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ALLYL HEPTANOATE

Score:

Data: Limited

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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recreational sunscreen10 products
shampoo2 products
after sun product1 products
mask1 products
baby shampoo1 products
baby soap1 products
body wash/cleanser1 products
hand cream1 products
fragrance for men1 products
fragrance for women1 products
conditioner1 products
hand sanitizer1 products
baby lotion1 products

Use restrictions

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Concern Reference
Restricted in European cosmeticsEU Cosmetics Directive 2015. CosIng. Appears as: listid: COSING-41339; Chemical_Name: ALLYL HEPTANOATE; ; CAS: 142-19-8
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - anyCosIng

Organ system toxicity (non-reproductive)

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Concern Reference
Allyl esters are linked to hepatotoxicity.Takashi Yamada, Ovanes Mekenyan, Yasushi Yamazoe, Akihiko Hirose, Atsushi Ono, Eiichi Kamata, Jun Yamada, Yuki Sakuratani, Ryuichi Hasegawa, Yushiro Tanaka & Makoto Hayashi 2013. A category approach to predicting the repeated-dose hepatotoxicity of allyl esters. Regulatory toxicology and pharmacology : RTP 65(2), 189-95.
Classified as toxic if swallowed, toxic in contact with skin, and toxic if inhaled.European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Allyl heptanoate; prop-2-en-1-yl heptanoate; -; 2-Propenyl heptanoate; Allyl Heptanoate; Allylheptanoat; HEPTANOATE 2-PROPENYL; Heptanoic acid, 2-propen-1-yl ester; Heptanoic acid, 2-propenyl ester; prop-2-en-1-yl heptanoate; Prop-2-enyl heptanoate; A; cas_numbers: 142-19-8
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Irritation (skin, eyes, or lungs)

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Concern Reference
Classified as causes serious eye irritation.European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Allyl heptanoate; prop-2-en-1-yl heptanoate; -; 2-Propenyl heptanoate; Allyl Heptanoate; Allylheptanoat; HEPTANOATE 2-PROPENYL; Heptanoic acid, 2-propen-1-yl ester; Heptanoic acid, 2-propenyl ester; prop-2-en-1-yl heptanoate; Prop-2-enyl heptanoate; A; cas_numbers: 142-19-8

Endocrine disruption

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Concern Reference
Evidence of estrogen disruption in cellular assays.National Toxicology Program (NTP) 2020. EWG Toxcast Analysis. Appears as: CAS: 142-19-8; Chemical_Name: ALLYL HEPTANOATE

Ecotoxicology

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Concern Reference
Suspected to be an environmental toxinEnvironment Canada Domestic Substance List
Classified as very toxic to aquatic life and harmful to aquatic life with long lasting effects.European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Allyl heptanoate; prop-2-en-1-yl heptanoate; -; 2-Propenyl heptanoate; Allyl Heptanoate; Allylheptanoat; HEPTANOATE 2-PROPENYL; Heptanoic acid, 2-propen-1-yl ester; Heptanoic acid, 2-propenyl ester; prop-2-en-1-yl heptanoate; Prop-2-enyl heptanoate; A; cas_numbers: 142-19-8

Data gaps

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Concern Reference
0 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Persistence and bioaccumulation

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Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • EU Cosmetics Directive 2015. CosIng. Appears as: listid: COSING-41339; Chemical_Name: ALLYL HEPTANOATE; ; CAS: 142-19-8
  • European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
  • Takashi Yamada, Ovanes Mekenyan, Yasushi Yamazoe, Akihiko Hirose, Atsushi Ono, Eiichi Kamata, Jun Yamada, Yuki Sakuratani, Ryuichi Hasegawa, Yushiro Tanaka & Makoto Hayashi 2013. A category approach to predicting the repeated-dose hepatotoxicity of allyl esters. Regulatory toxicology and pharmacology : RTP 65(2), 189-95.
  • European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Allyl heptanoate; prop-2-en-1-yl heptanoate; -; 2-Propenyl heptanoate; Allyl Heptanoate; Allylheptanoat; HEPTANOATE 2-PROPENYL; Heptanoic acid, 2-propen-1-yl ester; Heptanoic acid, 2-propenyl ester; prop-2-en-1-yl heptanoate; Prop-2-enyl heptanoate; A; cas_numbers: 142-19-8
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • National Toxicology Program (NTP) 2020. EWG Toxcast Analysis. Appears as: CAS: 142-19-8; Chemical_Name: ALLYL HEPTANOATE
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

About this Ingredient's Score Range

  • Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data.

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