Menu Close Menu

Menu

5-AMINO-6-CHLORO-O-CRESOL

Score:

Data: None

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

Expand content Collapse content
hair color and bleaching1 products

Allergies/immunotoxicity

Expand content Collapse content
Concern Reference
Human skin toxicant or allergen - strong evidenceIJT 23(S2):1-22, 2004
Human skin toxicant or allergen - strong evidenceEWG Assessment of Open Scientific Literature

Use restrictions

Expand content Collapse content
Concern Reference
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - anyHealth Canada 2011. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2011.
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panelIJT 23(S2):1-22, 2004
Determined safe for use in cosmetics, subject to concentration or use limitations - anyCTFA International Cosmetic Ingredient Dictionary and Handbook

Cancer

Expand content Collapse content
Concern Reference
Cancer - limited evidenceIJT 23(S2):1-22, 2004
Cancer - limited evidenceEWG Assessment of Open Scientific Literature
Cancer - limited evidenceCTFA International Cosmetic Ingredient Dictionary and Handbook

Data gaps

Expand content Collapse content
Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productIJT 23(S2):1-22, 2004
Considered safe based on assumption of low absorptionIJT 23(S2):1-22, 2004
Missing safety data noted by cosmetic industry reviewIJT 23(S2):1-22, 2004
Insufficient data to determine safetyFinal Report 3/04 Available from CIR
1 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Informational

Expand content Collapse content
Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyIJT 23(S2):1-22, 2004

Data Sources

  • IJT 23(S2):1-22, 2004
  • EWG Assessment of Open Scientific Literature
  • Health Canada 2011. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2011.
  • CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
  • Final Report 3/04 Available from CIR
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

ABOUT EWG VERIFIED™

Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer