Menu Close Menu

Menu

TOCOPHERYL ACETATE

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Contamination concerns (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

Expand content Collapse content
lipstick1804 products
foundation880 products
concealer610 products
moisturizer484 products
lip gloss466 products
eye shadow378 products
recreational sunscreen368 products
facial moisturizer/treatment367 products
conditioner359 products
daily use with SPF356 products
bronzer/highlighter295 products
blush278 products
shampoo272 products
mask255 products
serums & essences249 products
body wash/cleanser242 products
liquid hand soap202 products
body firming lotion200 products
lip balm197 products
brow liner191 products
facial cleanser178 products
hair treatment/serum172 products
hand sanitizer154 products
mascara143 products
facial powder124 products
exfoliant/scrub119 products
eye liner113 products
makeup primer113 products
hand cream106 products
around-eye cream97 products
hair styling aide93 products
bath oil/salts/soak84 products
shaving cream81 products
makeup remover81 products
CC cream78 products
lip balm with SPF76 products
baby wipes73 products
lip liner70 products
body oil67 products
anti-aging67 products
66 products
antiperspirant/deodorant63 products
BB cream60 products
after sun product49 products
sunless tanning48 products
setting powder/spray48 products
baby sunscreen45 products
bubble bath43 products
bar soap42 products
styling gel/lotion39 products
polish remover38 products
toners/astringents34 products
hair spray31 products
lip plumper31 products
beard care29 products
shaving cream (men's)28 products
nail polish26 products
body spray25 products
foot moisturizer24 products
hair color and bleaching24 products
baby shampoo24 products
beard oil21 products
fragrance for women20 products
antiperspirant/deodorant (men's)18 products
baby lotion18 products
diaper cream18 products
nail treatment17 products
after shave17 products
other eye makeup13 products
tanning oil12 products
baby oil12 products
detangler12 products
foot cleansing12 products
styling mousse/foam11 products
cuticle treatment11 products
baby soap11 products
damaged skin treatment10 products
baby powder9 products
muscle/joint soreness9 products
fragrance for men9 products
glitter8 products
depilatory6 products
eye makeup remover4 products
skin fading/lightener4 products
oil controller4 products
body powder3 products
hair-loss treatment3 products
baby bubble bath3 products
hair relaxer3 products
foot odor control3 products
toothpaste2 products
vapor rubs1 products
beard cleanser1 products
eyelash glue1 products
body art1 products
pore strips1 products

Contamination concerns

Expand content Collapse content
Chemical
HYDROQUINONE

Allergies/immunotoxicity

Expand content Collapse content
Concern Reference
Human skin toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments

Cancer

Expand content Collapse content
Concern Reference
tocopheryl acetate enhanced photocarcinogenesis in an animal studyGensler HL, Aickin M, Peng YM, Xu M 1996. Importance of the form of topical vitamin E for prevention of photocarcinogenesis. Nutr Cancer 26(2): 183-91.

Ecotoxicology

Expand content Collapse content
Concern Reference
Suspected to be an environmental toxin and be persistent or bioaccumulative (uncertainty in environmental toxicity or persistence/bioaccumulation)Environment Canada Domestic Substance List
Uncertain environmental toxin and uncertain persistent or bioaccumulativeEnvironment Canada Domestic Substance List

Data gaps

Expand content Collapse content
Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
5742 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Multiple, additive exposure sources

Expand content Collapse content
Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

Expand content Collapse content
Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

Expand content Collapse content
Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

Expand content Collapse content
Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • Gensler HL, Aickin M, Peng YM, Xu M 1996. Importance of the form of topical vitamin E for prevention of photocarcinogenesis. Nutr Cancer 26(2): 183-91.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

About this Ingredient's Score Range

  • Products with the EWG VERIFIED mark have met the program’s impurity restrictions based on EWG review of company data.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

ABOUT EWG VERIFIED™

Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer