Menu Close Menu

Menu

TRICLOCARBAN

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (moderate), Endocrine disruption (low), Persistence and bioaccumulation (moderate), Non-reproductive organ system toxicity (moderate), and Ecotoxicology (low)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

Expand content Collapse content

Enhanced skin absorption

Expand content Collapse content
Concern Reference
Absorbs into the skinWester RC, Maibach HI, Surinchak J, Bucks DAW Predictability of in vitro diffusion systems: Effect of skin types and ages on percutaneous absorption of Triclocarban. Dermatol. 1985; 6:223-6.

Persistence and bioaccumulation

Expand content Collapse content
Concern Reference
Persistent, bioaccumulative in wildlifeOSPAR PBTs - Substances of Possible Concern
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Use restrictions

Expand content Collapse content
Concern Reference
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - anyCosIng
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - anyEuropean Union Cosmetics Directive

Organ system toxicity (non-reproductive)

Expand content Collapse content
Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
One or more animal studies show blood and liver effects at moderate doses (low dose studies may be unavailable for this ingredient)Monsanto A twenty-four month dietary toxicity/carcinogenicity study of Triclocarban in rats. 1981. Report no. BDN-77-280.

Developmental/reproductive toxicity

Expand content Collapse content
Concern Reference
One or more animal studies show reproductive effects at high dosesChen J, Ahn KC, Gee NA, Ahmed MI, Duleba AJ, Zhao L, Gee SJ, Hammock BD, Lasley BL Triclocarban enhances testosterone action: a new type of endocrine disruptor? Endocrinology. 2008 Mar;149(3):1173-9.

Ecotoxicology

Expand content Collapse content
Concern Reference
Suspected to be an environmental toxin and be persistent or bioaccumulativeEnvironment Canada Domestic Substance List
Suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Endocrine disruption

Expand content Collapse content
Concern Reference
Associated with endocrine disruptionChen J, Ahn KC, Gee NA, Ahmed MI, Duleba AJ, Zhao L, Gee SJ, Hammock BD, Lasley BL Triclocarban enhances testosterone action: a new type of endocrine disruptor? Endocrinology. 2008 Mar;149(3):1173-9.

Data gaps

Expand content Collapse content
Concern Reference
3752 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Data Sources

  • Wester RC, Maibach HI, Surinchak J, Bucks DAW Predictability of in vitro diffusion systems: Effect of skin types and ages on percutaneous absorption of Triclocarban. Dermatol. 1985; 6:223-6.
  • OSPAR (Oslo-Paris). 2002. OSPAR List of Substances of Possible Concern. Secondary OSPAR List of Substances of Possible Concern. Secondary OSPAR. Place Published, OSPAR Convention for the Protection of the Marine Environement of North-East Atlanic.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
  • European Union Cosmetics Directive
  • Monsanto A twenty-four month dietary toxicity/carcinogenicity study of Triclocarban in rats. 1981. Report no. BDN-77-280.
  • Chen J, Ahn KC, Gee NA, Ahmed MI, Duleba AJ, Zhao L, Gee SJ, Hammock BD, Lasley BL Triclocarban enhances testosterone action: a new type of endocrine disruptor? Endocrinology. 2008 Mar;149(3):1173-9.
  • Chen J, Ahn KC, Gee NA, Ahmed MI, Duleba AJ, Zhao L, Gee SJ, Hammock BD, Lasley BL Triclocarban enhances testosterone action: a new type of endocrine disruptor? Endocrinology. 2008 Mar;149(3):1173-9.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

ABOUT EWG VERIFIED™

Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer