Evidence
Health issue
Level of Concern
Source
European Union Ecolabel program data shows this substance has high chronic toxicity to aquatic life
some
Detergents Ingredients Database - EU Ecolabel
European Union Ecolabel program data shows this substance has very high acute toxicity to aquatic life
some
Detergents Ingredients Database - EU Ecolabel
European Union Ecolabel program data shows this substance has high acute toxicity to aquatic life
some
Detergents Ingredients Database - EU Ecolabel
A Cosmetic Ingredient Review safety assessment found ethoxylated alkyl sulfates like sodium laureth sulfate can irritate the skin.
some
Valerie C. Robinson, Paul W. Snyder, Thomas J. Slaga, Ronald C. Shank, James G. Marks, Curtis D. Klaassen, Ronald A. Hill, Donald V. Belsito, Wilma F. Bergfeld & F. Alan Andersen. 2010. Final report of the amended safety assessment of sodium laureth sulfate and related salts of sulfated ethoxylated alcohols. International journal of toxicology 29(4 Suppl), 151S-61S.
A Cosmetic Ingredient Review safety assessment found ethoxylated alkyl sulfates like sodium laureth sulfate do not cause skin sensitization.
low
Valerie C. Robinson, Paul W. Snyder, Thomas J. Slaga, Ronald C. Shank, James G. Marks, Curtis D. Klaassen, Ronald A. Hill, Donald V. Belsito, Wilma F. Bergfeld & F. Alan Andersen. 2010. Final report of the amended safety assessment of sodium laureth sulfate and related salts of sulfated ethoxylated alcohols. International journal of toxicology 29(4 Suppl), 151S-61S.
A Cosmetic Ingredient Review safety assessment found ethoxylated alkyl sulfates like sodium laureth sulfate have low acute oral toxicity.
low
Valerie C. Robinson, Paul W. Snyder, Thomas J. Slaga, Ronald C. Shank, James G. Marks, Curtis D. Klaassen, Ronald A. Hill, Donald V. Belsito, Wilma F. Bergfeld & F. Alan Andersen. 2010. Final report of the amended safety assessment of sodium laureth sulfate and related salts of sulfated ethoxylated alcohols. International journal of toxicology 29(4 Suppl), 151S-61S.
A Cosmetic Ingredient Review safety assessment found ethoxylated alkyl sulfates like sodium laureth sulfate are not toxic to reproduction or development.
low
Valerie C. Robinson, Paul W. Snyder, Thomas J. Slaga, Ronald C. Shank, James G. Marks, Curtis D. Klaassen, Ronald A. Hill, Donald V. Belsito, Wilma F. Bergfeld & F. Alan Andersen. 2010. Final report of the amended safety assessment of sodium laureth sulfate and related salts of sulfated ethoxylated alcohols. International journal of toxicology 29(4 Suppl), 151S-61S.
A Cosmetic Ingredient Review safety assessment found ethoxylated alkyl sulfates like sodium laureth sulfate do not cause skin cancer after repeated skin application.
low
Valerie C. Robinson, Paul W. Snyder, Thomas J. Slaga, Ronald C. Shank, James G. Marks, Curtis D. Klaassen, Ronald A. Hill, Donald V. Belsito, Wilma F. Bergfeld & F. Alan Andersen. 2010. Final report of the amended safety assessment of sodium laureth sulfate and related salts of sulfated ethoxylated alcohols. International journal of toxicology 29(4 Suppl), 151S-61S.
A Cosmetic Ingredient Review safety assessment found ethoxylated alkyl sulfates like sodium laureth sulfate have low acute oral toxicity.
low
Valerie C. Robinson, Paul W. Snyder, Thomas J. Slaga, Ronald C. Shank, James G. Marks, Curtis D. Klaassen, Ronald A. Hill, Donald V. Belsito, Wilma F. Bergfeld & F. Alan Andersen. 2010. Final report of the amended safety assessment of sodium laureth sulfate and related salts of sulfated ethoxylated alcohols. International journal of toxicology 29(4 Suppl), 151S-61S.
A Cosmetic Ingredient Review safety assessment found ethoxylated alkyl sulfates like sodium laureth sulfate are not toxic to reproduction or development.
low
Valerie C. Robinson, Paul W. Snyder, Thomas J. Slaga, Ronald C. Shank, James G. Marks, Curtis D. Klaassen, Ronald A. Hill, Donald V. Belsito, Wilma F. Bergfeld & F. Alan Andersen. 2010. Final report of the amended safety assessment of sodium laureth sulfate and related salts of sulfated ethoxylated alcohols. International journal of toxicology 29(4 Suppl), 151S-61S.
