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BETAINE

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Multiple, additive exposure sources (low) and Irritation (skin, eyes, or lungs) (low)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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mask151 products
serums & essences102 products
facial moisturizer/treatment102 products
shampoo45 products
lipstick36 products
facial cleanser35 products
moisturizer28 products
conditioner27 products
toners/astringents26 products
daily use with SPF20 products
lip gloss17 products
around-eye cream17 products
body wash/cleanser15 products
hair treatment/serum15 products
exfoliant/scrub12 products
liquid hand soap11 products
hair color and bleaching11 products
concealer11 products
anti-aging9 products
makeup primer9 products
hair styling aide8 products
body firming lotion6 products
BB cream6 products
makeup remover6 products
hand cream5 products
toothpaste5 products
facial powder5 products
baby wipes5 products
bronzer/highlighter4 products
detangler4 products
setting powder/spray4 products
recreational sunscreen3 products
bar soap3 products
baby shampoo3 products
foot moisturizer3 products
lip balm2 products
blush2 products
eye makeup remover2 products
lip plumper1 products
mascara1 products
damaged skin treatment1 products
hair spray1 products
1 products
body powder1 products
sunless tanning1 products
foot cleansing1 products
glitter1 products
body spray1 products
pore strips1 products
styling gel/lotion1 products
bubble bath1 products
baby bubble bath1 products
hand sanitizer1 products
mouthwash1 products
baby soap1 products

Multiple, additive exposure sources

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Concern Reference
Used in food or as an additive with limited or no toxicity information availableFDA Everything Added to Food

Irritation (skin, eyes, or lungs)

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Concern Reference
Safe for use when formulated to be non-irritatingCosmetic Ingredient Review (CIR) 2020. CIR Assessments. Appears as: ; Chemical_Name: BETAINE; ; CAS: 107-43-7; Classification: QQQ53; I;
CLP notification: this substance causes skin irritationEuropean Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Betaine; 2-(trimethylazaniumyl)acetate; (Carboxymethyl)trimethylammonium inner salt, Oxyneurine, Trimethylglycine; (trimethylammonio)acetate; 2-(trimethylazaniumyl)acetate; Betaine; Betaine; BETAFIN®; BetaFrost®; GREENSTIM; NATURAL EXTRACT AP; NATUR; cas_numbers: 107-43-7

Data gaps

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Concern Reference
5710 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • Cosmetic Ingredient Review (CIR) 2020. CIR Assessments. Appears as: ; Chemical_Name: BETAINE; ; CAS: 107-43-7; Classification: QQQ53; I;
  • European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Betaine; 2-(trimethylazaniumyl)acetate; (Carboxymethyl)trimethylammonium inner salt, Oxyneurine, Trimethylglycine; (trimethylammonio)acetate; 2-(trimethylazaniumyl)acetate; Betaine; Betaine; BETAFIN®; BetaFrost®; GREENSTIM; NATURAL EXTRACT AP; NATUR; cas_numbers: 107-43-7
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.

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