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PESTICIDES
Score:
Data: Fair
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Use restrictions (high) and Neurotoxicity (moderate)
Cancer 
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
Cancer
| Concern | Reference |
|---|---|
| Iprodione, procymidone, vinclozolin are known to cause cancer. | Proposition 65 List of Carcinogens (2013) can be obtained from http://wwwoehha.ca.gov/prop65/prop65_list/Newlist.html. |
| Early life exposure leads to greater risk of chronic effects such as cancer. | NAS (National Academy of Sciences) 1993. Pesticides in the Diets of Infants and Children. National Academy of Sciences, Commission of Life Science. Washington, DC. http://www.nap.edu/catalog.php?record_id=2126 |
Use restrictions
| Concern | Reference |
|---|---|
| Many pesticides are not allowed to be used in cosmetics. | Federal Food, Drug, and Cosmetic Act (FD&C Act), FIFRA & Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) |
| Numerous ingredients have recommendations to minimize pesticide contamination. | CIR (Cosmetic Ingredient Review) 2007. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC. |
Allergies/immunotoxicity
| Concern | Reference |
|---|---|
| Early life exposure leads to greater risk of chronic effects such as immune dysfunction. | NAS (National Academy of Sciences) 1993. Pesticides in the Diets of Infants and Children. National Academy of Sciences, Commission of Life Science. Washington, DC. http://www.nap.edu/catalog.php?record_id=2126 |
Neurotoxicity
| Concern | Reference |
|---|---|
| Early life exposure leads to greater risk of chronic effects such as neurodevelopmental impairment. | NAS (National Academy of Sciences) 1993. Pesticides in the Diets of Infants and Children. National Academy of Sciences, Commission of Life Science. Washington, DC. http://www.nap.edu/catalog.php?record_id=2126 |
| IQ and Neurodevelopment effects | Rauh V, Arunajadai S, Horton M, Perera F, Hoepner L, Barr DB, et al 2011. 7-Year Neurodevelopmental Scores and Prenatal Exposure to Chlorpyrifos, a Common Agricultural Pesticide. Environ Health Perspect doi: 10.1289/ehp.1003160. |
Developmental/reproductive toxicity
| Concern | Reference |
|---|---|
| Iprodione delayed puberty and lowered serum testosterone. | Blystone, Chad R, et al. "Iprodione delays male rat pubertal development, reduces serum testosterone levels, and decreases ex vivo testicular testosterone production." Toxicology letters 174.1 (2007): 74-81. |
Data gaps
| Concern | Reference |
|---|---|
| 25628 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Data Sources
- Proposition 65 List of Carcinogens (2013) can be obtained from http://wwwoehha.ca.gov/prop65/prop65_list/Newlist.html.
- NAS (National Academy of Sciences) 1993. Pesticides in the Diets of Infants and Children. National Academy of Sciences, Commission of Life Science. Washington, DC. http://www.nap.edu/catalog.php?record_id=2126
- Federal Food, Drug, and Cosmetic Act (FD&C Act), FIFRA & Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA)
- CIR (Cosmetic Ingredient Review) 2007. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
- Rauh V, Arunajadai S, Horton M, Perera F, Hoepner L, Barr DB, et al 2011. 7-Year Neurodevelopmental Scores and Prenatal Exposure to Chlorpyrifos, a Common Agricultural Pesticide. Environ Health Perspect doi: 10.1289/ehp.1003160.
- Blystone, Chad R, et al. "Iprodione delays male rat pubertal development, reduces serum testosterone levels, and decreases ex vivo testicular testosterone production." Toxicology letters 174.1 (2007): 74-81.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
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