among workers at detergent factories, detergent protease exposure is associated with respiratory disease
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some
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A. Brant, S. Upchurch, M. van Tongeren, C. Zekveld, J. Helm, F. Barnes, A. J. Newman Taylor & P. Cullinan. 2009. Detergent protease exposure and respiratory disease: case-referent analysis of a retrospective cohort. Occupational and environmental medicine 66(11), 754-8.
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for workers at detergent factories, detergent enzyme exposure (proteases, alpha-amylase, lipase and cellulase) is associated with respiratory and allergic sensitization
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some
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F. G. B. G. J. van Rooy, R. Houba, N. Palmen, M. Zengeni, I. Sander, J. Spithoven, J. M. Rooyackers & D. J. J. Heederik. 2009. A cross-sectional study among detergent workers exposed to liquid detergent enzymes. Occupational and environmental medicine 66(11), 759-65.
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for workers in detergent factories, detergent enzyme exposure is associated with occupational asthma
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some
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A. Brant, C. Zekveld, J. Welch, M. Jones, A. Newman Taylor & P. Cullinan. 2006. The prognosis of occupational asthma due to detergent enzymes: clinical, immunological and employment outcomes. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 36(4), 483-8.
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for workers at detergent factories, detergent enzyme exposure (proteases, alpha-amylase, lipase and cellulase) is associated with respiratory and allergic sensitization
|
some
|
F. G. B. G. J. van Rooy, R. Houba, N. Palmen, M. Zengeni, I. Sander, J. Spithoven, J. M. Rooyackers & D. J. J. Heederik. 2009. A cross-sectional study among detergent workers exposed to liquid detergent enzymes. Occupational and environmental medicine 66(11), 759-65.
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May cause allergy or asthma symptoms of breathing difficulties if inhaled
Only in: Household Cleaners
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some
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European Chemicals Agency (ECHA): GHS Data from ECHA Website
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for workers at detergent factories, detergent enzyme exposure (proteases, alpha-amylase, lipase and cellulase) is associated with respiratory and allergic sensitization
|
some
|
F. G. B. G. J. van Rooy, R. Houba, N. Palmen, M. Zengeni, I. Sander, J. Spithoven, J. M. Rooyackers & D. J. J. Heederik. 2009. A cross-sectional study among detergent workers exposed to liquid detergent enzymes. Occupational and environmental medicine 66(11), 759-65.
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6-month inhalation exposure to pre-spotter laundry detergent product was not associated with allergic sensitization
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low
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John A. Weeks, Robert A. Harper, Ronald A. Simon & Joel D. Burdick. 2011. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutaneous and ocular toxicology 30(4), 272-9.
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European Union Ecolabel program data shows this substance has moderate acute toxicity to aquatic life
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low
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EU Ecolabel: Detergents Ingredients Database
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Review did not find a link between consumer exposure to detergent enzymes and respiratory sensitization
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low
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Katherine Sarlo, Donald B. Kirchner, Esperanza Troyano, Larry A. Smith, Gregory J. Carr & Carlos Rodriguez. 2010. Assessing the risk of type 1 allergy to enzymes present in laundry and cleaning products: evidence from the clinical data. Toxicology 271(3), 87-93.
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A review article reports this substance is non-genotoxic
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low
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David Basketter, Ninna Berg, Cees Broekhuizen, Mark Fieldsend, Sheila Kirkwood, Cornelia Kluin, Sophie Mathieu & Carlos Rodriguez. 2012. Enzymes in cleaning products: An overview of toxicological properties and risk assessment/management. Regulatory toxicology and pharmacology : RTP.
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The European Union Ecolabel program reports this substance is readily biodegradable.
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low
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EU Ecolabel: Detergents Ingredients Database
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The European Union Ecolabel program reports this substance is anaerobically degradable.
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low
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EU Ecolabel: Detergents Ingredients Database
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