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PROPANEDIOL
Score:
Data: Fair
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Enhanced skin absorption, Endocrine disruption (low), and Irritation (skin, eyes, or lungs) (high)
Cancer 
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
| facial moisturizer/treatment | 203 products |
| serums & essences | 177 products |
| mask | 156 products |
| foundation | 148 products |
| concealer | 123 products |
| moisturizer with SPF | 75 products |
| facial cleanser | 65 products |
| beach & sport sunscreen | 64 products |
| moisturizer | 62 products |
| antiperspirant/deodorant | 50 products |
| eye shadow | 42 products |
| exfoliant/scrub | 37 products |
| body wash/cleanser | 37 products |
| toners/astringents | 37 products |
| around-eye cream | 36 products |
| makeup primer | 35 products |
| liquid hand soap | 33 products |
| shampoo | 32 products |
| eye liner | 31 products |
| conditioner | 29 products |
| hair treatment/serum | 22 products |
| makeup remover | 19 products |
| hair styling aide | 18 products |
| mascara | 17 products |
| styling gel/lotion | 16 products |
| hair color and bleaching | 15 products |
| anti-aging | 12 products |
| CC cream | 10 products |
| sunless tanning | 9 products |
| bronzer/highlighter | 9 products |
| hand sanitizer | 9 products |
| baby sunscreen | 9 products |
| lipstick | 9 products |
| 8 products | |
| antiperspirant/deodorant (men's) | 7 products |
| BB cream | 7 products |
| brow liner | 7 products |
| shaving cream | 6 products |
| detangler | 6 products |
| shaving cream (men's) | 6 products |
| body firming lotion | 6 products |
| baby lotion | 6 products |
| after sun product | 5 products |
| blush | 5 products |
| hand cream | 4 products |
| after shave | 4 products |
| baby shampoo | 4 products |
| oil controller | 4 products |
| foot moisturizer | 4 products |
| baby soap | 3 products |
| mouthwash | 3 products |
| hair spray | 3 products |
| fragrance for women | 3 products |
| makeup with SPF | 2 products |
| beard care | 2 products |
| bubble bath | 2 products |
| toothpaste | 2 products |
| eye makeup remover | 1 products |
| damaged skin treatment | 1 products |
| lip plumper | 1 products |
| body spray | 1 products |
| beard oil | 1 products |
| beard cleanser | 1 products |
| muscle/joint soreness | 1 products |
| styling mousse/foam | 1 products |
| facial powder | 1 products |
| baby bubble bath | 1 products |
| lip balm | 1 products |
| baby toothpaste | 1 products |
| lip balm with SPF | 1 products |
Enhanced skin absorption
| Concern | Reference |
|---|---|
| Penetration enhancer - alters skin structure, allows other chemicals to penetrate deeper into the skin | Cosmetic Ingredient Review (CIR) 2020. CIR Assessments. Appears as: ; Chemical_Name: Propanediol; ; ; Classification: QQQ01; PE; M+; |
Irritation (skin, eyes, or lungs)
| Concern | Reference |
|---|---|
| Classified as skin irritant | National Library of Medicine HazMap |
| Mild skin irritation observed in animal tests. | Cosmetic Ingredient Review (CIR) 2020. CIR Assessments. Appears as: ; Chemical_Name: Propanediol; ; ; Classification: QQQ01; PE; M+; |
| Causes skin irritation. | European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Propane-1,3-diol; propane-1,3-diol; -; 1,3-Dihydroxypropane; 1,3-Propanediol; 1,3-Propylene glycol; Propan-1,3-diol; Propane-1,3-diol; Propane-1,3-diol; Susterra; Zemea; cas_numbers: 504-63-2 |
Cancer
| Concern | Reference |
|---|---|
| Genotoxicity observed in mammalian cell assay. | Cosmetic Ingredient Review (CIR) 2020. CIR Assessments. Appears as: ; Chemical_Name: Propanediol; ; ; Classification: QQQ01; PE; M+; |
Endocrine disruption
| Concern | Reference |
|---|---|
| Evidence of endocrine disruption in in vitro assays. | National Toxicology Program (NTP) 2020. EWG Toxcast Analysis. Appears as: CAS: 504-63-2; Chemical_Name: Propanediol |
Data gaps
| Concern | Reference |
|---|---|
| 81588 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Ecotoxicology
| Concern | Reference |
|---|---|
| Not suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Organ system toxicity (non-reproductive)
| Concern | Reference |
|---|---|
| Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List |
Persistence and bioaccumulation
| Concern | Reference |
|---|---|
| Not suspected to be persistent | Environment Canada Domestic Substance List |
| Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
Data Sources
- Cosmetic Ingredient Review (CIR) 2020. CIR Assessments. Appears as: ; Chemical_Name: Propanediol; ; ; Classification: QQQ01; PE; M+;
- NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
- European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Propane-1,3-diol; propane-1,3-diol; -; 1,3-Dihydroxypropane; 1,3-Propanediol; 1,3-Propylene glycol; Propan-1,3-diol; Propane-1,3-diol; Propane-1,3-diol; Susterra; Zemea; cas_numbers: 504-63-2
- National Toxicology Program (NTP) 2020. EWG Toxcast Analysis. Appears as: CAS: 504-63-2; Chemical_Name: Propanediol
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
ABOUT THE SKIN DEEP® RATINGS
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
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Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer
