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Data: Fair

Betaine

IMAGE SOURCE: PubChem

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Other Concerns

Multiple, additive exposure sources (low) and Irritation (skin, eyes, or lungs) (low)

SYNONYMS

1-CARBOXY-N,N,N-TRIMETHYL- HYDROXIDE INNER SALT METHANAMINIUM, 1-CARBOXY-N,N,N-TRIMETHYLMETHANAMINIUM HYDROXIDE, INNER SALT, 2-(TRIMETHYLAMMONIO)ETHANOIC ACID, HYDROXIDE, INNER SALT, BETAINE, HYDROXIDE INNER SALT METHANAMINIUM, 1-CARBOXY-N,N,N-TRIMETHYL-, INNER SALT 1-CARBOXY-N,N,N-TRIMETHYLMETHANAMINIUM HYDROXIDE, INNER SALT METHANAMINIUM, 1-CARBOXY-N,N,N-TRIMETHYL-, HYDROXIDE, METHANAMINIUM, 1-CARBOXY-N,N,N-TRIMETHYL-, HYDROXIDE, INNER SALT, METHANAMINIUM, 1-CARBOXY-N,N,N-TRIMETHYL-, INNER SALT, METHANAMINIUM, 1CARBOXYN,N,NTRIMETHYL, HYDROXIDE, INNERSALT, and TRIMETHYLGLYCINE

Betaine is a zwitterion (inner salt).

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • LOW
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

Expand content Collapse content
mask211 products
facial moisturizer/treatment158 products
serums & essences85 products
shampoo71 products
toners/astringents53 products
facial cleanser50 products
moisturizer42 products
conditioner41 products
around-eye cream36 products
lipstick26 products
hair treatment/serum23 products
daily use with SPF20 products
hair color and bleaching19 products
anti-aging19 products
foundation18 products
makeup primer14 products
makeup remover13 products
exfoliant/scrub13 products
hair styling aide13 products
bar soap9 products
foot cleansing9 products
liquid hand soap9 products
body wash/cleanser9 products
BB cream8 products
setting powder/spray7 products
toothpaste7 products
lip balm7 products
baby wipes6 products
styling gel/lotion6 products
hand cream5 products
foot moisturizer5 products
detangler4 products
lip gloss4 products
eye shadow4 products
sunless tanning3 products
3 products
baby shampoo3 products
facial powder3 products
recreational sunscreen3 products
body firming lotion2 products
bronzer/highlighter2 products
beard care2 products
nail treatment2 products
skin fading/lightener2 products
hand sanitizer2 products
mouthwash2 products
bubble bath2 products
lip plumper1 products
baby toothpaste1 products
body oil1 products
hair-loss treatment1 products
glitter1 products
body powder1 products
body spray1 products
mascara1 products
other eye makeup1 products
damaged skin treatment1 products
eye makeup remover1 products
after sun product1 products
bath oil/salts/soak1 products
styling mousse/foam1 products
pore strips1 products
baby bubble bath1 products

Multiple, additive exposure sources

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CONCERN REFERENCE
Used in food or as an additive with limited or no toxicity information availableFDA Everything Added to Food

Irritation (skin, eyes, or lungs)

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CONCERN REFERENCE
Limited evidence of any irritationOpen scientific literature
any irritation - weight of evidence unknown/unassessedOpen scientific literature

Ecotoxicology

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CONCERN REFERENCE
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data gaps

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CONCERN REFERENCE
5710 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • Open scientific/peer reviewed literature
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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