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TOCOPHERYL ACETATE

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Contamination concerns (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

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lipstick1476 products
foundation729 products
concealer511 products
lip gloss325 products
eye shadow317 products
moisturizer314 products
beach & sport sunscreen281 products
facial moisturizer/treatment261 products
conditioner250 products
bronzer/highlighter242 products
moisturizer with SPF240 products
blush230 products
serums & essences196 products
shampoo188 products
brow liner143 products
mask142 products
body wash/cleanser136 products
mascara116 products
lip balm112 products
liquid hand soap104 products
facial cleanser102 products
hair treatment/serum100 products
facial powder96 products
body firming lotion96 products
eye liner91 products
makeup primer85 products
exfoliant/scrub66 products
around-eye cream63 products
hair styling aide61 products
baby wipes59 products
makeup remover56 products
bath oil/salts/soak56 products
hand sanitizer53 products
shaving cream53 products
52 products
hand cream52 products
lip liner51 products
lip balm with SPF51 products
BB cream50 products
antiperspirant/deodorant46 products
anti-aging38 products
body oil37 products
after sun product35 products
CC cream30 products
shaving cream (men's)26 products
beard care25 products
bar soap25 products
bubble bath22 products
lip plumper22 products
sunless tanning21 products
polish remover20 products
toners/astringents20 products
baby lotion19 products
styling gel/lotion19 products
beard oil18 products
hair color and bleaching17 products
diaper cream17 products
body spray15 products
hair spray15 products
baby shampoo14 products
foot moisturizer14 products
baby sunscreen13 products
after shave12 products
fragrance for women11 products
detangler11 products
antiperspirant/deodorant (men's)11 products
other eye makeup9 products
baby soap9 products
nail treatment8 products
nail polish7 products
damaged skin treatment7 products
baby oil6 products
foot cleansing6 products
cuticle treatment5 products
oil controller5 products
toothpaste5 products
eye makeup remover4 products
baby powder4 products
fragrance for men4 products
tanning oil3 products
depilatory3 products
styling mousse/foam3 products
hair relaxer3 products
body powder2 products
muscle/joint soreness2 products
baby bubble bath2 products
glitter2 products
foot odor control1 products
beard cleanser1 products
eyelash glue1 products
skin fading/lightener1 products

Contamination concerns

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Chemical
HYDROQUINONE

Allergies/immunotoxicity

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Concern Reference
Human skin toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments

Cancer

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Concern Reference
tocopheryl acetate enhanced photocarcinogenesis in an animal studyGensler HL, Aickin M, Peng YM, Xu M 1996. Importance of the form of topical vitamin E for prevention of photocarcinogenesis. Nutr Cancer 26(2): 183-91.

Ecotoxicology

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Concern Reference
Suspected to be an environmental toxin and be persistent or bioaccumulative (uncertainty in environmental toxicity or persistence/bioaccumulation)Environment Canada Domestic Substance List
Uncertain environmental toxin and uncertain persistent or bioaccumulativeEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
5742 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • Gensler HL, Aickin M, Peng YM, Xu M 1996. Importance of the form of topical vitamin E for prevention of photocarcinogenesis. Nutr Cancer 26(2): 183-91.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

About this Ingredient's Score Range

  • Products with the EWG VERIFIED mark have met the program’s impurity restrictions based on EWG review of company data.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

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Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer