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Carbon black (Uncertified D&C Black No. 2)

Score:

Data: Robust

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (high), Neurotoxicity (low), Endocrine disruption (low), Persistence and bioaccumulation (moderate), Non-reproductive organ system toxicity (moderate), and Contamination concerns (high)

Cancer

Cancer concern is MODERATE

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW_MODERATE

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

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eye liner10 products
mask3 products
mascara2 products
eye shadow2 products
lip liner2 products
eyelash glue1 products

Contamination concerns

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Use restrictions

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Concern Reference
Violation of government restrictions - Banned or found unsafe for use in cosmeticsCTFA International Cosmetic Ingredient Dictionary and Handbook
Violation of government restrictions - Banned or found unsafe for use in cosmeticsFDA Color Additive Status
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive not approved by FDA for cosmetics used around eyesFDA Color Additive Status

Organ system toxicity (non-reproductive)

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Concern Reference
Possible human respiratory toxicantOpen scientific literature
Classified as a high human health priorityEnvironment Canada Domestic Substance List
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Classified as not expected to be potentially toxic or harmfulOpen scientific literature

Allergies/immunotoxicity

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Concern Reference
Possible human immune and respiratory toxicant or allergenOpen scientific literature

Persistence and bioaccumulation

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Concern Reference
Persistent or bioaccumulative and moderate to high toxicity concern in humansOpen scientific literature
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Cancer

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Concern Reference
Possible human carcinogenCalifornia EPA Proposition 65
Limited evidence of carcinogenicityNIOSH Occupational Carcinogens
Limited evidence of carcinogenicityInt'l Agency for Research on Cancer (IARC) - Carcinogens
Possible mutagenOpen scientific literature

Developmental/reproductive toxicity

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Concern Reference
Limited evidence of developmental/reproductive toxicityOpen scientific literature

Neurotoxicity

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Concern Reference
One or more animal studies show any effects at moderate dosesOpen scientific literature

Endocrine disruption

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Concern Reference
Associated with endocrine disruptionOpen scientific literature

Data gaps

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Concern Reference
994358 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color additive not approved by FDA for use in foodFDA Color Additive Status

Data Sources

  • CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
  • FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
  • Open scientific/peer reviewed literature
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • California EPA (California Environmental Protection Agency). 9/2008. Office of Environmental Health Hazard Assessment. Safe Drinking Water and Toxic Enforcement Act of 1986. Chemicals known to the State to cause cancer or reproductive toxicity.
  • NIOSH (National Institute for Occupational Safety and Health). 2006. NIOSH Carcinogens List (Potential occupational carcinogens). http://www.cdc.gov/niosh/npotocca.html.
  • IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

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