EWG Skin Deep® | What is TRICLOCARBAN

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Data: Fair

Triclocarban

IMAGE SOURCE: PubChem

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Other Concerns

Use restrictions (high), Endocrine disruption (low_moderate), Persistence and bioaccumulation (moderate), Non-reproductive organ system toxicity (low_moderate), and Ecotoxicology (low)

SYNONYMS

● 3,4,4` TRICHLOROCARBANILIDE (TRICLOCARBAN)

● FT-0614114

● Q416579

● SMR001339078

● 3,4,4` TRICHLOROCARBANILIDE (TRICLOCARBAN), PHARMACEUTICAL SECONDARY STANDARD; CERTIFIED REFERENCE MATERIAL

● NCGC00259579-01

● J10256

● AC-12602

● 3-(4-CHLOROPHENYL)-1-(3,4-DICHLOROPHENYL)UREA

● D06223

Unacceptable

Unacceptable: EWG VERIFIED products cannot contain this ingredient

Triclocarban is a substituted carbanilide.

Common concerns

See how this product scores for common concerns.

LOW

Cancer
LOW

Allergies & Immunotoxicity
LOW

Developmental and Reproductive Toxicity
HIGH

Use Restrictions

Ingredient concerns

CONCERNS
DATA SOURCES

Products with this Ingredient

antiperspirant/deodorant	3 products
bar soap	7 products

Developmental/reproductive toxicity

CONCERN	REFERENCE
One or more animal studies show reproductive effects at high doses	Triclocarban enhances testosterone action: a new type of endocrine disruptor?(2008-03-01)

Endocrine disruption

CONCERN	REFERENCE
Associated with endocrine disruption	Triclocarban enhances testosterone action: a new type of endocrine disruptor?(2008-03-01)
Limited evidence of disruption	The in vitro estrogenic activities of triclosan and triclocarban(2014-09-01)
One or more studies show significant endocrine disruption	Safety and Effectiveness of Consumer Antiseptics; Topical Antimicrobial Drug Products for Over-the-Counter Human Use; Proposed Amendment of the Tentative Final Monograph; Reopening of Administrative Record(2013-12-17)

Enhanced skin absorption

CONCERN	REFERENCE
Absorbs into the skin	Predictability of in vitro diffusion systems: Effect of skin types and ages on percutaneous absorption of Triclocarban(1985-01-01)
Absorbs into the skin	Safety and Effectiveness of Consumer Antiseptics; Topical Antimicrobial Drug Products for Over-the-Counter Human Use; Proposed Amendment of the Tentative Final Monograph; Reopening of Administrative Record(2013-12-17)

Organ system toxicity (non-reproductive)

CONCERN	REFERENCE
One or more animal studies show blood and liver effects at moderate doses (low dose studies may be unavailable for this ingredient)	A twenty-four month dietary toxicity/carcinogenicity study of Triclocarban in rats (Report no BDN-77-280)(1981-01-01)
Classified as expected to be toxic or harmful	Environment Canada

Use restrictions

CONCERN	REFERENCE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions -	Cosmetics Directive(2012-01-01)
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - any	EU Cosmetics Directive

Ecotoxicology

CONCERN	REFERENCE
Suspected to be an environmental toxin	Environment Canada
Suspected to be an environmental toxin	Environment Canada

Persistence and bioaccumulation

CONCERN	REFERENCE
Not suspected to be bioaccumulative	Environment Canada
Persistent, bioaccumulative in wildlife	OSPAR Comission
Persistent or bioaccumulative and moderate to high toxicity concern in humans	Organohalogen Pollutants and Human Health(2017-01-01)

Triclocarban enhances testosterone action: a new type of endocrine disruptor?(2008-03-01)
The in vitro estrogenic activities of triclosan and triclocarban(2014-09-01)
Safety and Effectiveness of Consumer Antiseptics; Topical Antimicrobial Drug Products for Over-the-Counter Human Use; Proposed Amendment of the Tentative Final Monograph; Reopening of Administrative Record(2013-12-17)
Predictability of in vitro diffusion systems: Effect of skin types and ages on percutaneous absorption of Triclocarban(1985-01-01)
A twenty-four month dietary toxicity/carcinogenicity study of Triclocarban in rats (Report no BDN-77-280)(1981-01-01)
Environment Canada
Cosmetics Directive(2012-01-01)
EU Cosmetics Directive
OSPAR Comission
Organohalogen Pollutants and Human Health(2017-01-01)

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG Verified^® mark means a product meets EWG’s strictest criteria for transparency and health.

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST

Low Availability

Moderate Availability

High Availability