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ZINC PYRITHIONE

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (high), Persistence and bioaccumulation (moderate), Non-reproductive organ system toxicity (moderate), and Ecotoxicology (low)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW_MODERATE

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW_MODERATE

Products with this Ingredient

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conditioner2 products
antiperspirant/deodorant1 products
shampoo1 products

Use restrictions

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Concern Reference
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - anyCosIng, EU Cosmetics Directive
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - anyCosIng
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)Japan's Standards for Cosmetics

Persistence and bioaccumulation

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Concern Reference
Persistent or bioaccumulative and moderate to high toxicity concern in humansEnvironment Canada Domestic Substance List
Persistent, bioaccumulative in wildlifeCanada PBTs - Accelerated Reduction/Elimination of Toxics (ARET)
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Developmental/reproductive toxicity

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Concern Reference
Possible human reproductive or developmental toxinGHS Data from ECHA Website, European Chemicals Agency (ECHA)

Allergies/immunotoxicity

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Concern Reference
Limited evidence of any toxicity or allergiesGHS Data from ECHA Website, European Chemicals Agency (ECHA)

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Limited evidence of respiratory toxicityCalifornia EPA, Office of Environmental Health Hazard Assessment Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)EPA Toxic Release Inventory PBTs
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Ecotoxicology

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Concern Reference
Suspected to be an environmental toxin and be persistent or bioaccumulativeEnvironment Canada Domestic Substance List
Suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
248 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Data Sources

  • CosIng, EU Cosmetics Directive
  • European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
  • Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • EC (Environment Canada). 1994. Accelerated Reduction/Elimination of Toxics (ARET). ARET substance list of persistent, bioaccumulative and toxic chemicals.
  • GHS Data from ECHA Website, European Chemicals Agency (ECHA)
  • California EPA, Office of Environmental Health Hazard Assessment Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document
  • EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

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