The European Union Ecolabel program reports this substance is readily biodegradable.
low
Detergents Ingredients Database - EU Ecolabel
The European Union Ecolabel program reports this substance is anaerobically degradable.
low
Detergents Ingredients Database - EU Ecolabel
The European Union Ecolabel program reports this substance is readily biodegradable.
low
Detergents Ingredients Database - EU Ecolabel
The European Union Ecolabel program reports this substance is anaerobically degradable.
low
Detergents Ingredients Database - EU Ecolabel
Impurities
Health issue
Level of Concern
Source
Impurity: ETHYLENE OXIDE
May cause genetic defects
May cause genetic defects
some
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: ETHYLENE OXIDE
May cause cancer
May cause cancer
some
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: ETHYLENE OXIDE
Known to cause cancer
Known to cause cancer
some
Prop 65 - CA Proposition 65
Impurity: ETHYLENE OXIDE
Known to cause reproductive toxicity (to females)
Known to cause reproductive toxicity (to females)
some
Prop 65 - CA Proposition 65
Impurity: ETHYLENE OXIDE
Known to cause reproductive toxicity
Known to cause reproductive toxicity
some
Prop 65 - CA Proposition 65
Impurity: ETHYLENE OXIDE
Known to cause reproductive toxicity (to males)
Known to cause reproductive toxicity (to males)
some
Prop 65 - CA Proposition 65
Impurity: ETHYLENE OXIDE
Carcinogenic to humans
Carcinogenic to humans
some
IARC 103 - IARC
Impurity: ETHYLENE OXIDE
Known To Be Human Carcinogen
Known To Be Human Carcinogen
some
NTP 12th RoC - National Toxicology Program (NTP)
Impurity: 1,4-DIOXANE
Suspected of causing cancer
Suspected of causing cancer
some
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: 1,4-DIOXANE
Known to cause cancer
Known to cause cancer
some
Prop 65 - CA Proposition 65
Impurity: 1,4-DIOXANE
Reasonably Anticipated To Be Human Carcinogen
Reasonably Anticipated To Be Human Carcinogen
some
NTP 12th RoC - National Toxicology Program (NTP)
Impurity: ETHYLENE OXIDE
Toxic if inhaled
Only in: Household Cleaners
Toxic if inhaled
Only in: Household Cleaners
some
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: ETHYLENE OXIDE
Asthmagen (irritation)
Asthmagen (irritation)
some
AOEC Asthmagen list - AOEC
Impurity: ETHYLENE OXIDE
Causes pulmonary edema
Causes pulmonary edema
some
NIOSH Pocket Guide to Chemical Hazards - Centers for Disease Control and Prevention (CDC)
Impurity: ETHYLENE OXIDE
Causes skin corrosion
Only in: Oven Cleaner; Drain Opener/Clog Remover
Causes skin corrosion
Only in: Oven Cleaner; Drain Opener/Clog Remover
some
NIOSH Pocket Guide to Chemical Hazards - Centers for Disease Control and Prevention (CDC)
Impurity: ETHYLENE OXIDE
Causes reproductive effects
Causes reproductive effects
some
NIOSH Pocket Guide to Chemical Hazards - Centers for Disease Control and Prevention (CDC)
Impurity: ETHYLENE OXIDE
Causes leukemia
Causes leukemia
some
NIOSH Pocket Guide to Chemical Hazards - Centers for Disease Control and Prevention (CDC)
Impurity: ETHYLENE OXIDE
Causes peritoneal cancer
Causes peritoneal cancer
some
NIOSH Pocket Guide to Chemical Hazards - Centers for Disease Control and Prevention (CDC)
Impurity: ETHYLENE OXIDE
cancer
cancer
some
Threshold Limit Value (TLV) Basis - American Conference of Governmental Industrial Hygienists (ACGIH)
Impurity: ETHYLENE OXIDE
central nervous system impairment
central nervous system impairment
some
Threshold Limit Value (TLV) Basis - American Conference of Governmental Industrial Hygienists (ACGIH)
Impurity: 1,4-DIOXANE
Causes cancer
Causes cancer
some
NIOSH Pocket Guide to Chemical Hazards - Centers for Disease Control and Prevention (CDC)
Impurity: 1,4-DIOXANE
liver damage
liver damage
some
Threshold Limit Value (TLV) Basis - American Conference of Governmental Industrial Hygienists (ACGIH)
Impurity: ETHYLENE OXIDE
suspected human carcinogen
suspected human carcinogen
some
Threshold Limit Value (TLV) Basis - American Conference of Governmental Industrial Hygienists (ACGIH)
