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UREA

Score:

Data: Good

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Enhanced skin absorption and Use restrictions (moderate)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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foundation87 products
concealer40 products
mask34 products
daily use with SPF32 products
facial moisturizer/treatment27 products
moisturizer25 products
serums & essences24 products
foot moisturizer21 products
toners/astringents15 products
BB cream14 products
bronzer/highlighter11 products
foot cleansing10 products
facial cleanser9 products
hand cream9 products
exfoliant/scrub8 products
conditioner8 products
body wash/cleanser8 products
body firming lotion7 products
shampoo7 products
depilatory7 products
hair treatment/serum5 products
hair color and bleaching4 products
recreational sunscreen3 products
makeup primer3 products
3 products
anti-aging3 products
around-eye cream3 products
foot odor control3 products
beard care2 products
nail treatment2 products
eye liner2 products
cuticle treatment2 products
makeup remover2 products
hair-loss treatment1 products
damaged skin treatment1 products
bar soap1 products
lipstick1 products
shaving cream1 products
facial powder1 products
eyelash glue1 products
hair styling aide1 products
antiperspirant/deodorant1 products
depilatory (men's)1 products
hand sanitizer1 products
oil controller1 products
mascara1 products
bath oil/salts/soak1 products

Enhanced skin absorption

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Concern Reference
Penetration enhancerCosmetic Ingredient Review Assessments

Use restrictions

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Concern Reference
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmeticsCanada - Prohibited and Restricted Cosmetics Ingredients

Cancer

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Concern Reference
A 2011 EPA evaluation found inadequate information to assess the carcinogenic potential of urea.US Environmental Protection Agency 2010. Toxicological Review of Urea (CAS No. 57-13-6). EPA/635/R-10/005F.

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
A 2011 EPA evaluation found inadequate information to assess the carcinogenic potential of urea.US Environmental Protection Agency 2010. Toxicological Review of Urea (CAS No. 57-13-6). EPA/635/R-10/005F.
94887 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
  • US Environmental Protection Agency 2010. Toxicological Review of Urea (CAS No. 57-13-6). EPA/635/R-10/005F.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

About this Ingredient's Score Range

  • Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

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Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer