Evidence
Health issue
Level of Concern
Source
Hydrotropes
The Cosmetic Ingredient Review Panel concluded this substance is safe for use when formulated to be non-sensitizing.
The Cosmetic Ingredient Review Panel concluded this substance is safe for use when formulated to be non-sensitizing.
some
Cosmetic Ingredient Review (CIR): CIR Assessments
Impurities
Health issue
Level of Concern
Source
Hydrotropes
Impurity: NITROSAMINES
Known to cause cancer
Impurity: NITROSAMINES
Known to cause cancer
some
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
Hydrotropes
Impurity: NITROSAMINES
Probably carcinogenic to humans
Impurity: NITROSAMINES
Probably carcinogenic to humans
some
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Hydrotropes
Impurity: NITROSAMINES
Probably carcinogenic to humans
Impurity: NITROSAMINES
Probably carcinogenic to humans
some
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer
Hydrotropes
Impurity: NITROSAMINES
Reasonably Anticipated To Be Human Carcinogen
Impurity: NITROSAMINES
Reasonably Anticipated To Be Human Carcinogen
some
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
Hydrotropes
Impurity: NITROSAMINES
NTP Toxcast scored 1.5-2.5
Impurity: NITROSAMINES
NTP Toxcast scored 1.5-2.5
some
National Toxicology Program (NTP): EWG Toxcast Analysis