Evidence
Health issue
Level of Concern
Source
Known to cause cancer
high
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
Known to cause cancer
high
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
SCCS concludes this substance impacts the immune system when inhaled.
moderate
European Commission, Scientific Committee on Consumer Safety (SCCS). 2015. Opinion on Carbon Black (nano-form).
SCCS concludes this substance may be carcinogenic when inhaled.
moderate
European Commission, Scientific Committee on Consumer Safety (SCCS). 2015. Opinion on Carbon Black (nano-form).
Possibly carcinogenic to humans
moderate
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Possibly carcinogenic to humans
moderate
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
confirmed animal carcinogen with unknown relevance to humans
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
confirmed animal carcinogen with unknown relevance to humans
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
SCCS concludes this substance may be genotoxic based on in vivo and in vitro evidence.
some
European Commission, Scientific Committee on Consumer Safety (SCCS). 2015. Opinion on Carbon Black (nano-form).
SCCS concludes this substance may be toxic to reproduction/development when inhaled.
some
European Commission, Scientific Committee on Consumer Safety (SCCS). 2015. Opinion on Carbon Black (nano-form).
bronchitis
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
bronchitis
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
A peer-reviewed study reports that maternal inhalation of this substance led to neurodevelopmental effects in offspring.
some
Masakazu Umezawa, Atsuto Onoda, Irina Korshunova, Alexander C. Ø Jensen, Ismo K. Koponen, Keld A. Jensen, Konstantin Khodosevich, Ulla Vogel & Karin S. Hougaard. 2018. Maternal inhalation of carbon black nanoparticles induces neurodevelopmental changes in mouse offspring. Particle and fibre toxicology 15(1), 36.
SCCS reports that inhalation of this substance impacted lung function in healthy humans.
some
European Commission, Scientific Committee on Consumer Safety (SCCS). 2015. Opinion on Carbon Black (nano-form).
SCCS concludes this substance is not an eye irritant.
low
European Commission, Scientific Committee on Consumer Safety (SCCS). 2015. Opinion on Carbon Black (nano-form).
SCCS concludes this substance is not a skin irritant.
low
European Commission, Scientific Committee on Consumer Safety (SCCS). 2015. Opinion on Carbon Black (nano-form).
Impurities
Health issue
Level of Concern
Source
Impurity: ARSENIC
Very toxic to aquatic life
Very toxic to aquatic life
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: ARSENIC
Very toxic to aquatic life with long lasting effects
Very toxic to aquatic life with long lasting effects
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: ARSENIC
Carcinogenic to humans
Carcinogenic to humans
some
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Impurity: ARSENIC
Known To Be Human Carcinogen
Known To Be Human Carcinogen
some
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
Impurity: LEAD
Very toxic to aquatic life
Very toxic to aquatic life
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: LEAD
Very toxic to aquatic life with long lasting effects
Very toxic to aquatic life with long lasting effects
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: MERCURY
Causes damage to organs through prolonged or repeated exposure
Causes damage to organs through prolonged or repeated exposure
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: MERCURY
Very toxic to aquatic life
Very toxic to aquatic life
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: MERCURY
Very toxic to aquatic life with long lasting effects
Very toxic to aquatic life with long lasting effects
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: MERCURY
Fatal if inhaled
Only in: Household Cleaners
Fatal if inhaled
Only in: Household Cleaners
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: MERCURY
May damage the unborn child.
May damage the unborn child.
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: POLYCYCLIC AROMATIC HYDROCARBONS (PAHS)
May cause cancer
May cause cancer
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: POLYCYCLIC AROMATIC HYDROCARBONS (PAHS)
Very toxic to aquatic life
Very toxic to aquatic life
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: POLYCYCLIC AROMATIC HYDROCARBONS (PAHS)
Very toxic to aquatic life with long lasting effects
Very toxic to aquatic life with long lasting effects
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: BENZO[A]PYRENE
May cause cancer
May cause cancer
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: BENZO[A]PYRENE
Very toxic to aquatic life
Very toxic to aquatic life
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: BENZO[A]PYRENE
Very toxic to aquatic life with long lasting effects
Very toxic to aquatic life with long lasting effects
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: BENZO[A]PYRENE
May damage the unborn child.
May damage the unborn child.
