Know Your Environment. Protect Your Health.
EWG Home EWG’s Guide to Healthy Cleaning EWG’s Food Scores Healthy Living App Open menu

EWG's Skin Deep®
Find products and ingredients Learn how Skin Deep® works Meet our experts Discover EWG VERIFIED®
GET UPDATES DONATE
Score legend
HOW WE DETERMINE SCORES Learn more About EWG VERIFIED®

Data: Limited

Toluene 2,5 Diamine

IMAGE SOURCE: PubChem

SEARCH PRODUCTS

Other Concerns

Enhanced skin absorption, Use restrictions (high), Non-reproductive organ system toxicity (low_moderate), Ecotoxicology (low), and Occupational hazards (moderate)

SYNONYMS

● TOLUYLEN-2,5-DIAMIN
● 2,5-DIAMINO TOLUENE FREE
● (4-AMINO-2-METHYL-PHENYL)-AMINE
● ZINC388337
● ACT07295
● KS-000025XA
● ANW-52954
● 2,5-DIAMINO TOLUENE
● MFCD00035779
● UNII-NJX12DY6BY COMPONENT OBCSAIDCZQSFQH-UHFFFAOYSA-N

Unacceptable

Unacceptable: EWG VERIFIED products cannot contain this ingredient

Toluene-2, 5-Diamine is a substituted aromatic amine.

Common concerns

See how this product scores for common concerns.

  • LOW_MODERATE
    Cancer
  • HIGH
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • HIGH
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

Expand content Collapse content
hair color and bleaching49 products

Allergies/immunotoxicity

Expand content Collapse content
CONCERN REFERENCE
Known human toxicant or allergenOpinion on Toluene-2,5-diamine and its sulfate, COLIPA n A5(2012-06-01)
Possible human dermal toxicant or allergenEU GHS Hazard Labeling Codes
Limited evidence of immune system toxicity or allergiesEU GHS Hazard Labeling Codes
Human skin toxicant or allergen - strong evidenceCosmetic Ingredient Review (CIR)
Limited evidence of immune system toxicity or allergiesUS National Library of Medicine,

Cancer

Expand content Collapse content
CONCERN REFERENCE
Not likely to be carcinogenic in humansInternational Agency for Research on Cancer (IARC)
Not likely to be carcinogenic in humansCosmetic Ingredient Review (CIR)
Cancer - limited evidencePersonal Care Products Council
Limited evidence of carcinogenicityInternational Agency for Research on Cancer (IARC)

Ecotoxicology

Expand content Collapse content
CONCERN REFERENCE
Wildlife and environmental toxicityEU GHS Hazard Labeling Codes

Organ system toxicity (non-reproductive)

Expand content Collapse content
CONCERN REFERENCE
Classified as toxic or harmfulEU GHS Hazard Labeling Codes

Occupational hazards

Expand content Collapse content
CONCERN REFERENCE
Allowed workplace exposures restricted to low dosesEU GHS Hazard Labeling Codes

Use restrictions

Expand content Collapse content
CONCERN REFERENCE
Violation of government restrictions - Banned or found unsafe for use in cosmeticsHealth Canada
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - anyEU Cosmetics Directive
Determined safe for use in cosmetics, subject to concentration or use limitations - anyPersonal Care Products Council

Data gaps

Expand content Collapse content
CONCERN REFERENCE
Risk assessment method deficiencies and data gaps - Maximum reported 'as used' concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review (CIR)

Informational

Expand content Collapse content
CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review (CIR)
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives - Hair DyePersonal Care Products Council
  • Opinion on Toluene-2,5-diamine and its sulfate, COLIPA n A5(2012-06-01)
  • EU GHS Hazard Labeling Codes
  • Cosmetic Ingredient Review (CIR)
  • US National Library of Medicine,
  • International Agency for Research on Cancer (IARC)
  • Personal Care Products Council
  • Health Canada
  • EU Cosmetics Directive

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.


HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend
WEIGHT-OF-EVIDENCE APPROACH

A product’s hazard score is not an average of the ingredients’ hazard scores. It is calculated using a weight-of-evidence approach that factors in all of the hazards or health impacts associated with the ingredients.

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability
NONE

Ingredients have not been assessed.

LIMITED-FAIR

There is only a modest volume of research.

GOOD-ROBUST

Ingredients have been studied extensively.

Can’t find your product?

Enter the ingredients in EWG’s Build Your Own Report tool to get an approximate score for that product.

BUILD YOUR OWN REPORT

News & updates

Big Market for Black Cosmetics, but Less-Hazardous Choices Limited
RESEARCH
Big Market for Black Cosmetics, but Less-Hazardous Choices Limited
K-Beauty Trends: Serums, Essences and EWG’s Best Bets
RESEARCH
K-Beauty Trends: Serums, Essences and EWG’s Best Bets
FDA Asks Women To Protect Themselves From Products The Agency Refused To Ban
NEWS RELEASE
FDA Asks Women To Protect Themselves From Products The Agency Refused To Ban
Study Highlights Importance of Cosmetics Ingredient Safety Tests
NEWS RELEASE
Study Highlights Importance of Cosmetics Ingredient Safety Tests
READ ALL ARTICLES
EWG Holiday Gift Box

Sustainable Swaps

Start the giving season with a limited-edition gift box filled with eco-friendly products to help you reduce waste, eat cleaner, and shop smarter.

DONATE NOW