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TOCOPHERYL ACETATE

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Contamination concerns (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

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lipstick989 products
foundation475 products
concealer306 products
beach & sport sunscreen265 products
moisturizer with SPF231 products
eye shadow206 products
moisturizer197 products
lip gloss193 products
conditioner165 products
facial moisturizer/treatment155 products
bronzer/highlighter155 products
blush142 products
serums & essences138 products
mask119 products
shampoo113 products
body wash/cleanser94 products
brow liner91 products
liquid hand soap70 products
eye liner68 products
facial powder68 products
mascara64 products
lip balm60 products
facial cleanser57 products
around-eye cream53 products
lip balm with SPF48 products
hair treatment/serum48 products
makeup primer47 products
exfoliant/scrub40 products
makeup remover37 products
lip liner37 products
BB cream36 products
body firming lotion34 products
shaving cream31 products
hand cream30 products
anti-aging29 products
CC cream27 products
antiperspirant/deodorant25 products
hand sanitizer23 products
hair styling aide21 products
baby wipes20 products
bath oil/salts/soak16 products
body oil15 products
beard oil13 products
bubble bath13 products
sunless tanning13 products
baby sunscreen12 products
baby lotion12 products
styling gel/lotion12 products
shaving cream (men's)11 products
hair color and bleaching11 products
polish remover11 products
after sun product11 products
bar soap10 products
body spray9 products
other eye makeup9 products
diaper cream9 products
toners/astringents9 products
lip plumper9 products
after shave8 products
baby shampoo8 products
antiperspirant/deodorant (men's)8 products
foot moisturizer8 products
hair spray7 products
baby soap6 products
toothpaste6 products
nail treatment6 products
oil controller5 products
beard care5 products
fragrance for women4 products
damaged skin treatment4 products
detangler4 products
makeup with SPF3 products
baby powder2 products
baby oil2 products
depilatory2 products
cuticle treatment2 products
nail polish2 products
hair relaxer2 products
styling mousse/foam2 products
eye makeup remover1 products
tanning oil1 products
foot cleansing1 products
eyelash glue1 products
muscle/joint soreness1 products
baby bubble bath1 products
glitter1 products
fragrance for men1 products
foot odor control1 products

Contamination concerns

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Chemical
HYDROQUINONE

Allergies/immunotoxicity

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Concern Reference
Human skin toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments

Cancer

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Concern Reference
tocopheryl acetate enhanced photocarcinogenesis in an animal studyGensler HL, Aickin M, Peng YM, Xu M 1996. Importance of the form of topical vitamin E for prevention of photocarcinogenesis. Nutr Cancer 26(2): 183-91.

Ecotoxicology

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Concern Reference
Suspected to be an environmental toxin and be persistent or bioaccumulative (uncertainty in environmental toxicity or persistence/bioaccumulation)Environment Canada Domestic Substance List
Uncertain environmental toxin and uncertain persistent or bioaccumulativeEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
5742 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • Gensler HL, Aickin M, Peng YM, Xu M 1996. Importance of the form of topical vitamin E for prevention of photocarcinogenesis. Nutr Cancer 26(2): 183-91.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

About this Ingredient's Score Range

  • Products with the EWG VERIFIED mark have met the program’s impurity restrictions based on EWG review of company data.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

ABOUT EWG VERIFIED™

Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer