Other ConcernsNeurotoxicity (high), Non-reproductive organ system toxicity (high), Irritation (skin, eyes, or lungs) (high), and Occupational hazards (high)
Unacceptable: EWG VERIFIED products cannot contain this ingredient
Xylene is a mixture of isomers of the aromatic compound.
See how this product scores for common concerns.
MODERATEAllergies & Immunotoxicity
MODERATEDevelopmental and Reproductive Toxicity
- DATA SOURCES
Products with this Ingredient
|Known human nervous system toxicant||Open scientific literature|
|nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study||National Library of Medicine HazMap|
Organ system toxicity (non-reproductive)
|Known human respiratory toxicant||EPA Hazardous Air Pollutants|
|Classified as toxic or harmful||CPS&Q - Classification & Labelling|
|Limited evidence of gastrointestinal or liver toxicity||National Library of Medicine HazMap|
|Limited evidence of gastrointestinal or liver toxicity||Scorecard.org Toxicity Information|
|One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)||EPA Toxic Release Inventory PBTs|
|One or more animal studies show any effects at moderate doses (low dose studies may be unavailable for this ingredient)||EPA Categorized List of Inert Pesticide Ingredients|
|Classified as a low human health priority||Environment Canada Domestic Substance List|
|Classified as not expected to be potentially toxic or harmful||Environment Canada Domestic Substance List|
|reproductive - weight of evidence unknown/unassessed/unreview: published lit review or major tox study||National Library of Medicine HazMap|
Irritation (skin, eyes, or lungs)
|Classified as irritant||CPS&Q - Classification & Labelling|
|Allowed workplace exposures restricted to low doses||CPS&Q - Classification & Labelling|
|Limited evidence of reproductive toxicity||National Library of Medicine HazMap|
|Limited evidence of developmental toxicity||Scorecard.org Toxicity Information|
|Limited evidence of immune system toxicity or allergies||Scorecard.org Toxicity Information|
|Occupational hazards related to handling||CPS&Q - Classification & Labelling|
Persistence and bioaccumulation
|Not suspected to be bioaccumulative||Environment Canada Domestic Substance List|
|Not suspected to be persistent||Environment Canada Domestic Substance List|
|Not suspected to be an environmental toxin||Environment Canada Domestic Substance List|
|Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gaps||Int'l Agency for Research on Cancer (IARC) - Carcinogens|
|5886 studies in PubMed science library may include information on the toxicity of this chemical||NLM PubMed|
- Open scientific/peer reviewed literature
- NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
- EPA (U.S. Environmental Protection Agency). 2005. Office of Air. The 112(b)1 Hazardous Air Pollutants List (as modified). Last modified: 12 Dec 2005.
- CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
- ED (Environmental Defense). 2006. Scorecard _ The Pollution Information Site. http://www.scorecard.org.
- EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
- EPA (U.S. Environmental Protection Agency). 1987 & 2005. Office of Pesticide Programs. Inert (other) Pesticide Ingredients in Pesticide Products - Categorized List of Inert (other) Pesticide Ingredients.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.
Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.HOW WE DETERMINE SCORES
The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.
The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.