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DIALKYL DIMETHYL AMMONIUM CHLORIDES (DDAC)

Products with this unspecific ingredient may be composed of any the specific substances listed below. The evidence shown is based on the most concerning group member.
Asthma/Respiratory
 
Moderate Concern
 
Skin Allergies &
Irritation
 
No Data, Some Concern
 
Developmental &
Reproductive Toxicity
 
Moderate Concern
 
Cancer
 
No Data, Some Concern
 
Environment
 
Moderate Concern
 
Top scoring factors: May contain ingredients with potential for respiratory effects; general systemic/organ effects; developmental/endocrine/reproductive effects
This unspecific ingredient, Dialkyl dimethyl ammonium chlorides (DDAC), can be found in products.
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Evidence

Health issue
 
Level of Concern
 
Source
Dialkyl dimethyl ammonium chlorides (DDAC)
Asthmagen (allergic)
 
moderate
 
AOEC Asthmagen list - AOEC
Dialkyl dimethyl ammonium chlorides (DDAC)
Asthmagen
 
some
 
AOEC Asthmagen list - AOEC
Dialkyl dimethyl ammonium chlorides (DDAC)
EPA's review of industry submitted toxicity data and the potential for human exposure concludes that this substance poses a moderate risk for human health.
 
some
 
EPA Hazard-Based Prioritizations - Risks - Environmental Protection Agency (EPA)
Dialkyl dimethyl ammonium chlorides (DDAC)
A peer-reviewed publication reports quaternary ammonium compounds cause reproductive toxicity in animals.
 
some
 
Vanessa E. Melin, Travis E. Melin, Brian J. Dessify, Christina T. Nguyen, Caroline S. Shea & Terry C. Hrubec. 2015. Quaternary Ammonium Disinfectants Cause Subfertility in Mice by Targeting both Male and Female Reproductive Processes. Reproductive toxicology (Elmsford, N.Y.).
Dialkyl dimethyl ammonium chlorides (DDAC)
A peer-reviewed publication reports quaternary ammonium compounds cause reproductive toxicity in animals.
 
some
 
Vanessa E. Melin, Haritha Potineni, Patricia Hunt, Jodi Griswold, Bill Siems, Stephen R. Werre & Terry C. Hrubec. 2014. Exposure to common quaternary ammonium disinfectants decreases fertility in mice. Reproductive toxicology (Elmsford, N.Y.) 50, 163-70.
Dialkyl dimethyl ammonium chlorides (DDAC)
A peer-reviewed publication reports quaternary ammonium compounds cause reproductive toxicity in animals.
 
some
 
Vanessa E. Melin, Travis E. Melin, Brian J. Dessify, Christina T. Nguyen, Caroline S. Shea & Terry C. Hrubec. 2015. Quaternary Ammonium Disinfectants Cause Subfertility in Mice by Targeting both Male and Female Reproductive Processes. Reproductive toxicology (Elmsford, N.Y.).
Dialkyl dimethyl ammonium chlorides (DDAC)
A peer-reviewed publication reports quaternary ammonium compounds cause reproductive toxicity in animals.
 
some
 
Vanessa E. Melin, Haritha Potineni, Patricia Hunt, Jodi Griswold, Bill Siems, Stephen R. Werre & Terry C. Hrubec. 2014. Exposure to common quaternary ammonium disinfectants decreases fertility in mice. Reproductive toxicology (Elmsford, N.Y.) 50, 163-70.
 
 
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EWG provides information on cleaning product ingredients from the published scientific... continue reading →
EWG provides information on cleaning product ingredients from published scientific literature, to supplement incomplete data available from companies and the government. The ratings indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors that determine actual health risks, if any. (Hide)
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