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Acid Yellow 23 (Uncertified FD&C Yellow No. 5)

Score:

Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (high), Neurotoxicity (moderate), Endocrine disruption (low), Persistence and bioaccumulation (moderate), Non-reproductive organ system toxicity (moderate), and Contamination concerns (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW_MODERATE

Products with this Ingredient

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styling gel/lotion1 products

Contamination concerns

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Use restrictions

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Concern Reference
Violation of government restrictions - Banned or found unsafe for use in cosmeticsCTFA International Cosmetic Ingredient Dictionary and Handbook
Violation of government restrictions - Banned or found unsafe for use in cosmeticsOpen scientific literature

Persistence and bioaccumulation

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Concern Reference
Persistent or bioaccumulative and moderate to high toxicity concern in humansOpen scientific literature
Not suspected to be bioaccumulativeOpen scientific literature

Neurotoxicity

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Concern Reference
One or more human case studies show significant any effectsOpen scientific literature
One or more human case studies show possible any effectsOpen scientific literature
One or more animal studies show any effects at moderate dosesOpen scientific literature
One or more animal studies show any effects at high dosesOpen scientific literature

Allergies/immunotoxicity

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Concern Reference
Human any toxicant or allergen - moderate evidenceOpen scientific literature
One or more human case studies show possible any or allergenic effectsOpen scientific literature
One or more human case studies show equivocal any or allergenic effectsOpen scientific literature

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as medium human health priorityOpen scientific literature
One or more animal studies show any effects at high doses (low dose studies may be unavailable for this ingredient)Open scientific literature
Classified as not expected to be potentially toxic or harmfulOpen scientific literature

Cancer

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Concern Reference
Cancer - limited evidenceOpen scientific literature
One or more in vitro tests on mammalian cells show positive mutation resultsOpen scientific literature
One or more in vitro tests on cells show inconclusive, but potentially positive mutation resultsOpen scientific literature
Not likely to be mutagenic in humansOpen scientific literature
Not likely to be carcinogenic in humansOpen scientific literature

Endocrine disruption

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Concern Reference
One or more studies show weak endocrine disruptionOpen scientific literature
Associated with endocrine disruptionOpen scientific literature

Developmental/reproductive toxicity

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Concern Reference
One or more animal studies show any effects at high dosesOpen scientific literature
any - weight of evidence unknown/unassessed/unreviewedOpen scientific literature

Data gaps

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Concern Reference
Not assessed for safety in cosmetics by industry panel

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinOpen scientific literature

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodOpen scientific literature

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyOpen scientific literature

Data Sources

  • CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
  • Open scientific/peer reviewed literature

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