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EPIMEDIUM KOREANUM EXTRACT
See how this product scores for common concerns.
No information available on this substance.
| Health Issue | Level of Concern | Source |
|---|
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A peer-reviewed study found E. koreanum extract can disrupt estrogen signaling in rats and in vitro. |
some |
Hyun Ku Kang, Yun-Ho Choi, Hyosuk Kwon, Sang-Bum Lee, Dong-Hyun Kim, Chung Ki Sung, Young In Park & Mi-Sook Dong. 2012. Estrogenic/antiestrogenic activities of a Epimedium koreanum extract and its major components: in vitro and in vivo studies. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 50(8), 2751-9. |
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E. koreanum may disrupt liver enzyme function, according to in vitro test with human cells. |
some |
Qingxiang Zhong, Ziqi Shi, Li Zhang, Rongling Zhong, Zhi Xia, Jing Wang, Hao Wu, Yutong Jiang, E. Sun, Yingjie Wei, Liang Feng, Zhenhai Zhang, Dan Liu, Jie Song & Xiaobin Jia. 2017. The potential of Epimedium koreanum Nakai for herb-drug interaction. The Journal of pharmacy and pharmacology 69(10), 1398-1408. |
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E. koreanum extracts exhibit antioxidant properties in vitro. |
low |
Wenjing Zhang, Haixia Chen, Zhaoshuai Wang, Gaoshuang Lan & Likang Zhang. 2013. Comparative studies on antioxidant activities of extracts and fractions from the leaves and stem of Epimedium koreanum Nakai. Journal of food science and technology 50(6), 1122-9. |
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E. koreanum extracts exhibit antioxidant properties in a mouse study. |
low |
Ji Yun Jung, Sang Mi Park, Hae Li Ko, Jong Rok Lee, Chung A. Park, Sung Hui Byun, Sae Kwang Ku, Il Je Cho & Sang Chan Kim. 2018. Epimedium koreanum Ameliorates Oxidative Stress-Mediated Liver Injury by Activating Nuclear Factor Erythroid 2-Related Factor 2. The American journal of Chinese medicine 46(2), 469-488. |
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A peer-reviewed study reports E. koreanum was not genotoxic in animal or in vitro tests. |
low |
Youn-Hwan Hwang, Hey Jin Yang, Nam-Hui Yim & Jin Yeul Ma. 2017. Genetic toxicity of Epimedium koreanum Nakai. Journal of ethnopharmacology 198, 87-90. |
EWG provides information on cleaning product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any.
HOW WE DETERMINE SCORESThe Healthy Cleaning ingredient hazard score, from A to F, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.
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