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: BENZO[A]PYRENE
Known to cause cancer
Known to cause cancer
some
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
Impurity: BENZO[A]PYRENE
Carcinogenic to humans
Carcinogenic to humans
some
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Impurity: CADMIUM
Suspected of causing genetic defects
Suspected of causing genetic defects
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
May cause cancer
May cause cancer
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Causes damage to organs through prolonged or repeated exposure
Causes damage to organs through prolonged or repeated exposure
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Very toxic to aquatic life
Very toxic to aquatic life
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Very toxic to aquatic life with long lasting effects
Very toxic to aquatic life with long lasting effects
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Fatal if inhaled
Only in: Household Cleaners
Fatal if inhaled
Only in: Household Cleaners
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Suspected of damaging fertility.
Suspected of damaging fertility.
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Suspected of damaging the unborn child.
Suspected of damaging the unborn child.
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Carcinogenic to humans
Carcinogenic to humans
some
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Impurity: CADMIUM
Known To Be Human Carcinogen
Known To Be Human Carcinogen
some
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
Impurity: BENZO[A]PYRENE
Probably carcinogenic to humans
Probably carcinogenic to humans
some
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer
Impurity: BENZO[A]PYRENE
Reasonably Anticipated To Be Human Carcinogen
Reasonably Anticipated To Be Human Carcinogen
some
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
Impurity: CADMIUM
Probably carcinogenic to humans
Probably carcinogenic to humans
some
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer
Impurity: ARSENIC
Toxic if swallowed
Only in: Household Cleaners
Toxic if swallowed
Only in: Household Cleaners
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: ARSENIC
Toxic if inhaled
Only in: Household Cleaners
Toxic if inhaled
Only in: Household Cleaners
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: MERCURY
peripheral nervous system impairment
peripheral nervous system impairment
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: MERCURY
kidney damage
kidney damage
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: MERCURY
central nervous system impairment
central nervous system impairment
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: BENZO[A]PYRENE
cancer
cancer
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: CADMIUM
kidney damage
kidney damage
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: BENZO[A]PYRENE
suspected human carcinogen
suspected human carcinogen
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: CADMIUM
suspected human carcinogen
suspected human carcinogen
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: LEAD
Possibly carcinogenic to humans
Possibly carcinogenic to humans
some
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Impurity: LEAD
may cause cancer
Only in: Household Cleaners
may cause cancer
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: LEAD
confirmed animal carcinogen with unknown relevance to humans
confirmed animal carcinogen with unknown relevance to humans
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: ARSENIC
Carcinogenic to humans
Carcinogenic to humans
some
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer
Impurity: ARSENIC
The Agency for Toxic Substances and Disease Registry reports this substance damages the cardiovascular system.
The Agency for Toxic Substances and Disease Registry reports this substance damages the cardiovascular system.
some
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 2007. Toxicological Profile for Arsenic.
Impurity: ARSENIC
The Agency for Toxic Substances and Disease Registry reports this substance damages the immune system.
The Agency for Toxic Substances and Disease Registry reports this substance damages the immune system.
some
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 2007. Toxicological Profile for Arsenic.
Impurity: ARSENIC
The Agency for Toxic Substances and Disease Registry reports this substance causes damage to the skin.
The Agency for Toxic Substances and Disease Registry reports this substance causes damage to the skin.
some
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 2007. Toxicological Profile for Arsenic.
Impurity: ARSENIC
The Agency for Toxic Substances and Disease Registry reports this substance can damage the kidneys.
The Agency for Toxic Substances and Disease Registry reports this substance can damage the kidneys.
some
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 2007. Toxicological Profile for Arsenic.
Impurity: LEAD
Known to cause reproductive toxicity (to females)
Known to cause reproductive toxicity (to females)
some
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
Impurity: LEAD
Known to cause reproductive toxicity (to males)
Known to cause reproductive toxicity (to males)
some
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
Impurity: LEAD
Known to cause reproductive toxicity
Known to cause reproductive toxicity
some
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
Impurity: LEAD
May damage the unborn child.
May damage the unborn child.
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: LEAD
Suspected of damaging fertility.
Suspected of damaging fertility.
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: BENZO[A]PYRENE
May cause genetic defects
May cause genetic defects
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: BENZO[A]PYRENE
May damage fertility.
May damage fertility.
