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Data: Fair

Acid Red 33 (Uncertified D&C Red No. 33)

IMAGE SOURCE: PubChem

SEARCH PRODUCTS

Other Concerns

Use restrictions (high) and Contamination concerns (high)

SYNONYMS

● 2,7-NAPHTHALENEDISULFONIC ACID, 5-AMINO-4-HYDROXY-3-(PHENYLAZO)-, DISODIUM SALT
● 5-AMINO-4-HYDROXY-3-(PHENYLAZO)- DISODIUM SALT 2,7-NAPHTHALENEDISULFONIC ACID
● 5-AMINO-4-HYDROXY-3-(PHENYLAZO)-2,7-NAPHTHALENEDISULFONIC ACID, DISODIUM SALT
● ACID RED 33
● ACID RED 33 (UNCERTIFIED D&C RED NO. 33)
● DISODIUM SALT 2,7-NAPHTHALENEDISULFONIC ACID, 5-AMINO-4-HYDROXY-3-(PHENYLAZO)-
● DISODIUM SALT 5-AMINO-4-HYDROXY-3-(PHENYLAZO)-2,7-NAPHTHALENEDISULFONIC ACID
● FAST ACID FUCHSINE B
● FOOD RED 12
● RED 227
● RED NO. 227

Unacceptable

Unacceptable: EWG VERIFIED products cannot contain this ingredient


Acid Red 33 is classed chemically as a monoazo color.

Common concerns

See how this product scores for common concerns.

  • MODERATE
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • HIGH
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

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bath oil/salts/soak1 products
hair treatment/serum1 products

Contamination concerns

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Use restrictions

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CONCERN REFERENCE
Violation of government restrictions - Banned or found unsafe for use in cosmeticsCTFA International Cosmetic Ingredient Dictionary and Handbook
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - anyOpen scientific literature

Cancer

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CONCERN REFERENCE
Limited evidence of carcinogenicityOpen scientific literature
Not likely to be mutagenic in humansOpen scientific literature
Not likely to be carcinogenic in humansOpen scientific literature

Allergies/immunotoxicity

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CONCERN REFERENCE
One or more animal studies show any or allergenic effects at moderate dosesOpen scientific literature

Ecotoxicology

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CONCERN REFERENCE
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Developmental/reproductive toxicity

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CONCERN REFERENCE
Not likely to be a any toxicant in humansOpen scientific literature

Data gaps

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CONCERN REFERENCE
6 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Informational

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CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyOpen scientific literature
  • CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
  • Open scientific/peer reviewed literature
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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