Enzymes
among workers at detergent factories, detergent protease exposure is associated with respiratory disease

some

A. Brant, S. Upchurch, M. van Tongeren, C. Zekveld, J. Helm, F. Barnes, A. J. Newman Taylor & P. Cullinan. 2009. Detergent protease exposure and respiratory disease: case-referent analysis of a retrospective cohort. Occupational and environmental medicine 66(11), 754-8.

Enzymes
for workers at detergent factories, detergent enzyme exposure (proteases, alpha-amylase, lipase and cellulase) is associated with respiratory and allergic sensitization

some

F. G. B. G. J. van Rooy, R. Houba, N. Palmen, M. Zengeni, I. Sander, J. Spithoven, J. M. Rooyackers & D. J. J. Heederik. 2009. A cross-sectional study among detergent workers exposed to liquid detergent enzymes. Occupational and environmental medicine 66(11), 759-65.

Enzymes
for workers in detergent factories, detergent enzyme exposure is associated with occupational asthma

some

A. Brant, C. Zekveld, J. Welch, M. Jones, A. Newman Taylor & P. Cullinan. 2006. The prognosis of occupational asthma due to detergent enzymes: clinical, immunological and employment outcomes. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 36(4), 483-8.

Enzymes
for workers at detergent factories, detergent enzyme exposure (proteases, alpha-amylase, lipase and cellulase) is associated with respiratory and allergic sensitization

some

F. G. B. G. J. van Rooy, R. Houba, N. Palmen, M. Zengeni, I. Sander, J. Spithoven, J. M. Rooyackers & D. J. J. Heederik. 2009. A cross-sectional study among detergent workers exposed to liquid detergent enzymes. Occupational and environmental medicine 66(11), 759-65.

Enzymes
for workers at detergent factories, detergent enzyme exposure (proteases, alpha-amylase, lipase and cellulase) is associated with respiratory and allergic sensitization

some

F. G. B. G. J. van Rooy, R. Houba, N. Palmen, M. Zengeni, I. Sander, J. Spithoven, J. M. Rooyackers & D. J. J. Heederik. 2009. A cross-sectional study among detergent workers exposed to liquid detergent enzymes. Occupational and environmental medicine 66(11), 759-65.

Enzymes
6-month inhalation exposure to pre-spotter laundry detergent product was not associated with allergic sensitization

low

John A. Weeks, Robert A. Harper, Ronald A. Simon & Joel D. Burdick. 2011. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutaneous and ocular toxicology 30(4), 272-9.

Enzymes
European Union Ecolabel program data shows this substance has moderate acute toxicity to aquatic life

low

EU Ecolabel: Detergents Ingredients Database

Enzymes
Review did not find a link between consumer exposure to detergent enzymes and respiratory sensitization

low

Katherine Sarlo, Donald B. Kirchner, Esperanza Troyano, Larry A. Smith, Gregory J. Carr & Carlos Rodriguez. 2010. Assessing the risk of type 1 allergy to enzymes present in laundry and cleaning products: evidence from the clinical data. Toxicology 271(3), 87-93.

Enzymes
A review article reports this substance is non-genotoxic

low

David Basketter, Ninna Berg, Cees Broekhuizen, Mark Fieldsend, Sheila Kirkwood, Cornelia Kluin, Sophie Mathieu & Carlos Rodriguez. 2012. Enzymes in cleaning products: An overview of toxicological properties and risk assessment/management. Regulatory toxicology and pharmacology : RTP.

Enzymes
The European Union Ecolabel program reports this substance is readily biodegradable.

low

EU Ecolabel: Detergents Ingredients Database

Enzymes
The European Union Ecolabel program reports this substance is anaerobically degradable.

low

EU Ecolabel: Detergents Ingredients Database