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BETAINE

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Multiple, additive exposure sources (low) and Irritation (skin, eyes, or lungs) (low)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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mask204 products
facial moisturizer/treatment124 products
serums & essences75 products
shampoo62 products
facial cleanser48 products
toners/astringents48 products
conditioner39 products
moisturizer36 products
around-eye cream29 products
daily use with SPF22 products
hair treatment/serum21 products
foundation18 products
makeup primer16 products
hair styling aide15 products
makeup remover15 products
body firming lotion14 products
exfoliant/scrub14 products
hair color and bleaching13 products
liquid hand soap13 products
body wash/cleanser12 products
anti-aging12 products
BB cream8 products
concealer8 products
foot cleansing7 products
setting powder/spray7 products
toothpaste7 products
bar soap7 products
baby wipes7 products
hand cream5 products
foot moisturizer5 products
lip balm4 products
detangler4 products
eye shadow4 products
3 products
baby shampoo3 products
styling gel/lotion3 products
facial powder3 products
recreational sunscreen3 products
bronzer/highlighter3 products
body spray2 products
blush2 products
nail treatment2 products
sunless tanning2 products
eye makeup remover2 products
mouthwash2 products
body oil2 products
mascara2 products
styling mousse/foam2 products
hair-loss treatment2 products
damaged skin treatment1 products
other eye makeup1 products
lip plumper1 products
glitter1 products
body powder1 products
beard care1 products
skin fading/lightener1 products
beard cleanser1 products
hair spray1 products
bubble bath1 products
pore strips1 products
hand sanitizer1 products

Multiple, additive exposure sources

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Concern Reference
Used in food or as an additive with limited or no toxicity information availableFDA Everything Added to Food

Irritation (skin, eyes, or lungs)

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Concern Reference
Safe for use when formulated to be non-irritatingCosmetic Ingredient Review (CIR) 2020. CIR Assessments. Appears as: ; Chemical_Name: BETAINE; ; CAS: 107-43-7; Classification: QQQ53; I;
CLP notification: this substance causes skin irritationEuropean Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Betaine; 2-(trimethylazaniumyl)acetate; (Carboxymethyl)trimethylammonium inner salt, Oxyneurine, Trimethylglycine; (trimethylammonio)acetate; 2-(trimethylazaniumyl)acetate; Betaine; Betaine; BETAFIN®; BetaFrost®; GREENSTIM; NATURAL EXTRACT AP; NATUR; cas_numbers: 107-43-7

Data gaps

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Concern Reference
5710 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • Cosmetic Ingredient Review (CIR) 2020. CIR Assessments. Appears as: ; Chemical_Name: BETAINE; ; CAS: 107-43-7; Classification: QQQ53; I;
  • European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Betaine; 2-(trimethylazaniumyl)acetate; (Carboxymethyl)trimethylammonium inner salt, Oxyneurine, Trimethylglycine; (trimethylammonio)acetate; 2-(trimethylazaniumyl)acetate; Betaine; Betaine; BETAFIN®; BetaFrost®; GREENSTIM; NATURAL EXTRACT AP; NATUR; cas_numbers: 107-43-7
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.

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