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DIETHANOLAMINE

Score:

Data: Robust

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (high), Non-reproductive organ system toxicity (high), Irritation (skin, eyes, or lungs) (high), Occupational hazards (high), and Contamination concerns (high)

Cancer

Cancer concern is MODERATE

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

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serums & essences1 products
facial moisturizer/treatment1 products

Contamination concerns

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Chemical
NITROSAMINES

Irritation (skin, eyes, or lungs)

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Concern Reference
Classified as irritantCPS&Q - Classification & Labelling
Limited evidence of skin irritationNational Library of Medicine HazMap

Use restrictions

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Concern Reference
Violation of government restrictions - Banned or found unsafe for use in cosmeticsCanada - Prohibited and Restricted Cosmetics Ingredients
Violation of government restrictions - Banned or found unsafe for use in cosmeticsCosIng
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

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Concern Reference
Known human respiratory toxicantEPA Hazardous Air Pollutants
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Classified as toxic or harmfulCPS&Q - Classification & Labelling
Limited evidence of cardiovascular or blood toxicityScorecard.org Toxicity Information
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)EPA Toxic Release Inventory PBTs
One or more animal studies show any effects at moderate doses (low dose studies may be unavailable for this ingredient)EPA Categorized List of Inert Pesticide Ingredients

Occupational hazards

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Concern Reference
Allowed workplace exposures restricted to low dosesCPS&Q - Classification & Labelling

Allergies/immunotoxicity

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Concern Reference
Human immune and respiratory toxicant or allergen - strong evidenceAssociation of Occupational and Environmental Clinics
Human skin toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments
Limited evidence of immune system toxicity or allergiesNational Library of Medicine HazMap

Cancer

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Concern Reference
Possible human carcinogenOpen scientific literature
Possible human carcinogenCalifornia EPA Proposition 65
Limited evidence of carcinogenicityOpen scientific literature
Limited evidence of carcinogenicityInt'l Agency for Research on Cancer (IARC) - Carcinogens
Cancer - limited evidenceScorecard.org Toxicity Information
Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gapsInt'l Agency for Research on Cancer (IARC) - Carcinogens

Developmental/reproductive toxicity

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Concern Reference
One or more animal studies show neurodevelopmental effects at moderate dosesOpen scientific literature

Data gaps

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Concern Reference
2147 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Data Sources

  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
  • NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
  • Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
  • European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • EPA (U.S. Environmental Protection Agency). 2005. Office of Air. The 112(b)1 Hazardous Air Pollutants List (as modified). Last modified: 12 Dec 2005.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • ED (Environmental Defense). 2006. Scorecard _ The Pollution Information Site. http://www.scorecard.org.
  • EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
  • EPA (U.S. Environmental Protection Agency). 1987 & 2005. Office of Pesticide Programs. Inert (other) Pesticide Ingredients in Pesticide Products - Categorized List of Inert (other) Pesticide Ingredients.
  • AOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
  • Open scientific/peer reviewed literature
  • California EPA (California Environmental Protection Agency). 9/2008. Office of Environmental Health Hazard Assessment. Safe Drinking Water and Toxic Enforcement Act of 1986. Chemicals known to the State to cause cancer or reproductive toxicity.
  • IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

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