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Data: Fair

Isoleucine

IMAGE SOURCE: PubChem

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Other Concerns


SYNONYMS

2-AMINO-3-METHYLPENTANOIC ACID, 2-AMINO-3-METHYLVALERIC ACID, 3-METHYL- ERYTHRO- L-NORVALINE, D,L-ISOLEUCINE, ERYTHRO- L-NORVALINE, 3-METHYL-, ISOLEUCINE, L-ISOLEUCINE, and L-NORVALINE, 3-METHYL-, ERYTHRO-

Restricted

Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation


Isoleucine is an amino acid.

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • LOW
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

Expand content Collapse content
foundation88 products
conditioner25 products
shampoo24 products
mask16 products
hair treatment/serum12 products
around-eye cream11 products
facial moisturizer/treatment10 products
hair styling aide9 products
facial cleanser9 products
body wash/cleanser9 products
serums & essences8 products
liquid hand soap5 products
toners/astringents5 products
exfoliant/scrub3 products
styling gel/lotion2 products
moisturizer2 products
makeup remover2 products
antiperspirant/deodorant (men's)1 products
foot cleansing1 products
hand cream1 products
other eye makeup1 products
makeup primer1 products
hair-loss treatment1 products
recreational sunscreen1 products
styling mousse/foam1 products
bar soap1 products
shaving cream1 products
detangler1 products
damaged skin treatment1 products
anti-aging1 products
hair spray1 products

Multiple, additive exposure sources

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CONCERN REFERENCE
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food
Designated as safe for general or specific, limited use in foodFDA Food Additive Status

Informational

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CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyOpen scientific literature

Ecotoxicology

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CONCERN REFERENCE
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data gaps

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CONCERN REFERENCE
12092 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • Open scientific/peer reviewed literature
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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