Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
|Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Unsafe in products left on skin and not rinsed off||Cosmetic Ingredient Review Assessments|
|Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications||Cosmetic Ingredient Review Assessments|
|Possible human any toxicant or allergen||Cosmetics Ingredient Review (CIR) 2010. Draft Final Amended Report on Cocamidopropyl Betaine and Related Amidopropyl Betaines. Pink Book 4, August 30-31, 2010.|
|One or more human case studies show significant sensitization or allergenic effects||Fowler JF, Fowler LM, Hunter JE Allergy to cocamidopropyl betaine may be due to amidoamine: A patch test and product use test study. Contact Dermatitis 1997;37:276-281.|
|Suspected to be an environmental toxin||Environment Canada Domestic Substance List|
|678 studies in PubMed science library may include information on the toxicity of this chemical||NLM PubMed|
|Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Unsafe in products left on skin and not rinsed off||Cosmetic Ingredient Review Assessments|
Organ system toxicity (non-reproductive)
|Classified as not expected to be potentially toxic or harmful||Environment Canada Domestic Substance List|
|Classified as a low human health priority||Environment Canada Domestic Substance List|
Persistence and bioaccumulation
|Not suspected to be persistent||Environment Canada Domestic Substance List|
|Not suspected to be bioaccumulative||Environment Canada Domestic Substance List|
- CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
- Cosmetics Ingredient Review (CIR) 2010. Draft Final Amended Report on Cocamidopropyl Betaine and Related Amidopropyl Betaines. Pink Book 4, August 30-31, 2010.
- Fowler JF, Fowler LM, Hunter JE Allergy to cocamidopropyl betaine may be due to amidoamine: A patch test and product use test study. Contact Dermatitis 1997;37:276-281.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- This ingredient’s score is higher if used in products that will not be immediately rinsed off due to increased risk of absorption.
- EWG VERIFIED products meet use restrictions and warnings based on EWG review of company data
ABOUT THE SKIN DEEP® RATINGS
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
ABOUT EWG VERIFIED™
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer