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TOCOPHERYL ACETATE

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Contamination concerns (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

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lipstick935 products
foundation466 products
beach & sport sunscreen343 products
concealer287 products
moisturizer with SPF255 products
eye shadow199 products
moisturizer196 products
lip gloss183 products
facial moisturizer/treatment176 products
conditioner163 products
bronzer/highlighter143 products
blush139 products
serums & essences133 products
mask118 products
shampoo112 products
body wash/cleanser93 products
lip balm91 products
brow liner88 products
facial powder68 products
liquid hand soap68 products
eye liner68 products
mascara61 products
facial cleanser57 products
lip balm with SPF56 products
around-eye cream53 products
body firming lotion52 products
hair treatment/serum44 products
makeup primer41 products
BB cream41 products
exfoliant/scrub40 products
makeup remover35 products
shaving cream30 products
anti-aging29 products
hand cream29 products
CC cream28 products
lip liner25 products
antiperspirant/deodorant24 products
Facial Sun Care24 products
hand sanitizer22 products
makeup with SPF21 products
hair styling aide21 products
baby wipes19 products
baby sunscreen17 products
body oil16 products
bath oil/salts/soak16 products
sunless tanning14 products
beard oil14 products
bubble bath13 products
styling gel/lotion12 products
shaving cream (men's)12 products
baby lotion12 products
after sun product11 products
hair color and bleaching11 products
polish remover11 products
bar soap10 products
diaper cream9 products
toners/astringents9 products
lip plumper9 products
Tanning Sprays9 products
body spray9 products
other eye makeup9 products
antiperspirant/deodorant (men's)8 products
foot moisturizer8 products
after shave8 products
baby shampoo8 products
hair spray7 products
nail treatment6 products
baby soap6 products
toothpaste6 products
oil controller5 products
beard care5 products
tanning oil5 products
fragrance for women4 products
baby oil2 products
detangler2 products
cuticle treatment2 products
nail polish2 products
styling mousse/foam2 products
baby powder2 products
damaged skin treatment2 products
muscle/joint soreness1 products
depilatory1 products
baby bubble bath1 products
hair relaxer1 products
fragrance for men1 products
foot odor control1 products
Oils & Serums1 products
Under Eye Concealers1 products
eye makeup remover1 products
foot cleansing1 products
eyelash glue1 products

Contamination concerns

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Chemical
HYDROQUINONE

Allergies/immunotoxicity

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Concern Reference
Human skin toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments

Cancer

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Concern Reference
tocopheryl acetate enhanced photocarcinogenesis in an animal studyGensler HL, Aickin M, Peng YM, Xu M 1996. Importance of the form of topical vitamin E for prevention of photocarcinogenesis. Nutr Cancer 26(2): 183-91.

Ecotoxicology

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Concern Reference
Suspected to be an environmental toxin and be persistent or bioaccumulative (uncertainty in environmental toxicity or persistence/bioaccumulation)Environment Canada Domestic Substance List
Uncertain environmental toxin and uncertain persistent or bioaccumulativeEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
5742 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • Gensler HL, Aickin M, Peng YM, Xu M 1996. Importance of the form of topical vitamin E for prevention of photocarcinogenesis. Nutr Cancer 26(2): 183-91.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

About this Ingredient's Score Range

  • Products with the EWG VERIFIED mark have met the program’s impurity restrictions based on EWG review of company data.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

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Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer