Other ConcernsUse restrictions (high), Non-reproductive organ system toxicity (high), Irritation (skin, eyes, or lungs) (high), Occupational hazards (high), and Contamination concerns (high)
SYNONYMS2,2'-DIHYDROXYDIETHYLAMINE, 2,2'-IMINOBISETHANOL, 2,2'-IMINODIETHANOL, DEA (EWG), DIETHANOLAMINE, ETHANOL, 2,2 IMINOBIS, and N,N-DIETHANOLAMINE
Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation
Diethanolamine is an aliphatic amine.
See how this product scores for common concerns.
MODERATEAllergies & Immunotoxicity
LOWDevelopmental and Reproductive Toxicity
- DATA SOURCES
Products with this Ingredient
|facial moisturizer/treatment||1 products|
Irritation (skin, eyes, or lungs)
|Classified as irritant||CPS&Q - Classification & Labelling|
|Limited evidence of skin irritation||National Library of Medicine HazMap|
|Violation of government restrictions - Banned or found unsafe for use in cosmetics||Canada - Prohibited and Restricted Cosmetics Ingredients|
|Violation of government restrictions - Banned or found unsafe for use in cosmetics||CosIng|
|Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications||Cosmetic Ingredient Review Assessments|
Organ system toxicity (non-reproductive)
|Known human respiratory toxicant||EPA Hazardous Air Pollutants|
|Classified as expected to be toxic or harmful||Environment Canada Domestic Substance List|
|Classified as toxic or harmful||CPS&Q - Classification & Labelling|
|Limited evidence of cardiovascular or blood toxicity||Scorecard.org Toxicity Information|
|One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)||EPA Toxic Release Inventory PBTs|
|One or more animal studies show any effects at moderate doses (low dose studies may be unavailable for this ingredient)||EPA Categorized List of Inert Pesticide Ingredients|
|Allowed workplace exposures restricted to low doses||CPS&Q - Classification & Labelling|
|Human immune and respiratory toxicant or allergen - strong evidence||Association of Occupational and Environmental Clinics|
|Human skin toxicant or allergen - strong evidence||Cosmetic Ingredient Review Assessments|
|Limited evidence of immune system toxicity or allergies||National Library of Medicine HazMap|
|Possible human carcinogen||Open scientific literature|
|Possible human carcinogen||California EPA Proposition 65|
|Limited evidence of carcinogenicity||Open scientific literature|
|Limited evidence of carcinogenicity||Int'l Agency for Research on Cancer (IARC) - Carcinogens|
|Cancer - limited evidence||Scorecard.org Toxicity Information|
|Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gaps||Int'l Agency for Research on Cancer (IARC) - Carcinogens|
|One or more animal studies show neurodevelopmental effects at moderate doses||Open scientific literature|
|2147 studies in PubMed science library may include information on the toxicity of this chemical||NLM PubMed|
- CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
- NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
- Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
- European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
- CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
- EPA (U.S. Environmental Protection Agency). 2005. Office of Air. The 112(b)1 Hazardous Air Pollutants List (as modified). Last modified: 12 Dec 2005.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- ED (Environmental Defense). 2006. Scorecard _ The Pollution Information Site. http://www.scorecard.org.
- EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
- EPA (U.S. Environmental Protection Agency). 1987 & 2005. Office of Pesticide Programs. Inert (other) Pesticide Ingredients in Pesticide Products - Categorized List of Inert (other) Pesticide Ingredients.
- AOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
- Open scientific/peer reviewed literature
- California EPA (California Environmental Protection Agency). 9/2008. Office of Environmental Health Hazard Assessment. Safe Drinking Water and Toxic Enforcement Act of 1986. Chemicals known to the State to cause cancer or reproductive toxicity.
- IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.
Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.HOW WE DETERMINE SCORES
The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.
The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.