Impurity: 1,4-DIOXANE
Possibly carcinogenic to humans
Possibly carcinogenic to humans
some
IARC 103 - IARC
Impurity: ETHYLENE OXIDE
Asthmagen
Asthmagen
some
AOEC Asthmagen list - AOEC
Impurity: 1,4-DIOXANE
confirmed animal carcinogen with unknown relevance to humans
confirmed animal carcinogen with unknown relevance to humans
some
Threshold Limit Value (TLV) Basis - American Conference of Governmental Industrial Hygienists (ACGIH)
Impurity: ETHYLENE OXIDE
May cause respiratory irritation
Only in: Household Cleaners
May cause respiratory irritation
Only in: Household Cleaners
some
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: 1,4-DIOXANE
May cause respiratory irritation
Only in: Household Cleaners
May cause respiratory irritation
Only in: Household Cleaners
some
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: ETHYLENE OXIDE
Causes skin irritation
Only in: Household Cleaners
Causes skin irritation
Only in: Household Cleaners
some
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: ETHYLENE OXIDE
Causes respiratory irritation
Causes respiratory irritation
some
NIOSH Pocket Guide to Chemical Hazards - Centers for Disease Control and Prevention (CDC)
Impurity: 1,4-DIOXANE
Causes respiratory irritation
Causes respiratory irritation
some
NIOSH Pocket Guide to Chemical Hazards - Centers for Disease Control and Prevention (CDC)
Impurity: ETHYLENE OXIDE
Harmful if swallowed
Only in: Household Cleaners
Harmful if swallowed
Only in: Household Cleaners
some
GHS Data from ECHA Website - European Chemicals Agency (ECHA)
Impurity: ETHYLENE OXIDE
Causes skin irritation
Causes skin irritation
some
NIOSH Pocket Guide to Chemical Hazards - Centers for Disease Control and Prevention (CDC)
Impurity: ETHYLENE OXIDE
Causes eye corrosion
Only in: Drain Opener/Clog Remover; Oven Cleaner
Causes eye corrosion
Only in: Drain Opener/Clog Remover; Oven Cleaner
some
NIOSH Pocket Guide to Chemical Hazards - Centers for Disease Control and Prevention (CDC)
Impurity: 1,4-DIOXANE
Causes skin irritation
Causes skin irritation
some
NIOSH Pocket Guide to Chemical Hazards - Centers for Disease Control and Prevention (CDC)
Impurity: ETHYLENE OXIDE
may cause respiratory irritation
Only in: Household Cleaners
may cause respiratory irritation
Only in: Household Cleaners
some
GHS Data from ECHA Website - European Chemicals Agency (ECHA)
Impurity: ETHYLENE OXIDE
Causes serious eye irritation
Only in: Household Cleaners
Causes serious eye irritation
Only in: Household Cleaners
some
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: 1,4-DIOXANE
Causes serious eye irritation
Only in: Household Cleaners
Causes serious eye irritation
Only in: Household Cleaners
some
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: ETHYLENE OXIDE
Causes serious eye damage
Only in: Household Cleaners
Causes serious eye damage
Only in: Household Cleaners
some
GHS Data from ECHA Website - European Chemicals Agency (ECHA)
Impurity: ETHYLENE OXIDE
Causes skin irritation
Only in: Household Cleaners
Causes skin irritation
Only in: Household Cleaners
some
GHS Data from ECHA Website - European Chemicals Agency (ECHA)
Impurity: ETHYLENE OXIDE
causes serious eye irritation
Only in: Household Cleaners
causes serious eye irritation
Only in: Household Cleaners
some
GHS Data from ECHA Website - European Chemicals Agency (ECHA)
Impurity: ETHYLENE OXIDE
This substance is Generally Recognized as Safe (GRAS) as a food additive by the US Food and Drug Administration
Only in: Household Cleaners
This substance is Generally Recognized as Safe (GRAS) as a food additive by the US Food and Drug Administration
Only in: Household Cleaners
low
FDA - Priority based Assessment of Food Additive (PAFA) - U.S. Food and Drug Administration (FDA)
Impurity: 1,4-DIOXANE
EPA testing shows this substance has low acute toxicity to aquatic life
EPA testing shows this substance has low acute toxicity to aquatic life
low
EPA Fathead Minnow Acute Toxicity Database - Environmental Protection Agency (EPA)