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: BENZO[A]PYRENE
Clear evidence of endocrine disruption in at least one animal study
Clear evidence of endocrine disruption in at least one animal study
some
EU Endocrine: EU Endocrine Disrupters
Impurity: LEAD
Probably carcinogenic to humans
Probably carcinogenic to humans
some
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer
Impurity: LEAD
Reasonably Anticipated To Be Human Carcinogen
Reasonably Anticipated To Be Human Carcinogen
some
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
Impurity: ARSENIC
Toxic if swallowed
Only in: Household Cleaners
Toxic if swallowed
Only in: Household Cleaners
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: ARSENIC
Toxic if inhaled
Only in: Household Cleaners
Toxic if inhaled
Only in: Household Cleaners
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: ARSENIC
confirmed human carcinogen
confirmed human carcinogen
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: ARSENIC
cancer
cancer
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: ARSENIC
lung cancer
lung cancer
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: LEAD
peripheral nervous system impairment
peripheral nervous system impairment
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: LEAD
hematologic effects
hematologic effects
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: MERCURY
central nervous system impairment
central nervous system impairment
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: MERCURY
EPA's review of industry submitted toxicity data and the potential for human exposure concludes that this substance poses a high risk for human health.
EPA's review of industry submitted toxicity data and the potential for human exposure concludes that this substance poses a high risk for human health.
some
Environmental Protection Agency (EPA): EPA Hazard-Based Prioritizations - Risks
Impurity: BENZO[A]PYRENE
Exposure by all routes should be carefully controlled to levels as low as possible
Exposure by all routes should be carefully controlled to levels as low as possible
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: LEAD
Harmful if swallowed
Only in: Household Cleaners
Harmful if swallowed
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: LEAD
harmful in inhaled
Only in: Household Cleaners
harmful in inhaled
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: ARSENIC
The Agency for Toxic Substances and Disease Registry reports this substance shows some evidence of damage to the developing fetus.
The Agency for Toxic Substances and Disease Registry reports this substance shows some evidence of damage to the developing fetus.
some
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 2007. Toxicological Profile for Arsenic.
Impurity: LEAD
May cause damage to organs through prolonged or repeated exposure
May cause damage to organs through prolonged or repeated exposure
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: LEAD
Harmful if swallowed
Only in: Household Cleaners
Harmful if swallowed
Only in: Household Cleaners
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: LEAD
Harmful if inhaled
Only in: Household Cleaners
Harmful if inhaled
Only in: Household Cleaners
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: ARSENIC
may cause cancer
Only in: Household Cleaners
may cause cancer
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: LEAD
may cause harm to breast-fed children
Only in: Household Cleaners
may cause harm to breast-fed children
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: LEAD
may damage fertility or the unborn child
Only in: Household Cleaners
may damage fertility or the unborn child
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: LEAD
causes damage to organs through prolonged or repeated exposure
Only in: Household Cleaners
causes damage to organs through prolonged or repeated exposure
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: MERCURY
Fatal if swallowed
Only in: Household Cleaners
Fatal if swallowed
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: MERCURY
fatal if inhaled
Only in: Household Cleaners
fatal if inhaled
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: BENZO[A]PYRENE
May cause an allergic skin reaction
Only in: Household Cleaners
May cause an allergic skin reaction
Only in: Household Cleaners
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: SULFUR
Causes serious eye damage
Only in: Household Cleaners
Causes serious eye damage
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: SULFUR
Causes skin irritation
Only in: Household Cleaners
Causes skin irritation
Only in: Household Cleaners
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: ARSENIC
may cause drowsiness or dizziness
Only in: Household Cleaners
may cause drowsiness or dizziness
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: LEAD
Harmful if swallowed
Only in: Household Cleaners
Harmful if swallowed
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: LEAD
harmful in inhaled
Only in: Household Cleaners
harmful in inhaled
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: LEAD
may cause damage to organs through prolonged or repeated exposure
Only in: Household Cleaners
may cause damage to organs through prolonged or repeated exposure
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: SULFUR
may cause respiratory irritation
Only in: Household Cleaners
may cause respiratory irritation
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: ARSENIC
Causes serious eye damage
Only in: Household Cleaners
Causes serious eye damage
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: ARSENIC
Causes skin irritation
Only in: Household Cleaners
Causes skin irritation
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: ARSENIC
causes serious eye irritation
Only in: Household Cleaners
causes serious eye irritation
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: MERCURY
Not classifiable as to its carcinogenicity to humans
Not classifiable as to its carcinogenicity to humans
low
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Impurity: MERCURY
Not classifiable as to human carcinogenicity
Not classifiable as to human carcinogenicity
low
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer
Impurity: MERCURY
not classifiable as a human carcinogen
not classifiable as a human carcinogen
low
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
