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Data: Robust

Methyl Eugenol

IMAGE SOURCE: PubChem

SEARCH PRODUCTS

Other Concerns

Use restrictions (high) and Non-reproductive organ system toxicity (moderate)

SYNONYMS

1,2-DIMETHOXY-4-(2-PROPENYL)- BENZENE, 1,2-DIMETHOXY-4-(2-PROPENYL)BENZENE, 3,4-DIMETHOXYALLYLBENZENE, 4-ALLYLVERATROLE, ALLYLVERATROLE, BENZENE, 1,2-DIMETHOXY-4-(2-PROPENYL)-, BENZENE, 1,2DIMETHOXY4(2PROPENYL), EUGENOL METHYL ETHER, EUGENYL METHYL ETHER, METHYL EUGENOL, and VERATROLE METHYL ETHER

Methyl Eugenol is an aromatic compound.

Common concerns

See how this product scores for common concerns.

  • MODERATE
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reingredientive Toxicity
  • HIGH
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

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hair spray2 products
facial moisturizer/treatment1 products

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Classified as a high human health priorityEnvironment Canada Domestic Substance List
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Cancer

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CONCERN REFERENCE
Possible human carcinogenCalifornia EPA Proposition 65
Possible human carcinogenNTP Report on Carcinogens, 11th Edition
Possible human carcinogenNTP - Tumor Induction in Mammary Gland
Limited evidence of carcinogenicityInt'l Agency for Research on Cancer (IARC) - Carcinogens
One or more human case studies show possible cancer findingsNTP - Tumor Induction in Mammary Gland
Cancer - limited evidenceSilent Spring's Mammary Carcinogens Reviews Database

Use restrictions

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CONCERN REFERENCE
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn)International Fragrance Association Codes & Standards
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - anyCosIng
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmeticsCanada - Prohibited and Restricted Cosmetics Ingredients

Ecotoxicology

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CONCERN REFERENCE
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

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CONCERN REFERENCE
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Data gaps

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CONCERN REFERENCE
257 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • California EPA (California Environmental Protection Agency). 9/2008. Office of Environmental Health Hazard Assessment. Safe Drinking Water and Toxic Enforcement Act of 1986. Chemicals known to the State to cause cancer or reproductive toxicity.
  • NTP (National Toxicology Program). 2005. Report on Carcinogens, Eleventh Edition; U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program.
  • NTP (National Toxicology Program) 2006. Chemicals Associated with Site-Specific Tumor Induction in Mammary Gland.
  • IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
  • Rudel RA, KR Attfield, JN Schifano and JG Brody. Chemicals Causing Mammary Gland Tumors in Animals Signal New Directions for Epidemiology, Chemicals Testing, and Risk Assessment for Breast Cancer Prevention. CANCER Supplement. 2007 Jun 15;109(12):2635-2666.
  • IFRA (International Fragrance Association). 2006. Codes and Standards.
  • European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
  • Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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