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ZINC OXIDE

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Persistence and bioaccumulation (moderate), Non-reproductive organ system toxicity (moderate), Ecotoxicology (low), and Occupational hazards (moderate)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW_MODERATE

Products with this Ingredient

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foundation269 products
concealer99 products
daily use with SPF52 products
antiperspirant/deodorant43 products
facial powder42 products
lip liner38 products
lipstick37 products
facial moisturizer/treatment31 products
BB cream23 products
18 products
blush18 products
mask15 products
body powder14 products
diaper cream14 products
makeup primer14 products
nail polish12 products
eye shadow12 products
moisturizer11 products
eye liner10 products
lip gloss10 products
toothpaste9 products
hair color and bleaching8 products
anti-aging8 products
setting powder/spray8 products
bronzer/highlighter8 products
lip balm8 products
serums & essences5 products
around-eye cream5 products
facial cleanser5 products
body wash/cleanser4 products
antiperspirant/deodorant (men's)4 products
baby lotion3 products
body spray3 products
exfoliant/scrub3 products
foot odor control3 products
bar soap3 products
body firming lotion2 products
recreational sunscreen2 products
skin fading/lightener2 products
shampoo2 products
shaving cream2 products
shaving cream (men's)1 products
mascara1 products
baby sunscreen1 products
damaged skin treatment1 products
bath oil/salts/soak1 products
after shave1 products
brow liner1 products
lip balm with SPF1 products
hand cream1 products
tooth whitening1 products
toners/astringents1 products
depilatory1 products

Enhanced skin absorption

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Concern Reference
Does not cause enhanced penetrationOpen scientific literature

Occupational hazards

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Concern Reference
Strong evidence of occupational hazardsOpen scientific literature
Allowed workplace exposures restricted to moderate dosesNational Library of Medicine HazMap

Persistence and bioaccumulation

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Concern Reference
Persistent, bioaccumulative in wildlifeCanada PBTs - Accelerated Reduction/Elimination of Toxics (ARET)
Found to be persistent and bioaccumulative in wildlifeOpen scientific literature

Decreased skin absorption

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Concern Reference
Limited potential to absorb into the skin.Open scientific literature

Organ system toxicity (non-reproductive)

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Concern Reference
Possible human respiratory toxicantAssociation of Occupational and Environmental Clinics
Limited evidence of any toxicityScorecard.org Toxicity Information
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)EPA Toxic Release Inventory PBTs

Allergies/immunotoxicity

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Concern Reference
One or more animal studies show any or allergenic effects at very low dosesOpen scientific literature

Ecotoxicology

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Concern Reference
Wildlife and environmental toxicityCPS&Q - Classification & Labelling
Wildlife and environmental toxicityOpen scientific literature

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color additive approved by FDA for use in cosmeticsFDA Color Additive Status
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives - Exempt from Batch Certification by the U.S. Food and Drug AdministrationCTFA International Cosmetic Ingredient Dictionary and Handbook

Developmental/reproductive toxicity

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Concern Reference
Not likely to be a reproductive toxicant in humansOpen scientific literature

Data gaps

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Concern Reference
6924 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Data Sources

  • Open scientific/peer reviewed literature
  • NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
  • EC (Environment Canada). 1994. Accelerated Reduction/Elimination of Toxics (ARET). ARET substance list of persistent, bioaccumulative and toxic chemicals.
  • AOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
  • ED (Environmental Defense). 2006. Scorecard _ The Pollution Information Site. http://www.scorecard.org.
  • EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
  • CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About this Ingredient's Score Range

  • This ingredient’s score is higher if used in products that are inhalable (e.g., sprays, powders) because of respiratory concerns.

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