May damage the unborn child.
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Suspected of damaging fertility.
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Suspected of causing genetic defects
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Suspected of causing cancer
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Causes damage to organs through prolonged or repeated exposure
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Known to cause cancer
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
Carcinogenic to humans
|
some
|
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
|
Carcinogenic to humans
|
some
|
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer
|
Known To Be Human Carcinogen
|
some
|
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
|
The Agency for Toxic Substances and Disease Registry reports this substance damages the cardiovascular system.
|
some
|
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 2007. Toxicological Profile for Arsenic.
|
The Agency for Toxic Substances and Disease Registry reports this substance damages the immune system.
|
some
|
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 2007. Toxicological Profile for Arsenic.
|
The Agency for Toxic Substances and Disease Registry reports this substance causes damage to the skin.
|
some
|
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 2007. Toxicological Profile for Arsenic.
|
The Agency for Toxic Substances and Disease Registry reports this substance can damage the kidneys.
|
some
|
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 2007. Toxicological Profile for Arsenic.
|
Fatal if inhaled
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
May cause an allergic skin reaction
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
NTP Toxcast scored 1.5-2.5
|
some
|
National Toxicology Program (NTP): EWG Toxcast Analysis
|
Toxic in contact with skin
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
toxic if inhaled
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Toxic of swallowed
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Probably carcinogenic to humans
|
some
|
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer
|
Reasonably Anticipated To Be Human Carcinogen
|
some
|
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
|
Probably carcinogenic to humans
|
some
|
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
|
SCCS notes there is limited evidence of skin irritation.
|
some
|
European Commission, Scientific Committee on Consumer Safety (SCCS). 2004. OPINION OF THE SCIENTIFIC COMMITTEE ON COSMETIC PRODUCTS AND NON-FOOD PRODUCTS INTENDED FOR CONSUMERS Concerning Acid Yellow 3.
|
Toxic if swallowed
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Toxic in contact with skin
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Toxic if inhaled
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
peripheral nervous system impairment
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
hematologic effects
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
confirmed human carcinogen
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
cancer
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
lung cancer
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
kidney damage
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
central nervous system impairment
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
EPA's review of industry submitted toxicity data and the potential for human exposure concludes that this substance poses a high risk for human health.
|
some
|
Environmental Protection Agency (EPA): EPA Hazard-Based Prioritizations - Risks
|
Causes serious eye damage
Only in: Drain Opener/Clog Remover; Oven Cleaner; Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Harmful if swallowed
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
harmful in inhaled
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
may cause damage to organs through prolonged or repeated exposure
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Harmful if swallowed
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Harmful if swallowed
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
harmful in inhaled
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Harmful if swallowed
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Possibly carcinogenic to humans
|
some
|
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
|
May cause damage to organs through prolonged or repeated exposure
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Harmful if swallowed
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Harmful if inhaled
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
The Agency for Toxic Substances and Disease Registry reports this substance shows some evidence of damage to the developing fetus.
|
some
|
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 2007. Toxicological Profile for Arsenic.
|
may cause cancer
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
may cause harm to breast-fed children
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
may damage fertility or the unborn child
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
causes damage to organs through prolonged or repeated exposure
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
May cause an allergic skin reaction
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
suspected of causing genetics defects
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
may cause respiratory irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Suspected of damaging fertility or the unborn child
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
May cause an allergic skin reaction
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
may cause respiratory irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Fatal if swallowed
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
fatal if inhaled
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
may cause respiratory irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
confirmed animal carcinogen with unknown relevance to humans
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
May cause an allergic skin reaction
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Toxic in contact with skin
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
toxic if inhaled
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Toxic of swallowed
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Causes skin irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Causes skin irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Causes serious eye damage
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Causes skin irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Causes serious eye damage
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Causes skin irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Causes serious eye damage
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Causes serious eye damage
Only in: Drain Opener/Clog Remover; Oven Cleaner; Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Harmful if swallowed
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
harmful in inhaled
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
may cause damage to organs through prolonged or repeated exposure
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
may cause drowsiness or dizziness
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Harmful in contact with skin
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
causes serious eye irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
causes serious eye irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
causes serious eye irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
causes serious eye irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
causes serious eye irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
May cause an allergic skin reaction
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
may cause respiratory irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Causes skin irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
Causes serious eye damage
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
causes serious eye irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
SCCS notes there is limited evidence of eye irritation.
|
low
|
European Commission, Scientific Committee on Consumer Safety (SCCS). 2004. OPINION OF THE SCIENTIFIC COMMITTEE ON COSMETIC PRODUCTS AND NON-FOOD PRODUCTS INTENDED FOR CONSUMERS Concerning Acid Yellow 3.
|
Not classifiable as to its carcinogenicity to humans
|
low
|
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
|
Not classifiable as to human carcinogenicity
|
low
|
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer
|
Not known to cause asthma
|
low
|
Association of Occupational and Environmental Clinics (AOEC): AOEC Exposure Code List (2020 Update)
|
Not classifiable as to its carcinogenicity to humans
|
low
|
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
|
Not classifiable as to human carcinogenicity
|
low
|
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer
|
not classifiable as a human carcinogen
|
low
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
EPA testing shows this substance has moderate acute toxicity to aquatic life
|
low
|
Environmental Protection Agency (EPA): EPA Fathead Minnow Acute Toxicity Database
|
EPA testing shows this substance has low acute toxicity to aquatic life
|
low
|
Environmental Protection Agency (EPA): EPA Fathead Minnow Acute Toxicity Database
|
EPA testing shows this substance has moderate acute toxicity to aquatic life
|
low
|
Environmental Protection Agency (EPA): EPA Fathead Minnow Acute Toxicity Database
|
No evidence of skin sensitization in limited human and animal tests.
|
low
|
European Commission, Scientific Committee on Consumer Safety (SCCS). 2004. OPINION OF THE SCIENTIFIC COMMITTEE ON COSMETIC PRODUCTS AND NON-FOOD PRODUCTS INTENDED FOR CONSUMERS Concerning Acid Yellow 3.
|
EPA testing shows this substance has low acute toxicity to aquatic life
|
low
|
Environmental Protection Agency (EPA): EPA Fathead Minnow Acute Toxicity Database
|
Low acute oral toxicity in animal studies.
|
low
|
European Commission, Scientific Committee on Consumer Safety (SCCS). 2004. OPINION OF THE SCIENTIFIC COMMITTEE ON COSMETIC PRODUCTS AND NON-FOOD PRODUCTS INTENDED FOR CONSUMERS Concerning Acid Yellow 3.
|