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Data: Fair

Tromethamine

  • Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data.

IMAGE SOURCE: PubChem

SEARCH PRODUCTS

Other Concerns

Use restrictions (moderate)

SYNONYMS

1,3-PROPANEDIOL, 2-AMINO-2-(HYDROXYMETHYL)-, 1,3PROPANEDIOL, 2AMINO2(HYDROXYMETHYL), 2-AMINO-2-(HYDROXYMETHYL)- 1,3-PROPANEDIOL, 2-AMINO-2-(HYDROXYMETHYL)-1,3-PROPANEDIOL, THAM, TRIS(HYDROXYMETHYL)AMINO METHANE, TRIS; TRIS, FREE BASE, TROMETAMOL, and TROMETHAMINE

Restricted

Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation


Tromethamine is an aliphatic compound.

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • MODERATE
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

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facial moisturizer/treatment93 products
mask92 products
foundation48 products
serums & essences47 products
around-eye cream21 products
moisturizer20 products
toners/astringents18 products
mascara14 products
facial cleanser13 products
exfoliant/scrub8 products
daily use with SPF8 products
makeup primer8 products
eye liner7 products
body firming lotion6 products
anti-aging5 products
hand sanitizer5 products
brow liner3 products
hand cream3 products
foot moisturizer3 products
makeup remover2 products
hair treatment/serum2 products
foot cleansing2 products
BB cream2 products
lipstick2 products
skin fading/lightener2 products
tooth whitening1 products
foot odor control1 products
1 products
setting powder/spray1 products
body spray1 products
baby lotion1 products
cuticle treatment1 products
eye shadow1 products
concealer1 products
bronzer/highlighter1 products
hair styling aide1 products
recreational sunscreen1 products

Use restrictions

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CONCERN REFERENCE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - anyCosIng

Ecotoxicology

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CONCERN REFERENCE
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Informational

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CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Data gaps

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CONCERN REFERENCE
5873 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed
  • European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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