Very toxic to aquatic life
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high
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EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Causes severe skin burns and eye damage
Only in: Oven Cleaner; Drain Opener/Clog Remover; Hard Water Stain Remover; Toilet Cleaner; Stove Top Cleaner; Household Cleaners
|
high
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Asthmagen (sensitizing)
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moderate
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Association of Occupational and Environmental Clinics (AOEC): AOEC Exposure Code List (2020 Update)
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Asthmagen (sensitizing)
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moderate
|
Association of Occupational and Environmental Clinics (AOEC): AOEC Exposure Code List (2020 Update)
|
Harmful in contact with skin
Only in: Household Cleaners
|
moderate
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
Harmful if swallowed
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
A peer-reviewed publication reports some quaternary ammonium compounds cause reproductive toxicity in animals.
|
some
|
Vanessa E. Melin, Travis E. Melin, Brian J. Dessify, Christina T. Nguyen, Caroline S. Shea & Terry C. Hrubec. 2015. Quaternary Ammonium Disinfectants Cause Subfertility in Mice by Targeting both Male and Female Reproductive Processes. Reproductive toxicology (Elmsford, N.Y.).
|
A peer-reviewed publication reports some quaternary ammonium compounds cause reproductive toxicity in animals.
|
some
|
Vanessa E. Melin, Haritha Potineni, Patricia Hunt, Jodi Griswold, Bill Siems, Stephen R. Werre & Terry C. Hrubec. 2014. Exposure to common quaternary ammonium disinfectants decreases fertility in mice. Reproductive toxicology (Elmsford, N.Y.) 50, 163-70.
|
Causes severe skin burns and eye damage
Only in: Drain Opener/Clog Remover; Oven Cleaner; Hard Water Stain Remover; Toilet Cleaner; Stove Top Cleaner; Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
NTP Toxcast scored 2.5-3.5
|
some
|
National Toxicology Program (NTP): EWG Toxcast Analysis
|
Quaternary ammonium compounds detected in human blood was associated with increased inflammation, decreased mitochondrial function and disruption of cholesterol.
|
some
|
Terry C. Hrubec, Ryan P. Seguin, Libin Xu, Gino A. Cortopassi, Sandipan Datta, Alexandra L. Hanlon, Alicia J. Lozano, Valerie A. McDonald, Claire A. Healy, Tyler C. Anderson, Najaha A. Musse & Richard T. Williams. 2021. Altered toxicological endpoints in humans from common quaternary ammonium compound disinfectant exposure. Toxicology reports 8, 646-656.
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This substance impacted cholesterol biosynthesis.
|
some
|
Josi Herron, Rosalyn C. Reese, Keri A. Tallman, Rohini Narayanaswamy, Ned A. Porter & Libin Xu. 2016. Identification of Environmental Quaternary Ammonium Compounds as Direct Inhibitors of Cholesterol Biosynthesis. Toxicological sciences : an official journal of the Society of Toxicology 151(2), 261-70.
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Quaternary ammonium compounds altered neurodevelopment in cells.
|
some
|
Josi M. Herron, Hideaki Tomita, Collin C. White, Terrance J. Kavanagh & Libin Xu. 2021. Benzalkonium Chloride Disinfectants Induce Apoptosis, Inhibit Proliferation, and Activate the Integrated Stress Response in a 3-D in Vitro Model of Neurodevelopment. Chemical research in toxicology 34(5), 1265-1274.
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