Menu Close Menu

Menu

Acid Violet 43 (Uncertified Ext. D&C Violet No. 2)

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (high), Non-reproductive organ system toxicity (moderate), Irritation (skin, eyes, or lungs) (low), and Contamination concerns (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

Expand content Collapse content
hair color and bleaching1 products
shampoo1 products
hair treatment/serum1 products

Contamination concerns

Expand content Collapse content

Use restrictions

Expand content Collapse content
Concern Reference
Violation of government restrictions - Banned or found unsafe for use in cosmeticsCTFA International Cosmetic Ingredient Dictionary and Handbook
Color additive not approved by FDA for cosmetics used around eyesUS. Food and Drug Administration (FDA). 2020. Color Additive Status. Appears as: ; Chemical_Name: ACID VIOLET 43; ;
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsIJT 20(S3):1-6, 2001

Allergies/immunotoxicity

Expand content Collapse content
Concern Reference
Human skin toxicant or allergen - strong evidenceEWG Assessment of Open Scientific Literature
Testing was inadequate to exclude the posibility for dermal sensitizaton.European Commission, Scientific Committee on Consumer Safety (SCCS) 2013. Opinion on Acid Violet 43 COLIPA n° C63.

Organ system toxicity (non-reproductive)

Expand content Collapse content
Concern Reference
Potential impacts on blood clotting observed in animal testing.European Commission, Scientific Committee on Consumer Safety (SCCS) 2013. Opinion on Acid Violet 43 COLIPA n° C63.
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Cancer

Expand content Collapse content
Concern Reference
Cancer - limited evidenceIJT 20(S3):1-6, 2001
Cancer - limited evidenceEWG Assessment of Open Scientific Literature
Genotoxicity reprorted in vitro tests.European Commission, Scientific Committee on Consumer Safety (SCCS) 2013. Opinion on Acid Violet 43 COLIPA n° C63.

Irritation (skin, eyes, or lungs)

Expand content Collapse content
Concern Reference
Causes serious eye damage.European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Sodium 4-[(9,10-dihydro-4-hydroxy-9,10-dioxo-1-anthryl)amino]toluene-3-sulphonate; sodium 2-[(4-hydroxy-9,10-dioxo-9,10-dihydroanthracen-1-yl)amino]-5-methylbenzene-1-sulfonate; Acid Violet 43; Benzenesulfonic acid, 2-((9,10-dihydro-4-hydroxy-9,10-dio; cas_numbers: 4430-18-6
Eye irritation reported from limited animal testing.European Commission, Scientific Committee on Consumer Safety (SCCS) 2013. Opinion on Acid Violet 43 COLIPA n° C63.

Data gaps

Expand content Collapse content
Concern Reference
192 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

Expand content Collapse content
Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Informational

Expand content Collapse content
Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyIJT 20(S3):1-6, 2001; Final report 12/2016 available from CIR

Persistence and bioaccumulation

Expand content Collapse content
Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
  • US. Food and Drug Administration (FDA). 2020. Color Additive Status. Appears as: ; Chemical_Name: ACID VIOLET 43; ;
  • IJT 20(S3):1-6, 2001
  • EWG Assessment of Open Scientific Literature
  • European Commission, Scientific Committee on Consumer Safety (SCCS) 2013. Opinion on Acid Violet 43 COLIPA n° C63.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Sodium 4-[(9,10-dihydro-4-hydroxy-9,10-dioxo-1-anthryl)amino]toluene-3-sulphonate; sodium 2-[(4-hydroxy-9,10-dioxo-9,10-dihydroanthracen-1-yl)amino]-5-methylbenzene-1-sulfonate; Acid Violet 43; Benzenesulfonic acid, 2-((9,10-dihydro-4-hydroxy-9,10-dio; cas_numbers: 4430-18-6
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • IJT 20(S3):1-6, 2001; Final report 12/2016 available from CIR

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

ABOUT EWG VERIFIED™

Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer