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HYDROXYACETOPHENONE
Score:
Data: Limited
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Non-reproductive organ system toxicity (low) and Irritation (skin, eyes, or lungs) (low)
Cancer 
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
| mask | 103 products |
| concealer | 78 products |
| foundation | 60 products |
| facial moisturizer/treatment | 47 products |
| serums & essences | 39 products |
| recreational sunscreen | 25 products |
| daily use with SPF | 22 products |
| moisturizer | 19 products |
| facial cleanser | 18 products |
| around-eye cream | 14 products |
| CC cream | 14 products |
| exfoliant/scrub | 13 products |
| bronzer/highlighter | 11 products |
| body firming lotion | 10 products |
| makeup primer | 9 products |
| lipstick | 8 products |
| toners/astringents | 7 products |
| shampoo | 6 products |
| baby sunscreen | 6 products |
| baby lotion | 4 products |
| hand cream | 4 products |
| shaving cream | 4 products |
| eye shadow | 4 products |
| lip plumper | 4 products |
| body wash/cleanser | 4 products |
| baby soap | 3 products |
| after sun product | 3 products |
| mouthwash | 3 products |
| baby wipes | 2 products |
| hair styling aide | 2 products |
| baby shampoo | 2 products |
| hair treatment/serum | 2 products |
| setting powder/spray | 2 products |
| eye makeup remover | 1 products |
| mascara | 1 products |
| depilatory | 1 products |
| shaving cream (men's) | 1 products |
| hand sanitizer | 1 products |
| brow liner | 1 products |
| bubble bath | 1 products |
| baby bubble bath | 1 products |
| 1 products | |
| makeup remover | 1 products |
| body oil | 1 products |
| conditioner | 1 products |
Irritation (skin, eyes, or lungs)
| Concern | Reference |
|---|---|
| REACH registration: causes serious eye irritation. | European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: chemical_names: HYDROXYACETOPHENONE; cas_numbers: 99-93-4 |
| CLP notification: causes skin irritation. | European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: chemical_names: HYDROXYACETOPHENONE; cas_numbers: 99-93-4 |
Allergies/immunotoxicity
| Concern | Reference |
|---|---|
| Contact dermatitis reported in a human case report. | Tatiana Sanz-Sánchez, Ricardo Valverde Garrido, Paola Maldonado Cid & Rosa M Díaz-Díaz. 2018. Allergic contact dermatitis caused by hydroxyacetophenone in a face cream. Contact dermatitis 78(2), 174-175. |
Organ system toxicity (non-reproductive)
| Concern | Reference |
|---|---|
| CLP notification: harmful if swallowed. | European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: chemical_names: HYDROXYACETOPHENONE; cas_numbers: 99-93-4 |
Ecotoxicology
| Concern | Reference |
|---|---|
| REACH registration: harmful to aquatic life with long lasting effects. | European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: chemical_names: HYDROXYACETOPHENONE; cas_numbers: 99-93-4 |
Data Sources
- European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: chemical_names: HYDROXYACETOPHENONE; cas_numbers: 99-93-4
- Tatiana Sanz-Sánchez, Ricardo Valverde Garrido, Paola Maldonado Cid & Rosa M Díaz-Díaz. 2018. Allergic contact dermatitis caused by hydroxyacetophenone in a face cream. Contact dermatitis 78(2), 174-175.
ABOUT THE SKIN DEEP® RATINGS
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
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